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We present a fast, high-throughput method for characterizing the motility of microorganisms in 3D based on standard imaging microscopy. Instead of tracking individual cells, we analyse the spatio-temporal fluctuations of the intensity in…

We present a highly efficient workflow for designing semiconductor structures with specific physical properties, which can be utilized for a range of applications, including photocatalytic water splitting. Our algorithm generates candidate…

Amphiphilic molecules spontaneously form self-assembled structures of various shapes depending on their molecular structures, the temperature, and other physical conditions. The functionalities of these structures are dictated by their…

软凝聚态物质 · 物理学 2024-04-18 Takeo Sudo , Satoki Ishiai , Yuuki Ishiwatari , Takahiro Yokoyama , Kenji Yasuoka , Noriyoshi Arai

Plant phenotyping, that is, the quantitative assessment of plant traits including growth, morphology, physiology, and yield, is a critical aspect towards efficient and effective crop management. Currently, plant phenotyping is a manually…

计算机视觉与模式识别 · 计算机科学 2021-04-15 Annalisa Milella , Roberto Marani , Antonio Petitti , Giulio Reina

Motile microorganisms, like bacteria and algae, unify abilities like self-propulsion, autonomous navigation, and decision-making on the micron scale. While recent breakthroughs have led to the creation of synthetic microswimmers and…

软凝聚态物质 · 物理学 2026-02-06 Aritra K. Mukhopadhyay , Ran Niu , Linhui Fu , Kai Feng , Christopher Fujta , Qiang Zhao , Jinping Qu , Benno Liebchen

Understanding the dependence and interplay between architecture and function in biological networks has great relevance to disease progression, biological fabrication and biological systems in general. We propose methods to assess the…

定量方法 · 定量生物学 2009-10-17 Soumen Roy , Vladimir Filkov

Supernova cosmology without spectroscopic confirmation is an exciting new frontier which we address here with the Bayesian Estimation Applied to Multiple Species (BEAMS) algorithm and the full three years of data from the Sloan Digital Sky…

Genome-scale stoichiometric modeling of metabolism has become a standard systems biology tool for modeling cellular physiology and growth. Extensions of this approach are also emerging as a valuable avenue for predicting, understanding and…

Crohn's disease (CD) is associated with an ecological imbalance of the intestinal microbiota, consisting of hundreds of species. The underlying complexity as well as individual differences between patients contributes to the difficulty to…

分子网络 · 定量生物学 2017-09-19 Eugen Bauer , Ines Thiele

Counting microbial colonies is a fundamental task in microbiology and has many applications in numerous industry branches. Despite this, current studies towards automatic microbial counting using artificial intelligence are hardly…

计算机视觉与模式识别 · 计算机科学 2022-09-07 Sylwia Majchrowska , Jarosław Pawłowski , Natalia Czerep , Aleksander Górecki , Jakub Kuciński , Tomasz Golan

This paper discusses an optimization method called Modified Bee Colony algorithm (MBC) based on a particular intelligent behavior of honeybee swarms. The algorithm was checked in a few benchmarks like Shekel, Rozenbroke, Himmelblau and…

计算工程、金融与科学 · 计算机科学 2020-03-06 Vasiliy V. Grigoriev , Oleg Iliev , Petr N. Vabishchevich

In this paper we consider a statistical estimation problem known as atomic deconvolution. Introduced in reliability, this model has a direct application when considering biological data produced by flow cytometers. In these experiments,…

统计理论 · 数学 2017-10-12 Manon Costa , Sébastien Gadat , Pauline Gonnord , Laurent Risser

Underwater surveys conducted using divers or robots equipped with customized camera payloads can generate a large number of images. Manual review of these images to extract ecological data is prohibitive in terms of time and cost, thus…

计算机视觉与模式识别 · 计算机科学 2020-09-22 Scarlett Raine , Ross Marchant , Peyman Moghadam , Frederic Maire , Brett Kettle , Brano Kusy

Multicellular systems play a key role in bioprocess and biomedical engineering. Cell ensembles encountered in these setups show phenotypic variability like size and biochemical composition. As this variability may result in undesired…

系统与控制 · 计算机科学 2018-07-16 Armin Küper , Robert Dürr , Steffen Waldherr

Automated stomata detection and measuring are vital for understanding plant physiological performance and ecological functioning in global water and carbon cycles. Current methods are laborious, time-consuming, prone to bias, and limited in…

组织与器官 · 定量生物学 2024-04-04 Jiaxin Wang , Heidi J. Renninger , Qin Ma , Shichao Jin

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

定量方法 · 定量生物学 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional methods of characterization. Environmental shotgun sequencing…

基因组学 · 定量生物学 2007-08-24 Sourav Chatterji , Ichitaro Yamazaki , Zhaojun Bai , Jonathan Eisen

Super-resolution imaging techniques have largely improved our capabilities to visualize nanometric structures in biological systems. Their application further enables one to potentially quantitate relevant parameters to determine the…

生物物理 · 物理学 2019-12-18 Tina Kosǔta , Marta Cullell-Dalmau , Francesca Cella Zanacchi , Carlo Manzo

Automated segmentation of individual leaves of a plant in an image is a prerequisite to measure more complex phenotypic traits in high-throughput phenotyping. Applying state-of-the-art machine learning approaches to tackle leaf instance…

计算机视觉与模式识别 · 计算机科学 2019-03-25 Daniel Ward , Peyman Moghadam , Nicolas Hudson

The spread of microbial infections is governed by the self-organization of bacteria on surfaces. Limitations of live imaging techniques make collective behaviors in clinically relevant systems challenging to quantify. Here, novel…

生物物理 · 物理学 2024-07-19 Vincent Hickl , Abid Khan , René M. Rossi , Bruno F. B. Silva , Katharina Maniura-Weber