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Numerical simulations of cardiovascular mass transport pose significant challenges due to the wide range of P\'eclet numbers and backflow at Neumann boundaries. In this paper we present and discuss several numerical tools to address these…

A new method for analyzing arterial blood pressure is presented in this report. The technique is based on the scattering transform and consists in solving the spectral problem associated to a one-dimensional Schr\"odinger operator with a…

Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…

计算机视觉与模式识别 · 计算机科学 2023-05-31 Ziyu Ni , Linda Wei , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

We investigate flow of incompressible fluid in a cylindrical tube with elastic walls. The radius of the tube may change along its length. The discussed problem is connected to the blood flow in large human arteries and especially to…

流体动力学 · 物理学 2015-09-30 Zlatinka I. Dimitrova

The present focus of heart flow studies is largely based on flow within the left ventricle and how this flow changes when subject to disease. However, despite recent advancements, a simple tractable model of even healthy left ventricular…

流体动力学 · 物理学 2019-03-18 Giuseppe Di Labbio , Lyes Kadem

There is currently limited understanding of the role played by haemodynamic forces on the processes governing vascular development. One of many obstacles to be overcome is being able to measure those forces, at the required resolution…

Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…

医学物理 · 物理学 2022-01-03 Stefania Scarsoglio , Luca Ridolfi

Many numerical studies of blood flow impose a rigid wall assumption due to the simplicity of its implementation compared to a full coupling to a solid mechanics model. In this paper, we present a localised method for incorporating the…

流体动力学 · 物理学 2021-08-20 J. W. S. McCullough , P. V. Coveney

In this paper, we deal with the problem of determining perfectly insulating regions (cavities) from one boundary measurement in a nonlinear elliptic equation arising from cardiac electrophysiology. Based on the results obtained in [9] we…

偏微分方程分析 · 数学 2022-08-09 Elena Beretta , M. Cristina Cerutti , Dario Pierotti , Luca Ratti

There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…

流体动力学 · 物理学 2018-03-12 Fardin Khalili , Peshala T. Gamage , Hansen Mansy

Background: Computational fluid dynamics (CFD) is increasingly used to assess blood flow conditions in patients with congenital heart disease (CHD). This requires patient-specific anatomy, usually obtained from segmented 3D cardiovascular…

The increasing application of cardiorespiratory simulations for diagnosis and surgical planning necessitates the development of computational methods significantly faster than the current technology. To achieve this objective, we leverage…

数值分析 · 数学 2024-03-21 Mahdi Esmaily , Dongjie Jia

A data-driven Reduced Order Model (ROM) based on a Proper Orthogonal Decomposition - Radial Basis Function (POD-RBF) approach is adopted in this paper for the analysis of blood flow dynamics in a patient-specific case of Atrial Fibrillation…

Morphological analysis and identification of pathologies in the aorta are important for cardiovascular diagnosis and risk assessment in patients. Manual annotation is time-consuming and cumbersome in CT scans acquired without contrast…

计算机视觉与模式识别 · 计算机科学 2018-10-16 Julia M. H. Noothout , Bob D. de Vos , Jelmer M. Wolterink , Ivana Isgum

Background and Objective: Event-based analog-to-digital converters allow for sparse bio-signal acquisition, enabling local sub-Nyquist sampling frequency. However, aggressive event selection can cause the loss of important bio-markers, not…

信号处理 · 电气工程与系统科学 2022-07-06 Silvio Zanoli , Tomas Teijeiro , Giovanni Ansaloni , David Atienza

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

软凝聚态物质 · 物理学 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

计算工程、金融与科学 · 计算机科学 2023-03-27 Alberto Zingaro , Christian Vergara , Luca Dede' , Francesco Regazzoni , Alfio Quarteroni

The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…

流体动力学 · 物理学 2024-02-21 Hashnayne Ahmed , Chinmayee Podder

It is well known that in the computational fluid dynamics simulations related to the cardiovascular system the enforcement of outflow boundary conditions is a crucial point. In fact, they highly affect the computed flow and a wrong setup…

流体动力学 · 物理学 2025-03-05 Zahra Mirzaiyan , Michele Girfoglio , Gianluigi Rozza

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…

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