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In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…

偏微分方程分析 · 数学 2022-05-25 Slah Eddin Ben Abdeljalil , Atef Ben Essid , Saloua Mani Aouadi

We investigate aging continuous time random walks (ACTRW), introduced by Monthus and Bouchaud [{\em J. Phys. A} {\bf 29}, 3847 (1996)]. Statistical behaviors of the displacement of the random walker ${\bf r}={\bf r}(t) - {\bf r}(0)$ in the…

统计力学 · 物理学 2009-11-07 Eli Barkai , Yuan-Chung Cheng

The phenomenon of spatial clustering induced by death and reproduction in a population of anomalously diffusing individuals is studied analytically. The possibility of social behaviors affecting the migration strategies has been taken into…

种群与进化 · 定量生物学 2015-05-30 Piero Olla

It is widely recognized that reciprocal interactions between cells and their microenvironment, via mechanical forces and biochemical signaling pathways, regulate cell behaviors during normal development, homeostasis and disease progression…

生物物理 · 物理学 2024-12-05 Nonthakorn Olaranont , Chaozhen Wei , John Lowengrub , Min Wu

Cell growth in size is a complex process coordinated by intrinsic and environmental signals. In a recent work [Tzur et al., Science, 2009, 325:167-171], size distributions in an exponentially growing population of mammalian cells were used…

细胞行为 · 定量生物学 2015-06-16 Yucheng Hu , Tianqi Zhu

We study the Tree Builder Random Walk: a randomly growing tree, built by a walker as she is walking around the tree. Namely, at each time $n$, she adds a leaf to her current vertex with probability $p_n \asymp n^{-\gamma}$, $\gamma\in…

概率论 · 数学 2024-12-09 Janos Engländer , Giulio Iacobelli , Gábor Pete , Rodrigo Ribeiro

The nervous system is today recognized to play an important role in the development of cancer. Indeed, neurons extend long processes (axons) that grow and infiltrate tumors in order to regulate the progression of the disease in a positive…

动力系统 · 数学 2022-05-25 Sophie Chauvet , Florence Hubert , Fanny Mann , Mathieu Mezache

Continuous-time random walks (CTRWs) on discrete state spaces, ranging from regular lattices to complex networks, are ubiquitous across physics, chemistry, and biology. Models with coarse-grained states, for example those employed in…

统计力学 · 物理学 2015-12-03 Michael Manhart , Willow Kion-Crosby , Alexandre V. Morozov

This paper derives and analyzes continuous time random walk (CTRW) models in radial flow geometries for the quantification of non-local solute transport induced by heterogeneous flow distributions and by mobile-immobile mass transfer…

流体动力学 · 物理学 2016-11-28 Marco Dentz , Peter K. Kang , Tanguy le Borgne

In this paper, we introduce a novel framework using inhomogeneous Branching Random Walks (BRWs) to model growth processes, specifically introducing genealogy-dependence in branching rates and displacement distributions to model phenomena…

种群与进化 · 定量生物学 2025-12-11 Lauren Ajax , Beatrice Durham , Pratima Hebbar , Cade Johnson , Jiayi Zhang

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

组织与器官 · 定量生物学 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

An intense research on financial market microstructure is presently in progress. Continuous time random walks (CTRWs) are general models capable to capture the small-scale properties that high frequency data series show. The use of CTRW…

物理与社会 · 物理学 2008-12-02 Miquel Montero , Jaume Masoliver

Plant hormone auxin has critical roles in plant growth, dependent on its heterogeneous distribution in plant tissues. Exactly how auxin transport and developmental processes such as growth coordinate to achieve the precise patterns of auxin…

组织与器官 · 定量生物学 2019-11-14 Henry R. Allen , Mariya Ptashnyk

The combined Continuous Time Random Walk (CTRW) in position and momentum space is introduced, in the form of two coupled integral equations that describe the evolution of the probability distribution for finding a particle at a certain…

混沌动力学 · 物理学 2007-10-29 H. Isliker

In this paper we present a study of local dynamics of the growth of cancer tumor and healthy cells considering the presence of nutrients in the system. We also analyze the evolution of system if we take indirectly into account the level of…

生物物理 · 物理学 2019-01-29 Cristian C. Pérez Águila , Maura Cárdenas G. , J. Fernando Rojas

Recent findings suggest that processes such as the electronic energy transfer through the photosynthetic antenna display quantal features, aspects known from the dynamics of charge carriers along polymer backbones. Hence, in modeling energy…

量子物理 · 物理学 2015-05-13 Elena Agliari , Oliver Muelken , Alexander Blumen

We investigate the dynamics of a particle executing a general Continuous Time Random Walk (CTRW) in three dimensions under the influence of arbitrary time-varying external fields. Contrary to the general approach in recent works, our method…

统计力学 · 物理学 2011-12-15 Shovan Dutta , Subhankar Ray , J. Shamanna

Continuous time random walks (CTRWs) are versatile models for anomalous diffusion processes that have found widespread application in the quantitative sciences. Their scaling limits are typically non-Markovian, and the computation of their…

概率论 · 数学 2014-07-25 Mark M. Meerschaert , Peter Straka

Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis.…

概率论 · 数学 2010-07-15 Rick Durrett , Jasmine Foo , Kevin Leder , John Mayberry , Franziska Michor

Stochastic resonance induced by external factor is considering to investigate the complex dynamics of tumor. The surrounding environment and the treatment effects on the tumor growth are considered as additive and multiplicative noises in…

细胞行为 · 定量生物学 2017-07-18 Najmeh Sadat Mirian