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Overweight and obesity remain a major global public health concern and identifying the individualized patterns that increase the risk of future weight gains has a crucial role in preventing obesity and numerous sub-sequent diseases…

机器学习 · 计算机科学 2021-11-09 Mina Samizadeh , Jessica C Jones-Smith , Bethany Sheridan , Rahmatollah Beheshti

Obesity is associated with higher fatality risk and altered distribution of occupant injuries in motor vehicle crashes partially because of the increased depth of abdominal soft tissue, which results in limited and delayed engagement of the…

The twin paradox of the special theory of relativity has given rise to a large body of literature discussing its implications. In its standard form, the traveler changes velocity only at the destination of the trip, so that he appears to…

综合物理 · 物理学 2016-10-12 David A. de Wolf

Background: Diabetes is associated with obesity, poor glucose control and sleep dysfunction which impair cognitive and psychomotor functions, and, in turn, increase driver risk. How this risk plays out in the real-world driving settings is…

A prominent threat to causal inference about peer effects over social networks is the presence of homophily bias, that is, social influence between friends and families is entangled with common characteristics or underlying similarities…

统计方法学 · 统计学 2020-02-18 Lan Liu , Eric Tchetgen Tchetgen

Recently, we have shown that the age-specific prevalence of a disease can be related to the transition rates in the illness-death model via a partial differential equation (PDE). In case of a chronic disease, we show that the PDE can be…

种群与进化 · 定量生物学 2017-12-29 Ralph Brinks

Obesity is a global health concern associated with high morbidity and mortality. Therapeutic strategies include synthetic drugs and surgery, which may entail high costs and serious complications. Plant-based medicinal agents offer an…

其他定量生物学 · 定量生物学 2012-08-10 Mahnaz Kazemipoor , Che Wan Jasimah Wan Mohamed Radzi , Geoffrey A. Cordell , Iman Yaze

Significant overweight represents a major health problem in industrialized countries. Besides its known metabolic origins, this condition may also have an infectious cause, as recently postulated. Here, it is surmised that the potentially…

生物大分子 · 定量生物学 2008-09-16 Razvan Tudor Radulescu

We present a new experiment demonstrating destructive interference in customers' estimates of conditional probabilities of product failure. We take the perspective of a manufacturer of consumer products, and consider two situations of cause…

人工智能 · 计算机科学 2022-06-01 Irina Basieva , Vijitashwa Pandey , Polina Khrennikova

Overweight and obesity in adults are known to be associated with risks of metabolic and cardiovascular diseases. Because obesity is an epidemic, increasingly affecting children, it is important to understand if this condition persists from…

Several approaches to causal inference from observational studies have been proposed. Since the proposal of Rubin (1974) many works have developed a counterfactual approach to causality, statistically formalized by potential outcomes. Pearl…

统计方法学 · 统计学 2019-05-06 Daniel Commenges

In making models for biological systems one expects to grasp the biology and be able to use ones intuition to predict the outcome. This paper is about the discrepancy between what is expected and what is the outcome of the analysis of the…

种群与进化 · 定量生物学 2024-04-05 Joost H. J. van Opheusden , Lia Hemerik

Obesity is a major health problem, increasing the risk of various major chronic diseases, such as diabetes, cancer, and stroke. While the role of obesity identified by cross-sectional BMI recordings has been heavily studied, the role of BMI…

机器学习 · 计算机科学 2024-12-03 Md Mozaharul Mottalib , Jessica C Jones-Smith , Bethany Sheridan , Rahmatollah Beheshti

Deep sequence models for blood glucose forecasting consistently fail to leverage clinically informative drivers--insulin, meals, and activity--despite well-understood physiological mechanisms. We term this Driver-Blindness and formalize it…

机器学习 · 计算机科学 2025-11-26 Heman Shakeri

Causal effects are commonly defined as comparisons of the potential outcomes under treatment and control, but this definition is threatened by the possibility that the treatment or control condition is not well-defined, existing instead in…

统计方法学 · 统计学 2019-04-26 Raiden B. Hasegawa , Sameer K. Deshpande , Dylan S. Small , Paul R. Rosenbaum

OBJECTIVES: Changes in the way dietary fat is metabolized can be considered causative in obesity. The role of sedentary behavior in this defect has not been determined. We hypothesized that physical inactivity partitions dietary fats toward…

In the context of the global obesity epidemic, it is important to know who becomes obese and why. However, the processes that determine the changing shape of Body Mass Index (BMI) distributions in high-income societies are not…

物理与社会 · 物理学 2018-02-07 John C. Lang , Hans De Sterck , Daniel M. Abrams

Well known Simpson's paradox is puzzling and surprising for many, especially for the empirical researchers and users of statistics. However there is no surprise as far as mathematical details are concerned. A lot more is written about the…

其他统计学 · 统计学 2018-04-24 Priyantha Wijayatunga

Diabetes is an epidemic disease of the 21st century and is growing globally. Although, final diabetes treatments and cure are still on research phase, related complications of diabetes endanger life of diabetic patients. Diabetic coma which…

人机交互 · 计算机科学 2016-08-15 Vahid Hosseini

Diabetes mellitus is a disease which is currently a huge health hazard globally. The cases of diabetes had increased by a significant amount in past decades. Also it has been predicted that it will further increase in future. Diabetes…

生物物理 · 物理学 2023-08-01 Sourav Chowdhury , Suparna Roychowdhury , Indranath Chaudhuri