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相关论文: Multiple Signal Classification Algorithm for super…

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Multiple signal classification algorithm (MUSICAL) provides a super-resolution microscopy method. In the previous research, MUSICAL has enabled data-parallelism well on a desktop computer or a Linux-based server. However, the running time…

分布式、并行与集群计算 · 计算机科学 2022-06-14 Quan Do , Jon Ivar Kristiansen , Krishna Agarwal , Phuong Hoai Ha

Multiple signal classification algorithm (MUSICAL) exploits temporal fluctuations in fluorescence intensity to perform super-resolution microscopy by computing the value of a super-resolving indicator function across a fine sample grid. A…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Sebastian Acuña , Ida S. Opstad , Fred Godtliebsen , Balpreet Singh Ahluwalia , Krishna Agarwal

The diffraction of light imposes a fundamental limit on the resolution of light microscopes. This limit can be circumvented by creating and exploiting independent behaviors of the sample at length scales below the diffraction limit. In…

生物物理 · 物理学 2024-06-19 Mohamadreza Fazel , Michael J. Wester

In this paper, we study the MUltiple SIgnal Classification (MUSIC) algorithm often used to image small targets when multiple measurement vectors are available. We show that this algorithm may be used when the imaging problem can be cast as…

数值分析 · 数学 2019-01-23 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique in biomedical research that uses the fluorophore decay rate to provide additional contrast in fluorescence microscopy. However, at present, the calculation, analysis,…

图像与视频处理 · 电气工程与系统科学 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Cara Ravasio , Scott S. Howard

Super-resolution Structured Illumination Microscopy (SR-SIM) enables fluorescence microscopy beyond the diffraction limit at high frame rates. Compared to other super-resolution microscopy techniques, the low photon fluence used in SR-SIM…

Fluorescence fluctuations-based super-resolution microscopy (FF-SRM) is an emerging field promising low-cost and live-cell compatible imaging beyond the resolution of conventional optical microscopy. A comprehensive overview on how the…

In fluorescence microscopy, Single Molecule Localization Microscopy (SMLM) techniques aim at localizing with high precision high density fluorescent molecules by stochastically activating and imaging small subsets of blinking emitters.…

Confocal microscopy has long been a cornerstone technique for visualizing complex interactions and processes within cellular structures. However, achieving super-resolution imaging of multiple organelles and their interactions…

光学 · 物理学 2025-08-19 Qinglin Chen , Luwei Wang , Jia Li , Dan Shao , Xiaoyu Weng , Liwei Liu , Dayong Jin , Junle Qu

Molecular fluorescence microscopy is a leading approach to super-resolution and nanoscale imaging in life and material sciences. However, super-resolution fluorescence microscopy is often bottlenecked by system-specific calibrations and…

Single molecule localization microscopy (SMLM) techniques enable imaging biological samples well beyond the diffraction limit of light, but they vary significantly in their spatial and temporal resolutions. High-order statistical analysis…

生物物理 · 物理学 2016-03-15 Shachar Schidorsky , Xiyu Yi , Yair Razvag , Yonatan Golan , Shimon Weiss , Eilon Sherman

This paper presents a performance analysis of the MUltiple SIgnal Classification (MUSIC) algorithm applied on $D$ dimensional single-snapshot spectral estimation while $s$ true frequencies are located on the continuum of a bounded domain.…

信息论 · 计算机科学 2016-11-17 Wenjing Liao

Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…

In this contribution, we consider MUltiple SIgnal Classification (MUSIC)-type algorithm for a non-iterative microwave imaging of small and arbitrary shaped extended anomalies located in a homogeneous media from scattering matrix whose…

数值分析 · 数学 2024-11-13 Won-Kwang Park

We propose an efficient algorithm for reconstructing one-dimensional wide-band line spectra from their Fourier data in a bounded interval $[-\Omega,\Omega]$. While traditional subspace methods such as MUSIC achieve super-resolution for…

信号处理 · 电气工程与系统科学 2023-10-30 Zetao Fei , Hai Zhang

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

生物大分子 · 定量生物学 2015-04-15 Mark Leake

Fast 3D super-resolution imaging is essential for decoding rapidly occurring biological processes. Encoding single molecules to their respective planes enable simultaneous multi-plane super-resolution volume imaging. This saves the…

生物物理 · 物理学 2016-08-04 Partha Pratim Mondal

In fluorescence microscopy, spectral unmixing aims to recover individual fluorophore concentrations from spectral images that capture mixed fluorophore emissions. Since classical methods operate pixel-wise and rely on least-squares fitting,…

计算机视觉与模式识别 · 计算机科学 2026-03-26 Federico Carrara , Talley Lambert , Mehdi Seifi , Florian Jug

Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

计算机视觉与模式识别 · 计算机科学 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Fluorescence microscopy is a critical tool across various disciplines, from materials science to biomedical research, yet it is limited by the diffraction limit of resolution. Advanced super-resolution techniques such as localization…

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