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Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

Many complex systems - be they financial, natural, or social - are composed of units - such as stocks, neurons, or agents - whose joint activity can be represented as a multivariate time series. An issue of both practical and theoretical…

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

机器学习 · 统计学 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

计算机视觉与模式识别 · 计算机科学 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Due to their parsimony, separable covariance models have been popular in modeling matrix-variate data. However, the inference from such a model may be misleading if the population covariance matrix $\Sigma$ is actually non-separable,…

统计理论 · 数学 2026-05-05 Bongjung Sung , Peter D. Hoff

This paper considers joint analysis of multiple functionally related structures in classification tasks. In particular, our method developed is driven by how functionally correlated brain structures vary together between autism and control…

机器学习 · 统计学 2021-09-08 Zhiyuan Liu , Jörn Schulz , Mohsen Taheri , Martin Styner , James Damon , Stephen Pizer , J. S. Marron

The entrainment between weakly-coupled nonlinear oscillators, as well as between complex signals such as those representing physiological activity, is frequently assessed in terms of whether a stable relationship is detectable between the…

神经元与认知 · 定量生物学 2019-02-27 Ludovico Minati , Natsue Yoshimura , Mattia Frasca , Stanislaw Drozdz , Yasuharu Koike

Many modern datasets, from areas such as neuroimaging and geostatistics, come in the form of a random sample of tensor-valued data which can be understood as noisy observations of a smooth multidimensional random function. Most of the…

统计方法学 · 统计学 2023-09-18 William Consagra , Arun Venkataraman , Xing Qiu

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

统计方法学 · 统计学 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Functional magnetic resonance imaging (fMRI) is now a well-established technique for studying the brain. However, in many situations, such as when data are acquired in a resting state, it is difficult to know whether the data are truly…

应用统计 · 统计学 2013-01-15 John A. D. Aston , Claudia Kirch

An important problem in neuroscience is to understand how brains extract relevant signals from mixtures of unknown sources, i.e., perform blind source separation. To model how the brain performs this task, we seek a biologically plausible…

信号处理 · 电气工程与系统科学 2022-03-08 David Lipshutz , Cengiz Pehlevan , Dmitri B. Chklovskii

Classification is a core topic in functional data analysis. A large number of functional classifiers have been proposed in the literature, most of which are based on functional principal component analysis or functional regression. In…

统计方法学 · 统计学 2025-10-14 Ruoxu Tan , Yiming Zang

Functional differentiation in the brain emerges as distinct regions specialize and is key to understanding brain function as a complex system. Previous research has modeled this process using artificial neural networks with specific…

神经元与认知 · 定量生物学 2025-11-17 Yuki Tomoda , Ichiro Tsuda , Yutaka Yamaguti

We present a method for detection of weak continuous signals from sources in binary systems via the incoherent combination of many "short" coherently-analyzed segments. The main focus of the work is on the construction of a metric on the…

广义相对论与量子宇宙学 · 物理学 2015-05-30 Chris Messenger

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

定量方法 · 定量生物学 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

For nonparametric inference about a function, multiscale testing procedures resolve the need for bandwidth selection and achieve asymptotically optimal detection performance against a broad range of alternatives. However, critical values…

统计理论 · 数学 2025-06-06 Johann Köhne , Fabian Mies

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

神经元与认知 · 定量生物学 2017-04-03 Jiancheng Zhuang

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

统计计算 · 统计学 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

统计理论 · 数学 2008-08-08 Chunming Zhang , Tao Yu