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Maximum likelihood estimation (MLE) methods are widely used for evolutionary tree. As evolutionary tree is not a smooth parameter, the consistency of its MLE has been a topic of debate. It has been noted without proof that the classical…

种群与进化 · 定量生物学 2014-05-06 Arindam RoyChoudhury

We consider the problem of adaptation to the margin in binary classification. We suggest a penalized empirical risk minimization classifier that adaptively attains, up to a logarithmic factor, fast optimal rates of convergence for the…

统计理论 · 数学 2007-06-13 A. B. Tsybakov , S. A. van de Geer

Classification of gene trees is an important task both in the analysis of multi-locus phylogenetic data, and assessment of the convergence of Markov Chain Monte Carlo (MCMC) analyses used in Bayesian phylogenetic tree reconstruction. The…

组合数学 · 数学 2024-06-10 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

Selective inference is considered for testing trees and edges in phylogenetic tree selection from molecular sequences. This improves the previously proposed approximately unbiased test by adjusting the selection bias when testing many trees…

应用统计 · 统计学 2019-05-27 Hidetoshi Shimodaira , Yoshikazu Terada

Probability estimation of tree topologies is one of the fundamental tasks in phylogenetic inference. The recently proposed subsplit Bayesian networks (SBNs) provide a powerful probabilistic graphical model for tree topology probability…

种群与进化 · 定量生物学 2024-09-10 Tianyu Xie , Musu Yuan , Minghua Deng , Cheng Zhang

Phylogenetic networks extend phylogenetic trees to allow for modeling reticulate evolutionary processes such as hybridization. They take the shape of a rooted, directed, acyclic graph, and when parameterized with evolutionary parameters,…

种群与进化 · 定量生物学 2018-08-28 R. A. L. Elworth , H. A. Ogilvie , J. Zhu , L. Nakhleh

Estimation in generalized linear models (GLM) is complicated by the presence of constraints. One can handle constraints by maximizing a penalized log-likelihood. Penalties such as the lasso are effective in high dimensions, but often lead…

机器学习 · 统计学 2017-11-07 Jason Xu , Eric C. Chi , Kenneth Lange

In high-dimensional data analysis, penalized likelihood estimators are shown to provide superior results in both variable selection and parameter estimation. A new algorithm, APPLE, is proposed for calculating the Approximate Path for…

机器学习 · 统计学 2013-05-07 Yi Yu , Yang Feng

The architecture of eukaryotic coding genes allows the production of several different protein isoforms by genes. Current gene phylogeny reconstruction methods make use of a single protein product per gene, ignoring information on…

数据结构与算法 · 计算机科学 2017-07-05 Esaie Kuitche , Manuel Lafond , Aïda Ouangraoua

A major task of evolutionary biology is the reconstruction of phylogenetic trees from molecular data. The evolutionary model is given by a Markov chain on a tree. Given samples from the leaves of the Markov chain, the goal is to reconstruct…

概率论 · 数学 2011-09-30 Constantinos Daskalakis , Elchanan Mossel , Sebastien Roch

Random forests remain among the most popular off-the-shelf supervised machine learning tools with a well-established track record of predictive accuracy in both regression and classification settings. Despite their empirical success as well…

机器学习 · 统计学 2020-09-15 Lucas Mentch , Siyu Zhou

Recursive decision trees are widely used to estimate heterogeneous causal treatment effects in experimental and observational studies. These methods are typically implemented using CART-type recursive partitioning and are often viewed as…

统计理论 · 数学 2026-03-19 Matias D. Cattaneo , Jason M. Klusowski , Ruiqi Rae Yu

A weighted recursive tree is an evolving tree in which vertices are assigned random vertex-weights and new vertices connect to a predecessor with a probability proportional to its weight. Here, we study the maximum degree and near-maximum…

概率论 · 数学 2023-01-31 Laura Eslava , Bas Lodewijks , Marcel Ortgiese

A consensus tree is a phylogenetic tree that synthesizes a given collection of phylogenetic trees, all of which share the same leaf labels but may have different topologies, typically obtained through bootstrapping. Our research focuses on…

种群与进化 · 定量生物学 2025-08-13 Elio Torquet , Jesper Jansson , Nadia Tahiri

Connected acyclic graphs (trees) are data objects that hierarchically organize categories. Collections of trees arise in a diverse variety of fields, including evolutionary biology, public health, machine learning, social sciences and…

统计方法学 · 统计学 2025-12-01 Maria Alejandra Valdez Cabrera , Amy D Willis , Armeen Taeb

Recent theoretical work has demonstrated that Neighbor Joining applied to concatenated DNA sequences is a statistically consistent method of species tree reconstruction. This brief note compares the accuracy of this approach to other…

种群与进化 · 定量生物学 2016-12-07 Joseph Rusinko , Matthew McPartlon

Bayesian inference with empirical likelihood faces a challenge as the posterior domain is a proper subset of the original parameter space due to the convex hull constraint. We propose a regularized exponentially tilted empirical likelihood…

统计方法学 · 统计学 2026-04-23 Eunseop Kim , Steven N. MacEachern , Mario Peruggia

The ancestral maximum-likelihood and phylogeography problems are two fundamental problems involving evolutionary studies. The ancestral maximum-likelihood problem involves identifying a rooted tree alongside internal node sequences that…

数据结构与算法 · 计算机科学 2023-08-15 Mohammad-Hadi Foroughmand-Araabi , Sama Goliaei , Kasra Alishahi

The generalized estimating equation (GEE) method is a popular tool for longitudinal data analysis. However, GEE produces biased estimates when the outcome of interest is associated with cluster size, a phenomenon known as informative…

统计方法学 · 统计学 2025-01-03 Yue Ma , Haofeng Wang , Xuejun Jiang

Much evidence from biological theory and empirical data indicates that, gene tree, phylogenetic trees reconstructed from different genes (loci), do not have to have exactly the same tree topologies. Such incongruence between gene trees…

种群与进化 · 定量生物学 2023-07-13 Ruriko Yoshida , David Barnhill , Keiji Miura , Daniel Howe