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Grid cells play a principal role in enabling mammalian cognitive representations of ambient environments. The key property of these cells -- the regular arrangement of their firing fields -- is commonly viewed as means for establishing…

神经元与认知 · 定量生物学 2022-08-30 Yuri Dabaghian

The grid cells (GCs) of the medial entorhinal cortex (MEC) and place cells (PCs) of the hippocampus are key elements of the brain network for the metric representation of space. Currently, any of the existing theoretical models can explain…

神经元与认知 · 定量生物学 2015-07-01 Andrey Stepanyuk

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

神经元与认知 · 定量生物学 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

Research on network mechanisms and coding properties of grid cells assume that the firing rate of a grid cell in each of its fields is the same. Furthermore, proposed network models predict spatial regularities in the firing of inhibitory…

神经元与认知 · 定量生物学 2017-01-19 Benjamin Dunn , Daniel Wennberg , Ziwei Huang , Yasser Roudi

About a decade ago grid cells were discovered in the medial entorhinal cortex of rat. Their peculiar firing patterns, which correlate with periodic locations in the environment, led to early hypothesis that grid cells may provide some form…

神经元与认知 · 定量生物学 2018-10-18 Jochen Kerdels , Gabriele Peters

The grid cells discovered in the rodent medial entorhinal cortex have been proposed to provide a metric for Euclidean space, possibly even hardwired in the embryo. Yet one class of models describing the formation of grid unit selectivity is…

神经元与认知 · 定量生物学 2015-02-10 Eugenio Urdapilleta , Francesca Troiani , Federico Stella , Alessandro Treves

Grid cells in the entorhinal cortex fire when animals that are exploring a certain region of space occupy the vertices of a triangular grid that spans the environment. Different neurons feature triangular grids that differ in their…

神经元与认知 · 定量生物学 2017-01-04 Alessandro Sanzeni , Vijay Balasubramanian , Guido Tiana , Massimo Vergassola

Grid cells, discovered more than a decade ago [5], are neurons in the brain of mammals that fire when the animal is located near certain specific points in its familiar terrain. Intriguingly, these points form, for a single cell, a…

神经元与认知 · 定量生物学 2016-06-16 Christos H. Papadimitriou

Space is represented in the mammalian brain by the activity of hippocampal place cells as well as in their spike-timing correlations. Here we propose a theory how this temporal code is transformed to spatial firing rate patterns via…

神经元与认知 · 定量生物学 2017-08-02 Mauro M. Monsalve-Mercado , Christian Leibold

The spatial responses of many of the cells recorded in all layers of rodent medial entorhinal cortex (mEC) show a triangular grid pattern, and once established might be based in part on path-integration mechanisms. Grid axes are tightly…

神经元与认知 · 定量生物学 2012-03-20 Bailu Si , Emilio Kropff , Alessandro Treves

This paper investigates whether the hexagonal structure of grid cells provides any performance benefits or if it merely represents a biologically convenient configuration. Utilizing the Vector-HaSH content addressable memory model as a…

神经元与认知 · 定量生物学 2024-10-17 Taahaa Mir , Peipei Yao , Kateri Duranceau , Isabeau Prémont-Schwarz

Grid cells in the medial entorhinal cortex and place cells in the hippocampus together support spatial navigation. The two regions are reciprocally connected, and there is a chicken-and-egg problem for how both arise and reinforce each…

神经元与认知 · 定量生物学 2026-05-21 Zhaoze Wang , Genela Morris , Dori Derdikman , Pratik Chaudhari , Vijay Balasubramanian

In this paper we explain the strikingly regular activity of the 'grid' cells in rodent dorsal medial entorhinal cortex (dMEC) and the spatially localized activity of the hippocampal place cells in CA3 and CA1 by assuming that the…

神经元与认知 · 定量生物学 2008-04-22 Andras Lorincz , Melinda Kiszlinger , Gabor Szirtes

Grid cells in the entorhinal cortex encode the position of an animal in its environment using spatially periodic tuning curves of varying periodicity. Recent experiments established that these cells are functionally organized in discrete…

神经元与认知 · 定量生物学 2016-01-13 Noga Weiss Mosheiff , Haggai Agmon , Avraham Moriel , Yoram Burak

Grid cells in the entorhinal cortex, together with head direction, place, speed and border cells, are major contributors to the organization of spatial representations in the brain. In this work we introduce a novel theoretical and…

神经元与认知 · 定量生物学 2019-07-25 Fabio Anselmi , Micah M. Murray , Benedetta Franceschiello

Grid cells in the brain respond when an animal occupies a periodic lattice of "grid fields" during spatial navigation. The grid scale varies along the dorso-ventral axis of the entorhinal cortex. We propose that the grid system minimizes…

神经元与认知 · 定量生物学 2018-05-14 Xue-Xin Wei , Jason Prentice , Vijay Balasubramanian

The hippocampus encodes space through a striking gradient of place field sizes along its dorsal-ventral axis, yet the principles generating this continuous gradient from discrete grid cell inputs remain debated. We propose a unified…

神经元与认知 · 定量生物学 2025-06-06 Shujun Zhou , Guozhang Chen

What sort of grid cells do we expect to see in bats exploring a three-dimensional environment? How long will it take for them to emerge? We address these questions within our self-organization model based on firing-rate adaptation. The…

神经元与认知 · 定量生物学 2014-12-03 Federico Stella , Alessandro Treves

We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a generalized linear model (kinetic Ising model), study their functional…

神经元与认知 · 定量生物学 2015-06-19 Benjamin Dunn , Maria Mørreaunet , Yasser Roudi

Place cells in the hippocampus are active when an animal visits a certain location (referred to as a place field) within an environment. Grid cells in the medial entorhinal cortex (MEC) respond at multiple locations, with firing fields that…

神经元与认知 · 定量生物学 2018-05-17 David M. Schwartz , O. Ozan Koyluoglu
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