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相关论文: Cell Tracking via Proposal Generation and Selectio…

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Tracking living cells in video sequence is difficult, because of cell morphology and high similarities between cells. Tracking-by-detection methods are widely used in multi-cell tracking. We perform multi-cell tracking based on the cell…

计算机视觉与模式识别 · 计算机科学 2019-06-27 Zibin Zhou , Fei Wang , Wenjuan Xi , Huaying Chen , Peng Gao , Chengkang He

Cell tracking remains a pivotal yet challenging task in biomedical research. The full potential of deep learning for this purpose is often untapped due to the limited availability of comprehensive and varied training data sets. In this…

计算机视觉与模式识别 · 计算机科学 2024-04-30 Moritz Sturm , Lorenzo Cerrone , Fred A. Hamprecht

An automatic approach to counting any kind of cells could alleviate work of the experts and boost the research in fields such as regenerative medicine. In this paper, a method for microscopy cell counting using multiple frames (hence…

计算机视觉与模式识别 · 计算机科学 2018-02-01 Alexander Gomez Villa , Augusto Salazar , Igor Stefanini

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Sota Kato , Kazuhiro Hotta

Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

计算机视觉与模式识别 · 计算机科学 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

定量方法 · 定量生物学 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

图像与视频处理 · 电气工程与系统科学 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

We present a method for microtubule tracking in electron microscopy volumes. Our method first identifies a sparse set of voxels that likely belong to microtubules. Similar to prior work, we then enumerate potential edges between these…

计算机视觉与模式识别 · 计算机科学 2020-09-18 Nils Eckstein , Julia Buhmann , Matthew Cook , Jan Funke

Cell counting in microscopy images is vital in medicine and biology but extremely tedious and time-consuming to perform manually. While automated methods have advanced in recent years, state-of-the-art approaches tend to increasingly…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

The nematode Caenorhabditis elegans (C. elegans) is used as a model organism to better understand developmental biology and neurobiology. C. elegans features an invariant cell lineage, which has been catalogued and observed using…

计算机视觉与模式识别 · 计算机科学 2022-08-03 Andrew Lauziere , Ryan Christensen , Hari Shroff

A human watching a video of closely-packed cells can generally identify every individual cell, regardless of density and noise, but most currently-available cell-tracking software cannot. This is because the human brain automatically builds…

细胞行为 · 定量生物学 2017-09-27 Huy Pham , Emile Ramez Shehada , Shawna Stahlheber , Wayne B. Hayes

Determining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative…

定量方法 · 定量生物学 2024-03-05 Baiyang Dai , Jiamin Yang , Hari Shroff , Patrick La Riviere

Cell shape analysis is important in biomedical research. Deep learning methods may perform to segment individual cells if they use sufficient training data that the boundary of each cell is annotated. However, it is very time-consuming for…

图像与视频处理 · 电气工程与系统科学 2020-02-26 Kazuya Nishimura , Dai Fei Elmer Ker , Ryoma Bise

Particle tracking is a powerful biophysical tool that requires conversion of large video files into position time series, i.e. traces of the species of interest for data analysis. Current tracking methods, based on a limited set of input…

定量方法 · 定量生物学 2018-10-09 Jay M. Newby , Alison M. Schaefer , Phoebe T. Lee , M. Gregory Forest , Samuel K. Lai

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

定量方法 · 定量生物学 2022-10-05 André O. Françani

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

计算机视觉与模式识别 · 计算机科学 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

Signaling pathways are responsible for the regulation of cell processes, such as monitoring the external environment, transmitting information across membranes, and making cell fate decisions. Given the increasing amount of biological data…

分子网络 · 定量生物学 2020-04-07 Daniel Inostroza , Cecilia Hernández , Diego Seco , Gonzalo Navarro , Alvaro Olivera-Nappa

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

基因组学 · 定量生物学 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains unclear what current representation learning methods actually…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Ivan Svatko , Maxime Sanchez , Ihab Bendidi , Gilles Cottrell , Auguste Genovesio

High-throughput screening techniques, such as microscopy imaging of cellular responses to genetic and chemical perturbations, play a crucial role in drug discovery and biomedical research. However, robust perturbation screening for…

计算机视觉与模式识别 · 计算机科学 2025-07-16 Jiayuan Chen , Thai-Hoang Pham , Yuanlong Wang , Ping Zhang