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The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

The properties of functional brain networks strongly depend on how their nodes are chosen. Commonly, nodes are defined by Regions of Interest (ROIs), pre-determined groupings of fMRI measurement voxels. Earlier, we have demonstrated that…

神经元与认知 · 定量生物学 2019-11-25 Elisa Ryyppö , Enrico Glerean , Elvira Brattico , Jari Saramäki , Onerva Korhonen

Brain connectome analysis commonly compresses high-resolution brain scans (typically composed of millions of voxels) down to only hundreds of regions of interest (ROIs) by averaging within-ROI signals. This huge dimension reduction improves…

统计方法学 · 统计学 2025-03-25 Tong Lu , Yuan Zhang , Peter Kochunov , Elliot Hong , Shuo Chen

Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

神经元与认知 · 定量生物学 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

In recent years, graph neural networks (GNNs) have been widely applied in the analysis of brain fMRI, yet defining the connectivity between ROIs remains a challenge in noisy fMRI data. Among all approaches, Functional Connectome (FC) is the…

机器学习 · 计算机科学 2025-04-09 Jiyao Wang , Nicha C. Dvornek , Peiyu Duan , Lawrence H. Staib , Pamela Ventola , James S. Duncan

Functional Magnetic Resonance Imaging (fMRI) is a non-invasive technique for studying brain activity. During an fMRI session, the subject executes a set of tasks (task-related fMRI study) or no tasks (resting-state fMRI), and a sequence of…

图像与视频处理 · 电气工程与系统科学 2023-10-10 Christos Theodoropoulos , Christos Chatzichristos , Sabine Van Huffel

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

统计方法学 · 统计学 2016-03-22 Jichun Xie , Jian Kang

Imaging studies suggest that the functional connectivity patterns of resting state networks (RS-networks) reflect underlying structural connectivity (SC). If the connectome constrains how brain areas are functionally connected, the…

神经元与认知 · 定量生物学 2016-02-25 Andreas Spiegler , Enrique C. A. Hansen , Christophe Bernard , Anthony R. McIntosh , Viktor K. Jirsa

Resting State Networks (RSNs) of the brain extracted from Resting State functional Magnetic Resonance Imaging (RS-fMRI) are used in the pre-surgical planning to guide the neurosurgeon. This is difficult, though, as expert knowledge is…

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

应用统计 · 统计学 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Analysis of brain activity in resting-state is of fundamental importance in identifying functional characteristics of neuronal system. Although resting brain has been extensively investigated for low frequency synchrony between brain…

神经元与认知 · 定量生物学 2012-01-04 Shahab Kadkhodaeian Bakhtiari , Gholam-Ali Hossein-Zadeh

Brain network is an important tool for understanding the brain, offering insights for scientific research and clinical diagnosis. Existing models for brain networks typically primarily focus on brain regions or overlook the complexity of…

神经元与认知 · 定量生物学 2024-05-30 Haoyu Hu , Hongrun Zhang , Chao Li

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

神经元与认知 · 定量生物学 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of \emph{gradual and continuous} changes in the brain blood oxygenated…

神经元与认知 · 定量生物学 2011-07-25 Enzo Tagliazucchi , Pablo Balenzuela , Daniel Fraiman , Dante R. Chialvo

Graph-theoretical methods have rapidly become a standard tool in studies of the structure and function of the human brain. Whereas the structural connectome can be fairly straightforwardly mapped onto a complex network, there are more…

神经元与认知 · 定量生物学 2017-11-10 Tuomas Alakörkkö , Heini Saarimäki , Enrico Glerean , Jari Saramäki , Onerva Korhonen

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

计算机视觉与模式识别 · 计算机科学 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

机器学习 · 计算机科学 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

We construct embedded functional connectivity networks (FCN) from benchmark resting-state functional magnetic resonance imaging (rsfMRI) data acquired from patients with schizophrenia and healthy controls based on linear and nonlinear…

神经元与认知 · 定量生物学 2023-03-24 Ioannis Gallos , Evangelos Galaris , Constantinos Siettos

Predicting cognition from neuroimaging data in healthy individuals offers insights into the neural mechanisms underlying cognitive abilities, with potential applications in precision medicine and early detection of neurological and…

机器学习 · 计算机科学 2025-07-29 Jagruti Patel , Mikkel Schöttner , Thomas A. W. Bolton , Patric Hagmann

Standard fMRI connectivity analyses depend on aggregating the time series of individual voxels within regions of interest (ROIs). In certain cases, this spatial aggregation implies a loss of valuable functional and anatomical information…

神经元与认知 · 定量生物学 2019-08-12 Ruben Sanchez-Romero , Joseph D. Ramsey , Kun Zhang , Clark Glymour