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相关论文: Numerical study of DNA denaturation with self-avoi…

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We study numerically the effect of sequence heterogeneity on the thermodynamic properties of a Poland-Scheraga model for DNA denaturation taking into account self-avoidance, i.e. with exponent c_p=2.15 for the loop length probability…

无序系统与神经网络 · 物理学 2016-05-06 Barbara Coluzzi , Edouard Yeramian

We numerically study the binary disordered Poland-Scheraga model of DNA denaturation, in the regime where the pure model displays a first order transition (loop exponent $c=2.15>2$). We use a Fixman-Freire scheme for the entropy of loops…

无序系统与神经网络 · 物理学 2007-05-23 Thomas Garel , Cecile Monthus

According to recent progresses in the finite size scaling theory of disordered systems, thermodynamic observables are not self-averaging at critical points when the disorder is relevant in the Harris criterion sense. This lack of…

无序系统与神经网络 · 物理学 2007-05-23 Cecile Monthus , Thomas Garel

The Poland--Scheraga model, introduced in the 1970's, is a reference model to describe the denaturation transition of DNA. More recently, it has been generalized in order to allow for asymmetry in the strands lengths and in the formation of…

概率论 · 数学 2024-06-18 Quentin Berger , Alexandre Legrand

We compare results of previous simulations of a simple model of DNA denaturation to the predictions of the Poland-Scheraga model. Concentrating on the critical region of the latter model we calculate both thermodynamic quantities and the…

统计力学 · 物理学 2007-05-23 Lothar Schäfer

The Poland-Scheraga model is a celebrated model for the denaturation transition of DNA, which has been widely used in the bio-physical literature to study, and investigated by mathematicians. In the original model, only opposite bases of…

概率论 · 数学 2020-11-05 Alexandre Legrand

Poland-Scheraga models were introduced to describe the DNA denaturation transition. We give a rigorous and refined discussion of a family of these models. We derive possible scaling functions in the neighborhood of the phase transition…

统计力学 · 物理学 2008-08-28 C. Richard , A. J. Guttmann

When double-stranded DNA molecules are heated, or exposed to denaturing agents, the two strands get separated. The statistical physics of this process has a long history, and is commonly described in term of the Poland-Scheraga (PS) model.…

生物大分子 · 定量生物学 2015-09-21 Michaela Reiter-Schad , Erik Werner , Jonas O. Tegenfeldt , Bernhard Mehlig , Tobias Ambjornsson

We generalize the Poland-Scheraga (PS) model to the case of a circular DNA, taking into account the twisting of the two strains around each other. Guided by recent single-molecule experiments on DNA strands, we assume that the torsional…

软凝聚态物质 · 物理学 2009-06-04 A. Kabakcioglu , E. Orlandini , D. Mukamel

The denaturation transition which takes place in circular DNA is analyzed by extending the Poland-Scheraga model to include the winding degrees of freedom. We consider the case of a homopolymer whereby the winding number of the double…

统计力学 · 物理学 2011-11-22 Amir Bar , Alkan Kabakçıoğlu , David Mukamel

We generalize the Poland-Scheraga model to consider DNA denaturation in the presence of an external stretching force. We demonstrate the existence of a force-induced DNA denaturation transition and obtain the temperature-force phase…

软凝聚态物质 · 物理学 2009-11-13 Andreas Hanke , Martha G. Ochoa , Ralf Metzler

We investigate the generalized Poland-Scheraga model, which is used in the bio-physical literature to model the DNA denaturation transition, in the case where the two strands are allowed to be non-complementary (and to have different…

概率论 · 数学 2018-07-31 Quentin Berger , Giambattista Giacomin , Maha Khatib

We study pairs of interacting self-avoiding walks on the 3d simple cubic lattice. They have a common origin and are allowed to overlap only at the same monomer position along the chain. The latter overlaps are indeed favored by an energetic…

软凝聚态物质 · 物理学 2009-10-31 Maria Serena Causo , Barbara Coluzzi , Peter Grassberger

The distance distribution between complementary base pairs of the two strands of a DNA molecule is studied near the melting transition. Scaling arguments are presented for a generalized Poland-Scheraga type model which includes…

统计力学 · 物理学 2009-11-07 M. Baiesi , E. Carlon , Y. Kafri , D. Mukamel , E. Orlandini , A. L. Stella

We numerically study the wetting (adsorption) transition of a polymer chain on a disordered substrate in 1+1 dimension.Following the Poland-Scheraga model of DNA denaturation, we use a Fixman-Freire scheme for the entropy of loops. This…

无序系统与神经网络 · 物理学 2007-05-23 Thomas Garel , Cecile Monthus

The Poland-Scheraga model for DNA denaturation, besides playing a central role in applications, has been widely studied in the physical and mathematical literature over the past decades. More recently a natural generalization has been…

概率论 · 数学 2017-03-31 Quentin Berger , Giambattista Giacomin , Maha Khatib

We discuss possible mechanisms that may impact the order of the transition between denaturated and bound DNA states and lead to changes in the scaling laws that govern conformational properties of DNA strands. To this end, we re-consider…

软凝聚态物质 · 物理学 2021-04-07 Yulian Honchar , Christian von Ferber , Yurij Holovatch

The denaturation transition of circular DNA is studied within a Poland-Scheraga type approach, generalized to account for the fact that the total linking number (LK), which measures the number of windings of one strand around the other, is…

统计力学 · 物理学 2015-06-05 Amir Bar , Alkan Kabakçıoğlu , David Mukamel

Using a field theory equivalent to a lattice version of the Poland-Scheraga (PS) model, the phase diagram for a long DNA molecule is derived in closed form. A one-loop renormalization group calculation for the generalized PS model with…

软凝聚态物质 · 物理学 2026-04-01 Richard Dengler

We study the large deviations of additive quantities, such as energy or current, in stochastic processes with intermittent reset. Via a mapping from a discrete-time reset process to the Poland-Scheraga model for DNA denaturation, we derive…

统计力学 · 物理学 2017-02-09 Rosemary J. Harris , Hugo Touchette
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