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Neural connectomics has begun producing massive amounts of data, necessitating new analysis methods to discover the biological and computational structure. It has long been assumed that discovering neuron types and their relation to…

神经元与认知 · 定量生物学 2014-07-17 Eric Jonas , Konrad Kording

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

神经元与认知 · 定量生物学 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

In this work, we developed new mathematical methods for analyzing network topology and applied these methods to the analysis of brain networks. More specifically, we rigorously developed quantitative methods based on complexes constructed…

神经元与认知 · 定量生物学 2026-04-28 Heitor Baldo

Memory is an important cognitive function for humans. How a brain with such a small power can complete such a complex memory function, the working mechanism behind this is undoubtedly fascinating. Engram theory views memory as the…

分布式、并行与集群计算 · 计算机科学 2023-07-13 Hui Wei , Weihua Miao , Fushun Li

We advance our approach of analyzing the dynamics of interacting complex systems with the nonlinear dynamics of interacting nonlinear elements. We replace the widely used lattice-like connection topology of cellular neural networks (CNN) by…

神经元与认知 · 定量生物学 2016-10-10 Henning Dickten , Christian E. Elger , Klaus Lehnertz

Understanding the mechanisms of neural communication in large-scale brain networks remains a major goal in neuroscience. We investigated whether navigation is a parsimonious routing model for connectomics. Navigating a network involves…

神经元与认知 · 定量生物学 2018-06-05 Caio Seguin , Martijn P. van den Heuvel , Andrew Zalesky

Understanding how biological and artificial neural networks implement computation from connectivity is a central problem in neuroscience and machine learning. In neural systems, structural and functional connectivity are known to diverge,…

神经与进化计算 · 计算机科学 2026-05-07 Jatin Sharma , Dan F. M Goodman , Danyal Akarca

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

神经元与认知 · 定量生物学 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

应用统计 · 统计学 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

Dynamics and function of neuronal networks are determined by their synaptic connectivity. Current experimental methods to analyze synaptic network structure on the cellular level, however, cover only small fractions of functional neuronal…

神经元与认知 · 定量生物学 2015-07-28 Yury V. Zaytsev , Abigail Morrison , Moritz Deger

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

计算机视觉与模式识别 · 计算机科学 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

In the study of biological networks, one of the major challenges is to understand the relationships between network structure and dynamics. In this paper, we model in vitro cortical neuronal cultures as stochastic dynamical systems and…

神经元与认知 · 定量生物学 2022-05-04 Chumin Sun , K. C. Lin , C. Y. Yeung , Emily S. C. Ching , Yu-Ting Huang , Pik-Yin Lai , C. K. Chan

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

机器学习 · 计算机科学 2024-02-13 Lorenzo Giusti

Brain development during adolescence is marked by substantial changes in brain structure and function, leading to a stable network topology in adulthood. However, most prior work has examined the data through the lens of brain areas…

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

无序系统与神经网络 · 物理学 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

神经与进化计算 · 计算机科学 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

统计计算 · 统计学 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

The brain can be regarded as a network: a connected system where nodes, or units, represent different specialized regions and links, or connections, represent communication pathways. From a functional perspective communication is coded by…

神经元与认知 · 定量生物学 2014-09-10 Fabrizio De Vico Fallani , Jonas Richiardi , Mario Chavez , Sophie Achard

This paper describes how realistic neuromorphic networks can have their connectivity fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the two-dimensional…

无序系统与神经网络 · 物理学 2007-05-23 Luciano da Fontoura Costa , Marconi Soares Barbosa

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar