相关论文: Modeling generic aspects of ideal fibril formation

In a system of noisy self-propelled particles with interactions that favor directional alignment, collective motion will appear if the density of particles is beyond a critical density. Starting with a reduced model for collective motion,…

The use of reduced models for investigating the self-assembly dynamics underlying protein shell formation in spherical viruses is described. The spontaneous self-assembly of these polyhedral, supramolecular structures, in which icosahedral…

In spite of the large amount of existing neural models in the literature, there is a lack of a systematic review of the possible effect of choosing different initial conditions on the dynamic evolution of neural systems. In this short…

We propose a new method for modelling simple longitudinal data. We aim to do this in a flexible manner (without restrictive assumptions about the shapes of individual trajectories), while exploiting structural similarities between the…

We classify fibrations by integral plane projective rational quartic curves whose generic fibre is regular but admits a non-smooth point that is a canonical divisor. These fibrations can only exist in characteristic two. The geometric…

In structure-based models of proteins, one often assumes that folding is accomplished when all contacts are established. This assumption may frequently lead to a conceptual problem that folding takes place in a temperature region of very…

Granular materials such as sand, powders, foams etc. are ubiquitous in our daily life, as well as in industrial and geotechnical applications. Although these disordered systems form stable structures if unperturbed, in practice they do…

The basic ingredients of models for the internal dynamics of globular clusters are reviewed, with an emphasis on the description of equilibrium configurations. The development of progressive complexity in the models is traced, concentrating…

We demonstrate that internal pivot-like defects, arising from rigor mutant motor proteins that bind without stepping, fundamentally reshape the dynamics of semiflexible filaments in two-dimensional motility assays. Using large-scale…

The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…

Let M be a filtered module. Some properties of elements of M are "generic" in the following sense: (being open/stable) if an element z of M has a property P then any approximation of z has P; (being dense) any element of M is approximated…

Collagen fibrils are the most important structural component of tendons. Their crimped structure and parallel arrangement within the tendon lead to a distinctive non-linear stress-strain curve when a tendon is stretched. Microstructural…

We study the nucleation and development of crack patterns in thin composite fibers under tension in this work. A fiber comprises an elastic core and an outer layer of a weaker brittle material. In recent tensile experiments on such…

Particle physics has evolved a coherent model that characterizes forces and particles at the most elementary level. This Standard Model, built from many theoretical and experimental studies, is in excellent accord with almost all current…

A simple method to get all main characteristics of nucleation process is proposed. The advantage of this method is an applicability to situations with non-linear behavior in time of effective external source of vapor. It is important…

The classical picture of a star-forming filament is a near-equilibrium structure, with collapse dependent on its gravitational criticality. Recent observations have complicated this picture, revealing filaments as a mess of apparently…

Novel numerical techniques, validated by an analysis of barnase and chymotrypsin inhibitor, are used to elucidate the paramount role played by the geometry of the protein backbone in steering the folding to the correct native state. It is…

It is shown that diffusion-limited classical nucleation theory (CNT) can be recovered as a simple limit of the recently proposed dynamical theory of nucleation based on fluctuating hydrodynamics (Lutsko, JCP 136, 034509 (2012)). The same…

Aggregation phenomena are ubiquitous in nature, encompassing out-of-equilibrium processes of fractal pattern formation, important in many areas of science and technology. Despite their simplicity, foundational models such as…

The functioning of machines typically requires a concerted action of their parts. This requirement also holds for molecular motors that drive vital cellular processes and imposes constraints on their conformational changes as well as the…