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Conducting valid statistical analyses is challenging in the presence of missing-not-at-random (MNAR) data, where the missingness mechanism is dependent on the missing values themselves even conditioned on the observed data. Here, we…

统计方法学 · 统计学 2023-06-13 Anna Guo , Jiwei Zhao , Razieh Nabi

During the past few decades, missing-data problems have been studied extensively, with a focus on the ignorable missing case, where the missing probability depends only on observable quantities. By contrast, research into non-ignorable…

统计方法学 · 统计学 2019-08-06 Yukun Liu , Pengfei Li , Jing Qin

Methods are lacking to handle the problem of survival analysis in the presence of an interval-censored covariate, specifically the case in which the conditional hazard of the primary event of interest depends on the occurrence of a…

Cross-sectional HIV incidence estimation leverages recency test results to determine the HIV incidence of a population of interest, where recency test uses biomarker profiles to infer whether an HIV-positive individual was "recently"…

统计方法学 · 统计学 2023-11-21 Qi Wang , Ann Duerr , Fei Gao

The minimum description length (MDL) principle states that the best model to account for some data minimizes the sum of the lengths, in bits, of the descriptions of the model and the residual error. The description length is thus a…

The probability-scale residual (PSR) is well defined across a wide variety of variable types and models, making it useful for studies of HIV/AIDS. In this manuscript, we highlight some of the properties of the PSR and illustrate its…

应用统计 · 统计学 2018-03-02 Bryan E. Shepherd , Qi Liu , Valentine Wanga , Chun Li

Missing outcome data is one of the principal threats to the validity of treatment effect estimates from randomized trials. The outcome distributions of participants with missing and observed data are often different, which increases the…

统计方法学 · 统计学 2017-04-06 Iván Díaz , Mark J. van der Laan

Government statistical agencies often apply statistical disclosure limitation techniques to survey microdata to protect the confidentiality of respondents. There is a need for valid and practical ways to assess the protection provided. This…

应用统计 · 统计学 2010-11-15 Natalie Shlomo , Chris Skinner

Background: Researchers typically identify pregnancies in healthcare data based on observed outcomes (e.g., delivery). This outcome-based approach misses pregnancies that received prenatal care but whose outcomes were not recorded (e.g.,…

When data contains measurement errors, it is necessary to make assumptions relating the observed, erroneous data to the unobserved true phenomena of interest. These assumptions should be justifiable on substantive grounds, but are often…

机器学习 · 统计学 2020-12-24 Noam Finkelstein , Roy Adams , Suchi Saria , Ilya Shpitser

Incidence estimation of HIV infection can be performed using recent infection testing algorithm (RITA) results from a cross-sectional sample. This allows practitioners to understand population trends in the HIV epidemic without having to…

统计方法学 · 统计学 2023-09-13 Marlena Bannick , Deborah Donnell , Richard Hayes , Oliver Laeyendecker , Fei Gao

Binary data are used in a broad area of biological sciences. Using binary presence-absence data, we can evaluate species co-occurrences that help elucidate relationships among organisms and environments. To summarize similarity between…

统计方法学 · 统计学 2023-03-21 Neo Christopher Chung , Błażej Miasojedow , Michał Startek , Anna Gambin

This paper is concerned with identification, estimation, and specification testing in causal evaluation problems when data is selective and/or missing. We leverage recent advances in the literature on graphical methods to provide a unifying…

计量经济学 · 经济学 2023-08-10 Simon Calmar Andersen , Louise Beuchert , Phillip Heiler , Helena Skyt Nielsen

We introduce a self-censoring model for multivariate nonignorable nonmonotone missing data, where the missingness process of each outcome is affected by its own value and is associated with missingness indicators of other outcomes, while…

统计方法学 · 统计学 2022-10-03 Yilin Li , Wang Miao , Ilya Shpitser , Eric J. Tchetgen Tchetgen

PURPOSE: Clinical examinations are performed on the basis of necessity. However, our decisions to investigate and document are influenced by various other factors, such as workload and preconceptions. Data missingness patterns may contain…

应用统计 · 统计学 2019-12-19 Robert O'Shea

Targeted Maximum Likelihood Estimation (TMLE) is increasingly used for doubly robust causal inference, but how missing data should be handled when using TMLE with data-adaptive approaches is unclear. Based on the Victorian Adolescent Health…

Widely used methods for analyzing missing data can be biased in small samples. To understand these biases, we evaluate in detail the situation where a small univariate normal sample, with values missing at random, is analyzed using either…

统计理论 · 数学 2017-03-27 Paul T. von Hippel

The epidemic of HIV in Malawi started early and at its peak 15% of all adults were infected with HIV. Malawi is a low-income country and the cost of putting all HIV-positive people in Malawi onto ART, expressed as a percentage of the gross…

定量方法 · 定量生物学 2014-09-17 Brian G Williams

The attributable fraction among the exposed (\textbf{AF}$_e$), also known as the attributable risk or excess fraction among the exposed, is the proportion of disease cases among the exposed that could be avoided by eliminating the exposure.…

统计方法学 · 统计学 2024-12-30 Kan Chen , Jing Cheng , M. Elizabeth Halloran , Dylan S. Small

Background: Existing guidelines for handling missing data are generally not consistent with the goals of prediction modelling, where missing data can occur at any stage of the model pipeline. Multiple imputation (MI), often heralded as the…

统计方法学 · 统计学 2022-06-27 Rose Sisk , Matthew Sperrin , Niels Peek , Maarten van Smeden , Glen P. Martin