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The theoretical formulation of driven polymer translocation through nanopores is complicated by the combination of the pore electrohydrodynamics and the nonequilibrium polymer dynamics originating from the conformational polymer…

软凝聚态物质 · 物理学 2019-01-15 Sahin Buyukdagli , Jalal Sarabadani , Tapio Ala-Nissila

Polymer solutions subject to pressure driven flow and in nanoscale slit pores are systematically investigated using the dissipative particle dynamics approach. We investigated the effect of molecular weight, polymer concentration and flow…

软凝聚态物质 · 物理学 2015-06-25 J. A. Millan , W. Jiang , M. Laradji , Y. Wang

We investigate the dynamics of polymer translocation through a nanopore using two-dimensional Langevin dynamics simulations. In the absence of external driving force, we consider a polymer which is initially placed in the middle of the pore…

软凝聚态物质 · 物理学 2007-05-23 Ilkka Huopaniemi , Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying

We suggest a theoretical description of the force-induced translocation dynamics of a polymer chain through a nanopore. Our consideration is based on the tensile (Pincus) blob picture of a pulled chain and the notion of propagating front of…

软凝聚态物质 · 物理学 2012-04-17 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

The motion of polymers with inhomogeneous structure through nanopores is discussed theoretically. Specifically, we consider the translocation dynamics of polymers consisting of double-stranded and single-stranded blocks. Since only the…

统计力学 · 物理学 2009-11-11 Stanislav Kotsev , Anatoly B. Kolomeisky

We consider the passage of long polymers of length N through a hole in a membrane. If the process is slow, it is in principle possible to focus on the dynamics of the number of monomers s on one side of the membrane, assuming that the two…

软凝聚态物质 · 物理学 2009-11-10 Yacov Kantor , Mehran Kardar

We present a theoretical description of the dynamics of a semi-flexible polymer being pulled through a nanopore by an external force acting at the pore. Our theory is based on the tensile blob picture of Pincus in which the front of the…

统计力学 · 物理学 2015-09-16 Pui-Man Lam , Yi Zhen

Force-driven translocation of a macromolecule through a nanopore is investigated by taking into account the monomer-pore friction as well as the "crowding" of monomers on the {\it trans} - side of the membrane which counterbalance the…

软凝聚态物质 · 物理学 2014-10-06 Johan L. A. Dubbeldam , V. G. Rostiashvili , T. A. Vilgis

Polymers in a turbulent flow are subject to intense strain, which can cause their scission and thereby limit the experimental study and application of phenomena such as turbulent drag reduction and elastic turbulence. In this paper, we…

流体动力学 · 物理学 2021-02-17 Dario Vincenzi , Takeshi Watanabe , Samriddhi Sankar Ray , Jason R. Picardo

We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory…

软凝聚态物质 · 物理学 2018-02-14 Jalal Sarabadani , Bappa Ghosh , Srabanti Chaudhury , Tapio Ala-Nissila

We investigate several scaling properties of a translocating homopolymer through a thin pore driven by an external field present inside the pore only using Langevin Dynamics (LD) simulation in three dimension (3D). Specifically motivated by…

We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent, using an innovative multi-scale methodology which treats the biopolymer at the microscopic scale as combined with a…

计算物理 · 物理学 2008-02-27 Massimo Bernaschi , Simone Melchionna , Sauro Succi , Maria Fyta , Efthimios Kaxiras

Force induced stretching of polymers is important in a variety of contexts. We have used theory and simulations to describe the response of homopolymers, with $N$ monomers, to force ($f$) in good and poor solvents. In good solvents and for…

软凝聚态物质 · 物理学 2009-11-13 Greg Morrison , Changbong Hyeon , N. M. Toan , Bae-Yeun Ha , D. Thirumalai

Sensitive sequencing of biopolymers by nanopore-based translocation techniques requires extension of the time spent by the molecule in the pore. We develop an electrostatic theory of polymer translocation to show that the translocation time…

软凝聚态物质 · 物理学 2018-11-12 Sahin Buyukdagli , Jalal Sarabadani , Tapio Ala-Nissila

Here using LAMMPS molecular dynamics (MD) software, we simulate polymer translocation in 2 dimensions. We do the simulations for weak and moderate forces and for different pore diameters. Our results show that in both non-equilibrium and…

计算物理 · 物理学 2018-04-26 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

We study the translocation of a semiflexible polymer through a conical channel with attractive surface interactions and a driving force which varies spatially inside the channel. Using the results of the translocation dynamics of a flexible…

软凝聚态物质 · 物理学 2022-11-15 Andri Sharma , Rajeev Kapri , Abhishek Chaudhuri

We present event distributions for the polymer translocation obtained by extensive Langevin dynamics simulations. Such distributions have not been reported previously and they provide new understanding of the stochastic characteristics of…

软凝聚态物质 · 物理学 2012-04-13 R. P. Linna , K. Kaski

We develop a theory for polymer translocation driven by a time-dependent force through an oscillating nanopore. To this end, we extend the iso-flux tension propagation theory (IFTP) [Sarabadani \textit{et al., J. Chem. Phys.}, 2014,…

统计力学 · 物理学 2015-09-02 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

We employ a multiscale approach to model the translocation of biopolymers through nanometer size pores. Our computational scheme combines microscopic Langevin molecular dynamics (MD) with a mesoscopic lattice Boltzmann (LB) method for the…

生物物理 · 物理学 2011-11-10 Maria Fyta , Simone Melchionna , Efthimios Kaxiras , Sauro Succi

We study the driven translocation of polymers under time-dependent driving forces using $N$-particle Langevin dynamics simulations. We consider the force to be either sinusoidally oscillating in time or dichotomic noise with exponential…

软凝聚态物质 · 物理学 2015-06-12 Timo Ikonen , Jaeoh Shin , Tapio Ala-Nissila , Wokyung Sung