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Determining functional brain connectivity is crucial to understanding the brain and neural differences underlying disorders such as autism. Recent studies have used Gaussian graphical models to learn brain connectivity via statistical…

神经元与认知 · 定量生物学 2017-09-22 Chandan Singh , Beilun Wang , Yanjun Qi

Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from alterations in patients without FBTCS. Methods: We…

Emerging evidence shows that the modular organization of the human brain allows for better and efficient cognitive performance. Many of these cognitive functions are very fast and occur in subsecond time scale such as the visual object…

神经元与认知 · 定量生物学 2018-08-01 J. Rizkallah , P. Benquet , A. Kabbara , O. Dufor , F. Wendling , M. Hassan

Autism Spectrum Disorder (ASD) is a multi-factorial neurodevelopmental disorder, whose causes are still poorly understood. Effective therapies to reduce all the heterogeneous symptoms of the disorder do not exists yet, but behavioural…

神经元与认知 · 定量生物学 2025-06-02 Elisa Ferrari , Alessandra Retico , Alessandro Cellerino , Davide Bacciu

Dementia poses a growing challenge in our aging society. Frontotemporal dementia (FTD) and Alzheimer disease (AD) are the leading causes of early-onset dementia. FTD and AD display unique traits in their onset, progression, and treatment…

信号处理 · 电气工程与系统科学 2024-09-26 Shivani Ranjan , Lalan Kumar

[See full abstract in the pdf] Formal Thought Disorder (FTD), which is a group of symptoms in cognition that affects language and thought, can be observed through language. FTD is seen across such developmental or psychiatric disorders as…

计算与语言 · 计算机科学 2023-10-17 Takeshi Saga , Hiroki Tanaka , Satoshi Nakamura

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

神经元与认知 · 定量生物学 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) are neurodevelopmental conditions which impact on a significant number of children and adults. Currently, the diagnosis of such disorders is done by experts…

计算机视觉与模式识别 · 计算机科学 2016-12-08 Shashank Jaiswal , Michel Valstar , Alinda Gillott , David Daley

Investigations of the human connectome have elucidated core features of adult structural networks, particularly the crucial role of hub-regions. However, little is known regarding network organisation of the healthy elderly connectome, a…

神经元与认知 · 定量生物学 2015-12-15 Alistair Perry , Wei Wen , Anton Lord , Anbupalam Thalamuthu , Perminder Sachdev , Michael Breakspear

Since the strong comorbid similarity in NDDs, such as attention-deficit hyperactivity disorder, can interfere with the accurate diagnosis of autism spectrum disorder (ASD), identifying unknown classes is extremely crucial and challenging…

计算机视觉与模式识别 · 计算机科学 2024-10-28 Jiaming Yu , Zihao Guan , Xinyue Chang , Shujie Liu , Zhenshan Shi , Xiumei Liu , Changcai Yang , Riqing Chen , Lanyan Xue , Lifang Wei

Recent applications of pattern recognition techniques on brain connectome classification using functional connectivity (FC) are shifting towards acknowledging the non-Euclidean topology and dynamic aspects of brain connectivity across time.…

机器学习 · 计算机科学 2024-11-12 Sin-Yee Yap , Junn Yong Loo , Chee-Ming Ting , Fuad Noman , Raphael C. -W. Phan , Adeel Razi , David L. Dowe

The brain's attention system is a complex and adaptive network of brain regions that enables individuals to interact effectively with their surroundings and perform complex tasks. This system involves the coordination of various brain…

人机交互 · 计算机科学 2024-05-03 Shiva Ghasemi , Majid Behravan , Sunday Uber , Denis Gracanin

When the human brain manifests the birth of organised communication among local and large-scale neuronal populations activity remains undescribed. We report, in resting-state EEG source-estimates of 100 infants at term age, the existence of…

神经元与认知 · 定量生物学 2020-09-08 Steve Mehrkanoon

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

Theories for autism spectrum disorder (ASD) have been formulated at different levels: ranging from physiological observations to perceptual and behavioral descriptions. Understanding the physiological underpinnings of perceptual traits in…

神经元与认知 · 定量生物学 2021-12-03 Rodrigo Echeveste , Enzo Ferrante , Diego H. Milone , Inés Samengo

Anatomical connectivity between different regions in the brain can be mapped to a network representation, the connectome, where the intensities of the links, the weights, influence its structural resilience and the functional processes it…

神经元与认知 · 定量生物学 2025-04-09 Laia Barjuan , Muhua Zheng , M. Ángeles Serrano

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and behavioral patterns. Eye movement data offers a non-invasive diagnostic tool for ASD detection, as it is inherently…

机器学习 · 计算机科学 2026-01-12 Zhanpei Huang , Taochen chen , Fangqing Gu , Yiqun Zhang

The human brain dynamically integrated and configured information to adapt to the environment. To capture these changes over time, dynamic second-order functional connectivity was typically used to capture transient brain patterns. However,…

神经元与认知 · 定量生物学 2025-07-01 Qiang Li , Vince D. Calhoun , Armin Iraji

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

统计方法学 · 统计学 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

The increasing prevalence of Autism Spectrum Disorder and Attention-Deficit/ Hyperactivity Disorder among students highlights the need to improve evaluation and diagnostic techniques, as well as effective tools to mitigate the negative…

计算机视觉与模式识别 · 计算机科学 2024-01-31 S. Fortea-Sevilla , A. Garcia-Sosa. , P. Morales-Almeida , C. Carmona-Duarte