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Small groups of interneurons, abbreviated by CPG for central pattern generators, are arranged into neural networks to generate a variety of core bursting rhythms with specific phase-locked states, on distinct time scales, that govern vital…

混沌动力学 · 物理学 2015-06-17 Sajiya Jalil , Dane Allen , Joe Youker , Andrey Shilnikov

Living creatures exhibit a remarkable diversity of locomotion mechanisms, evolving structures specialised for interacting with their environment. In the vast majority of cases, locomotor behaviours such as flying, crawling, and running, are…

生物物理 · 物理学 2020-07-28 Kirsty Y. Wan

We propose a novel discrete model of central pattern generators (CPG), neuronal ensembles generating rhythmic activity. The model emphasizes the role of nonsynaptic interactions and the diversity of electrical properties in nervous systems.…

神经与进化计算 · 计算机科学 2017-05-10 Nikolay Bazenkov , Varvara Dyakonova , Oleg Kuznetsov , Dmitri Sakharov , Dmitry Vorontsov , Liudmila Zhilyakova

Legged locomotion is a challenging task in the field of robotics but a rather simple one in nature. This motivates the use of biological methodologies as solutions to this problem. Central pattern generators are neural networks that are…

神经与进化计算 · 计算机科学 2020-03-18 Elie Aljalbout , Florian Walter , Florian Röhrbein , Alois Knoll

The purpose of this paper is trifold -- to serve as an instructive resource and a reference catalog for biologically plausible modeling with i) conductance-based models, coupled with ii) strength-varying slow synapse models, culminating in…

神经元与认知 · 定量生物学 2022-11-02 James Scully , Jassem Bourahmah , David Bloom , Andrey L Shilnikov

Constructing electronic models of neurons has several applications including reproducing dynamics of biological neurons and their networks and neuroprosthetics. In the brain, most neurons themselves are in a non-oscillatory mode, and brain…

适应与自组织系统 · 物理学 2023-05-09 Nikita M. Egorov , Marina V. Sysoeva , Vladimir I. Ponomarenko , Ilya V. Sysoev

Neural circuits in the brain perform a variety of essential functions, including input classification, pattern completion, and the generation of rhythms and oscillations that support processes such as breathing and locomotion. There is also…

神经元与认知 · 定量生物学 2024-10-16 Juliana Londono Alvarez

We explore the dynamics of the preB\"{o}tzinger complex, the mammalian central pattern generator with $N \sim 10^3$ neurons, which produces a collective metronomic signal that times the inspiration. Our analysis is based on a simple…

神经元与认知 · 定量生物学 2020-07-01 Mihai Bibireata , Valentin M. Slepukhin , Alex J. Levine

We present a novel framework for central pattern generator design that leverages the intrinsic rebound excitability of neurons in combination with winner-takes-all computation. Our approach unifies decision-making and rhythmic pattern…

系统与控制 · 电气工程与系统科学 2025-04-16 Yongkang Huo , Fuvio Forni , Rodolphe Sepulchre

Bump attractors are wandering localised patterns observed in in vivo experiments of spatially-extended neurobiological networks. They are important for the brain's navigational system and specific memory tasks. A bump attractor is…

动力系统 · 数学 2021-12-15 D. Avitabile , J. L. Davis , K. C. A. Wedgwood

We analyze the dynamics of the neural circuit of the lamprey central pattern generator (CPG). This analysis provides insights into how neural interactions form oscillators and enable spontaneous oscillations in a network of damped…

神经元与认知 · 定量生物学 2009-11-10 Li Zhaoping , Alex Lewis , Silvia Scarpetta

Elucidating the neurophysiological mechanisms underlying neural pattern formation remains an outstanding challenge in Computational Neuroscience. In this paper, we address the issue of understanding the emergence of neural patterns by…

神经元与认知 · 定量生物学 2024-06-04 Gregory Dumont , Carmen Oana Tarniceriu

Oscillatory dynamics of complex networks has recently attracted great attention. In this paper we study pattern formation in oscillatory complex networks consisting of excitable nodes. We find that there exist a few center nodes and small…

混沌动力学 · 物理学 2011-11-23 Liao Xuhong , Xia Qinzhi , Qian Yu , Zhang Lisheng , Hu Gang , Mi Yuanyuan

Stick insect stepping patterns have been studied for insights about locomotor rhythm generation and control, because the underlying neural system is relatively accessible experimentally and produces a variety of rhythmic outputs. Harnessing…

神经元与认知 · 定量生物学 2025-04-17 Zahra Aminzare , Jonathan E. Rubin

Rhythm is a fundamental aspect of human behaviour, present from infancy and deeply embedded in cultural practices. Rhythm anticipation is a spontaneous cognitive process that typically occurs before the onset of actual beats. While most…

神经元与认知 · 定量生物学 2025-03-18 Zhongju Yuan , Geraint Wiggins , Dick Botteldooren

The Turing patterning mechanism is believed to underly the formation of repetitive structures in development, such as zebrafish stripes and mammalian digits, but it has proved difficult to isolate the specific biochemical species…

分子网络 · 定量生物学 2018-03-22 Stephen Smith , Neil Dalchau

Gamma-band rhythmic inhibition is a ubiquitous phenomenon in neural circuits yet its computational role still remains elusive. We show that a model of Gamma-band rhythmic inhibition allows networks of coupled cortical circuit motifs to…

神经元与认知 · 定量生物学 2017-11-08 Hesham Mostafa , Lorenz K. Muller , Giacomo Indiveri

Larval zebrafish exhibit a variety of complex undulatory swimming patterns. This repertoire is controlled by the 300 neurons projecting from brain into spinal cord. Understanding how descending control signals shape the output of spinal…

神经元与认知 · 定量生物学 2007-05-23 Scott A. Hill , Xiao-Ping Liu , Melissa A. Borla , Jorge V. Jose , Donald M. O'Malley

The enteric bacterium Proteus mirabilis, which is a pathogen that forms biofilms in vivo, can swarm over hard surfaces and form concentric ring patterns in colonies. Colony formation involves two distinct cell types: swarmer cells that…

种群与进化 · 定量生物学 2015-05-28 Chuan Xue , Elena O. Budrene , Hans G. Othmer

Central Pattern Generators (CPGs) models have been long used to investigate both the neural mechanisms that underlie animal locomotion as well as a tool for robotic research. In this work we propose a spiking CPG neural network and its…

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