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The Zika virus is the primary suspect in the large increase in microcephaly cases in 2015-6 in Brazil, however its role is unconfirmed despite individual cases of viral infections found in neural tissue. Here we consider the alternative…

定量方法 · 定量生物学 2016-04-14 Dan Evans , Fred Nijhout , Raphael Parens , Alfredo J. Morales , Yaneer Bar-Yam

The Zika virus, known for its potential to induce neurological conditions such as microcephaly when transmitted vertically from infected mothers to infants, has sparked widespread concerns globally. Motivated by this, we propose an optimal…

最优化与控制 · 数学 2024-11-12 Dilara Yapışkan , Cristiana J. Silva , Delfim F. M. Torres

We propose a new mathematical model for the spread of Zika virus. Special attention is paid to the transmission of microcephaly. Numerical simulations show the accuracy of the model with respect to the Zika outbreak occurred in Brazil.

种群与进化 · 定量生物学 2018-11-30 Faical Ndairou , Ivan Area , Juan J. Nieto , Cristiana J. Silva , Delfim F. M. Torres

As per the records of theWorld Health Organization, the first formally reported incidence of Zika virus occurred in Brazil in May 2015. The disease then rapidly spread to other countries in Americas and East Asia, affecting more than…

种群与进化 · 定量生物学 2020-09-29 Marwah Soliman , Vyacheslav Lyubchich , Yulia R. Gel

Although Zika virus (ZIKV) seems to be prominently neurotropic, there are some reports of involvement of other organs, particularly the heart. Of special concern are those children exposed prenatally to ZIKV and born with no microcephaly or…

定量方法 · 定量生物学 2021-05-17 Christophe L. Herry , Helena M. F. Soares , Lavinia Schuler-Faccini , Martin G. Frasch

Zika virus (ZIKV), a disease spread primarily through the Aedes aegypti mosquito, was identified in Brazil in 2015 and was declared a global health emergency by the World Health Organization (WHO). Epidemiologists often use common…

种群与进化 · 定量生物学 2017-01-27 Derek Lo , Briton Park

Background: The choice of efficient antipsychotic therapy for schizophrenia relies on a time-consuming trial-and-error approach, whereas the social and economic burdens of the disease call for faster alternatives. Material \& methods: In a…

Introduction: Zika epidemic in America was declared a public health emergency of international concern after the rapid spread in the region. Stratification of the potential transmission of the disease is needed to address the efforts…

Infant mortality, by which we understand the postnatal stage during which mortality is declining, is a manifestation and embodiment of congenital abnormalities. Severe defects will translate into death occurring shortly after birth whereas…

In November 2015, El Salvador reported their first case of Zika virus (Zv) leading to an explosive outbreak that in just two months had over 6000 suspected cases. Many communities along with national agencies initiated the process to…

种群与进化 · 定量生物学 2016-03-18 Victor Moreno , Baltazar Espinoza , Derdei Bichara , Susan A. Holechek , Carlos Castillo-Chavez

This paper presents a mathematical model to investigate co-infection with HIV/AIDS and zika virus (ZIKV) in Colombia and Brazil, where the first cases were reported in 2015-2016. The model considers the sexual transmission dynamics of both…

种群与进化 · 定量生物学 2024-04-17 Jhoana P. Romero-Leiton , Idriss Sekkak , Julien Arino , Bouchra Nasri

Vector-transmitted diseases such as dengue fever and chikungunya have been spreading rapidly in many parts of the world. The Zika virus has been known since 1947 and invaded South America in 2013. It can be transmitted not only by…

种群与进化 · 定量生物学 2016-08-23 Fred Brauer , Carlos Castillo-Chavez , Anuj Mubayi , Sherry Towers

The Human Genome Project (HGP) provides researchers with the data of nearly all human genes and the challenge to use this information for elucidating the etiology of common disorders. A secondary Darwinian method was applied to HGP and…

无序系统与神经网络 · 物理学 2015-03-26 Hans W. M. Moises

The entropic brain hypothesis holds that the key facts concerning psychedelics are partially explained in terms of increased entropy of the brain's functional connectivity. Ayahuasca is a psychedelic beverage of Amazonian indigenous origin…

神经元与认知 · 定量生物学 2017-08-10 A. Viol , Fernanda Palhano-Fontes , Heloisa Onias , Draulio B. de Araujo , G. M. Viswanathan

The ongoing Zika virus (ZIKV) epidemic poses a major global public health emergency. It is known that ZIKV is spread by \textit{Aedes} mosquitoes, recent studies show that ZIKV can also be transmitted via sexual contact and cases of…

种群与进化 · 定量生物学 2016-07-08 Daozhou Gao , Yijun Lou , Daihai He , Travis C. Porco , Yang Kuang , Gerardo Chowell , Shigui Ruan

The study of brain networks, including derived from functional neuroimaging data, attracts broad interest and represents a rapidly growing interdisciplinary field. Comparing networks of healthy volunteers with those of patients can…

神经元与认知 · 定量生物学 2018-06-05 Emma K. Towlson , Petra E. Vértes , Ulrich Müller , Sebastian E. Ahnert

Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such…

There has been a large number of reported cases of the occurrence of Zika in different countries in 2016 and it is necessary to develop an early warning system to initiate preventive campaigns against the disease. A potential early warning…

种群与进化 · 定量生物学 2016-07-12 Raul Isea

Local climate conditions play a major role in the development of the mosquito population responsible for transmitting Dengue Fever. Since the {\em Aedes Aegypti} mosquito is also a primary vector for the recent Zika and Chikungunya…

定量方法 · 定量生物学 2017-01-03 Lucas Stolerman , Pedro Maia , J. Nathan Kutz

Reducing antibiotic usage in livestock animals has become an urgent issue worldwide to prevent antimicrobial resistance. Here, abuse of chlortetracycline (CTC), a versatile antibacterial agent, on the performance, blood components, fecal…

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