相关论文: An automated multiscale ensemble simulation approa…
In this paper, we are concerned with the simulation of blood flow in microvascular networks and the surrounding tissue. To reduce the computational complexity of this issue, the network structures are modeled by a one-dimensional graph,…
A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…
Currently, it is challenging to investigate aneurismal hemodynamics based on current in-vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we…
In the context of numerical simulations of the vascular system, local geometric uncertainties have not yet been examined in sufficient detail due to model complexity and the associated large numerical effort. Such uncertainties are related…
Most Computational Fluid Dynamics (CFD) studies of hemodynamics in intracranial aneurysms are based on the assumption of laminar flow due to a relatively low (below 500) parent artery Reynolds number. A few studies have recently…
Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based…
Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…
The heart is the central part of the cardiovascular network. Its role is to pump blood to various body organs. Many cardiovascular diseases occur due to an abnormal functioning of the heart. A diseased heart leads to severe complications…
The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…
In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…
Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…
Accurate segmentation of cerebral vasculature and a quantitative assessment of cerebrovascular morphology is critical to various diagnostic and therapeutic purposes and is pertinent to studying brain health and disease. However, this is…
A new two-dimensional model for blood flows in arteries with arbitrary cross sections is derived. The model consists of a system of balance laws for conservation of mass and balance of momentum in the axial and angular directions. The…
A deeper understanding of the influence of common cardiovascular diseases like stenosis, aneurysm or atherosclerosis on the circulatory mechanism is required, to establish new methods for early diagnosis. Different types of simulators were…
Many applications of computational fluid dynamics require multiple simulations of a flow under different input conditions. In this paper, a numerical algorithm is developed to efficiently determine a set of such simulations in which the…
Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…
Coronary artery disease (CAD) is one of the most common cardiac diseases worldwide and causes disability and economic burden. It is the world's leading and most serious cause of mortality, with approximately 80% of deaths reported in low-…
Multiple Sclerosis (MS) is a disorder that usually appears in adults in their thirties. It has a prevalence that ranges between 2 and 150 per 100 000. Epidemiological studies of MS have provided hints on possible causes for the disease…
Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its major treatable risk factor is the intra-ocular pressure, although other biomarkers are being explored to improve the understanding of the…