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Eukaryotic gene regulation is based on stochastic yet controlled promoter switching, during which genes transition between transcriptionally active and inactive states. Despite the molecular complexity of this process, recent studies reveal…

分子网络 · 定量生物学 2025-07-17 Benjamin Zoller , Alexis Bénichou , Thomas Gregor , Gašper Tkačik

The analytical treatment of nonlinear evolution of the shear-flow-modified current driven ion cyclotron instability and shear-flow-driven ion cyclotron kinetic instabilities of magnetic field--aligned plasma shear flow is presented.…

等离子体物理 · 物理学 2009-11-13 V. S. Mikhailenko , V. V. Mikhailenko , K. N. Stepanov , N. A. Azarenkov

This paper considers a leader-following formation control problem for heterogeneous, second-order, uncertain, input-affine, nonlinear multi-agent systems modeled by a directed graph. A tunable, three-layer neural network (NN) is proposed…

系统与控制 · 电气工程与系统科学 2024-04-24 Kiarash Aryankia , Rastko R. Selmic

A combined analytic and computational gyrokinetic approach is developed to address the question of the scaling of pedestal turbulent transport with arbitrary levels of $E \times B$ shear. Due to strong gradients and shaping in the pedestal,…

等离子体物理 · 物理学 2018-08-01 D. R. Hatch , R. D. Hazeltine , M. K. Kotschenreuther , S. M. Mahajan

Modeling fluid turbulence using a 'skeleton' of coherent structures has traditionally progressed by focusing on a few canonical experiments, such as pipe flow and Taylor-Couette flow. We here consider an alternative canonical experiment,…

流体动力学 · 物理学 2023-05-09 Adrien Lefauve , Miles M. P. Couchman

This paper presents a comprehensive experimental and numerical investigation into the control of boundary layers using porous bleed systems. The study focuses on both supersonic and subsonic flow regimes, as well as on the control of…

流体动力学 · 物理学 2023-12-06 Julian Giehler , Thibault Leudiere , Robert Soares Morgadinho , Pierre Grenson , Reynald Bur

Iterative optimization algorithms depend on access to information about the objective function. In a differentiable programming framework, this information, such as gradients, can be automatically derived from the computational graph. We…

最优化与控制 · 数学 2025-07-08 Vincent Roulet , Siddhartha Srinivasa , Maryam Fazel , Zaid Harchaoui

Turbulent flow over permeable interface is omnipresent featuring complex flow topology. In this work, a data driven, end to end machine learning model has been developed to model the turbulent flow in porous media. For the same, we have…

流体动力学 · 物理学 2023-11-28 Xu Chu , Sandeep Pandey

When an external field is applied across a liquid-crystal cell, the twist and tilt distributions cannot be calculated analytically and must be extracted numerically. In the standard approach, the Euler-Lagrange equations are derived from…

计算物理 · 物理学 2025-11-18 Alicia Sit , Francesco Di Colandrea , Alessio D'Errico , Ebrahim Karimi

We present a reformulation of unsteady turbulent flow simulations. The initial condition is relaxed and information is allowed to propagate both forward and backward in time. Simulations of chaotic dynamical systems with this reformulation…

流体动力学 · 物理学 2015-06-12 Qiqi Wang , Steven Gomez , Patrick Blonigan , Alastair Gregory , Elizabeth Qian

We propose a new application of random tensor theory to studies of non-linear random flows in many variables. Our focus is on non-linear resonant systems which often emerge as weakly non-linear approximations to problems whose linearized…

数学物理 · 物理学 2020-03-12 Stéphane Dartois , Oleg Evnin , Luca Lionni , Vincent Rivasseau , Guillaume Valette

Dynamic control is emerging as an effective methodology for operating stormwater systems under stress from rapidly evolving weather patterns. Informed by rainfall predictions and real-time sensor measurements, control assets in the…

机器学习 · 计算机科学 2023-05-31 Abhiram Mullapudi , Branko Kerkez

This study presents a noise-robust closed-loop control strategy for wake flows employing model predictive control. The proposed control framework involves the autonomous offline selection of hyperparameters, eliminating the need for user…

流体动力学 · 物理学 2025-01-20 Luigi Marra , Andrea Meilán-Vila , Stefano Discetti

We present a data-driven nonlinear predictive control approach for the class of discrete-time multi-input multi-output feedback linearizable nonlinear systems. The scheme uses a non-parametric predictive model based only on input and noisy…

系统与控制 · 电气工程与系统科学 2023-03-28 Mohammad Alsalti , Victor G. Lopez , Julian Berberich , Frank Allgöwer , Matthias A. Müller

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Neural operators are promising surrogates for dynamical systems but when trained with standard L2 losses they tend to oversmooth fine-scale turbulent structures. Here, we show that combining operator learning with generative modeling…

流体动力学 · 物理学 2025-09-11 Vivek Oommen , Siavash Khodakarami , Aniruddha Bora , Zhicheng Wang , George Em Karniadakis

Neural-based, data-driven analysis and control of dynamical systems have been recently investigated and have shown great promise, e.g. for safety verification or stability analysis. Indeed, not only do neural networks allow for an entirely…

最优化与控制 · 数学 2023-12-14 Virginie Debauche , Alec Edwards , Raphael M. Jungers , Alessandro Abate

Nonlinear control techniques by means of a software sensor that are commonly used in chemical engineering could be also applied to genetic regulation processes. We provide here a realistic formulation of this procedure by introducing an…

生物物理 · 物理学 2009-11-10 V. Ibarra-Junquera , L. A. Torres , H. C. Rosu , G. Arguello , J. Collado-Vides

Based on a non-equilibrium mechanism for spatial pattern formation we study how position information can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of cells in a developing…

分子网络 · 定量生物学 2009-08-26 Thimo Rohlf , Stefan Bornholdt

By extracting unstable invariant solutions directly from body-forced three-dimensional turbulence, we study the dynamical processes at play when the forcing is large scale and either unidirectional in the momentum or the vorticity…

流体动力学 · 物理学 2017-04-26 Dan Lucas , Rich Kerswell