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Proteins are large and complex molecular machines. In order to perform their function, most of them need energy, e.g. either in the form of a photon, like in the case of the visual pigment rhodopsin, or through the breaking of a chemical…

生物大分子 · 定量生物学 2009-11-13 Francesco Piazza , Yves-Henri Sanejouand

The energy dissipated by a living organism is commonly identified with heat generation. However, as cells exchange metabolites with their environment they also dissipate energy in the form of chemical entropy. How dissipation is distributed…

其他定量生物学 · 定量生物学 2025-10-09 Tommaso Cossetto , Jonathan Rodenfels , Pablo Sartori

ATP-hydrolysis is the basic energy source of many physiological processes, but there is a lack of knowledge regarding its biological role other than energy transfer and thermogenesis. Not all the energy released by ATP-hydrolysis could be…

生物大分子 · 定量生物学 2013-04-30 Xin Liu

In this study, the additional heat capacity which appear during the water dissociation of the proteins that are one of the soft materials, have been considered by the statistical mechanical methods. For this purpose, taking the electric…

统计力学 · 物理学 2007-05-23 G. Oylumluoglu , F. Buyukkilic , D. Demirhan

The energy transition is also about switching to electricity-based technologies such as heat pumps and electric mobility. They avoid heat as an intermediate step and are therefore much more efficient. This can significantly reduce the…

科普物理 · 物理学 2025-06-17 Axel Kleidon , Harald Lesch

Fueled by the hydrolysis of ATP, the motor protein kinesin literally walks on two legs along the biopolymer microtubule. The number of accidental backsteps that kinesin takes appears to be much larger than what one would expect given the…

亚细胞过程 · 定量生物学 2009-11-13 M. Bier , F. J. Cao

The theory describing action of medicines explored in this paper is based on assumption that vital activity of the cell may be described in terms of the model of two states: resting state and excitation. According to available physiological…

生物物理 · 物理学 2012-08-21 V. V. Matveev , D. V. Prokhorenko

During contraction the energy of muscle tissue increases due to energy from the hydrolysis of ATP. This energy is distributed across the tissue as strain-energy potentials in the contractile elements, strain-energy potential from the 3D…

生物物理 · 物理学 2021-01-13 J. M. Wakeling , S. A. Ross , D. S. Ryan , B. Bolsterlee , R. Konno , S. Domínguez , N. Nigam

Recent studies reported that adenosine triphosphate (ATP) could inhibit as well as enhance the phase separation in prion-like proteins. The molecular mechanism underlying such a puzzling phenomenon remains elusive. Here, taking the fused in…

软凝聚态物质 · 物理学 2022-09-22 Chun-Lai Ren , Yue Shan , Pengfei Zhang , Hong-Ming Ding , Yu-qiang Ma

An imbalance between energy intake and energy expenditure will lead to a change in body weight (mass) and body composition (fat and lean masses). A quantitative understanding of the processes involved, which currently remains lacking, will…

组织与器官 · 定量生物学 2015-05-13 Carson C. Chow , Kevin D. Hall

Integrated global food system analysis is hampered by the fragmentation of data among food types, processes, and scales. Studies also often neglect the connection to human metabolism -- the ultimate driver of food demand. Here we use a…

物理与社会 · 物理学 2025-08-05 Maxwell Kaye , Graham K. MacDonald , Eric Galbraith

Mitochondria are critical organelles in eukaryotes that produce the energy currency ATP. In nerve axons, mitochondria are known to align at almost regular intervals to maintain a constant ATP concentration, but little is known about the…

生物物理 · 物理学 2023-05-10 Masashi K. Kajita , Yoshiyuki Konishi , Tetsuhiro S. Hatakeyama

In living cells, oscillation of the concentration of cytosolic Ca2+ is an important and pervasive signal for the intercellular and intracellular information conduction. To generate the oscillation, the hydrolysis of ATP is always needed.…

细胞行为 · 定量生物学 2018-11-27 Yingda Ge , Congjian Ni , Yunsheng Sun , Fangting Li

Adenosine 5'-triphosphate (ATP) is the nearly ubiquitous "energy currency" of living organisms, and thus is a crucial participant in the majority of enzymatic reactions. The standard models in enzyme kinetics generally ignore the temporal…

分子网络 · 定量生物学 2014-06-10 Jasmine Nirody , Padmini Rangamani

Life is an exergonic chemical reaction. Many individual reactions in metabolism entail slightly endergonic steps that are coupled to free energy release, typically as ATP hydrolysis, in order to go forward. ATP is almost always supplied by…

生物物理 · 物理学 2025-10-10 Natalia Mrnjavac , William F. Martin

The utilization of glycolysis in aerobic conditions have been a subject of debate for more than a century. A hypothesis supported by previous data is that glycolysis has a higher rate of ATP production per protein mass and per occupied…

生物大分子 · 定量生物学 2024-03-25 Alexei Vazquez

Heat dissipation is ubiquitous in living systems, which constantly convert distinct forms of energy into each other. The transport of thermal energy in liquids and even within proteins is well understood but kinetic energy transfer across a…

软凝聚态物质 · 物理学 2026-01-07 Brandon Neff , Matthias Heyden

Kinesin and related motor proteins utilize ATP fuel to propel themselves along the external surface of microtubules in a processive and directional fashion. We show that the observed step-like motion is possible through time varying charge…

生物大分子 · 定量生物学 2007-05-23 A. Ciudad , J. M. Sancho , G. P. Tsironis

The energetics of the stochastic process has shown the balance of energy on the mesoscopic level. The heat and the energy defined there are, however, generally different from their macroscopic counterpart. We show that this discrepancy can…

统计力学 · 物理学 2009-11-13 Ken Sekimoto

The chemical composition of the earths atmosphere far from equilibrium is unique in the solar system and has been attributed to the presence of widespread life. Here I show that this perspective can be quantified using non-equilibrium…

适应与自组织系统 · 物理学 2015-05-27 Axel Kleidon
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