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We have analyzed the effects of the addition of external noise to non-dynamical systems displaying intrinsic noise, and established general conditions under which stochastic resonance appears. The criterion we have found may be applied to a…

凝聚态物理 · 物理学 2016-08-15 J. M. G. Vilar , G. Gomila , J. M. Rubí

We investigate the effect of noisy feed rates on the behavior of a cubic autocatalytic chemical reaction model. By combining the renormalization group and stoichiometric network analysis, we demonstrate how externally adjustable random…

统计力学 · 物理学 2018-12-21 Jean-Sebastien Gagnon , David Hochberg , Juan Perez-Mercader

Cell decision-making refers to the process by which cells gather information from their local microenvironment and regulate their internal states to create appropriate responses. Microenvironmental cell sensing plays a key role in this…

生物物理 · 物理学 2023-04-19 Arnab Barua , Haralampos Hatzikirou

We investigate the lifetime of dynamical regimes under the impact of noise motivated by low-dimensional models of the atmosphere. One may expect that the inclusion of noise tends to make the system leave prescribed regions of the state…

数值分析 · 数学 2026-05-01 Henry Schoeller , Robin Chemnitz , Péter Koltai , Maximilian Engel , Stephan Pfahl

In high-dimensional data, structured noise caused by observed and unobserved factors affecting multiple target variables simultaneously, imposes a serious challenge for modeling, by masking the often weak signal. Therefore, (1) explaining…

A method is provided for approximating random slow manifolds of a class of slow-fast stochastic dynamical systems. Thus approximate, low dimensional, reduced slow systems are obtained analytically in the case of sufficiently large time…

动力系统 · 数学 2013-03-12 Jian Ren , Jinqiao Duan , Christopher K. R. T. Jones

Noise is an inherent part of neuronal dynamics, and thus of the brain. It can be observed in neuronal activity at different spatiotemporal scales, including in neuronal membrane potentials, local field potentials, electroencephalography,…

神经元与认知 · 定量生物学 2019-01-03 Daqing Guo , Matjaz Perc , Tiejun Liu , Dezhong Yao

Intrinsic transcriptional noise induced by operator fluctuations is investigated with a simple spin like stochastic model. The effects of transcriptional fluctuations in protein synthesis is probed by coupling transcription and translation…

其他定量生物学 · 定量生物学 2007-05-23 Guilherme da C. P. Innocentini , Jose E. M. Hornos

We present a novel approach allowing the study of rare events like fixation under fluctuating environments, modeled as extrinsic noise, in evolutionary processes characterized by the dominance of one species. Our treatment consists of…

种群与进化 · 定量生物学 2013-12-16 Michael Assaf , Mauro Mobilia , Elijah Roberts

Stochastic resetting and noise-enhanced stability are two phenomena which can affect the lifetime and relaxation of nonequilibrium states. They can be considered as measures of controlling the efficiency of the completion process when a…

统计力学 · 物理学 2022-06-22 Karol Capała , Bartłomiej Dybiec , Ewa Gudowska-Nowak

The intrinsic stochasticity of gene expression can lead to large variability of protein levels across a population of cells. Variability (or noise) in protein distributions can be modulated by cellular mechanisms of gene regulation; in…

分子网络 · 定量生物学 2011-03-02 Tao Jia , Rahul V. Kulkarni

Molecular noise in gene regulatory networks has two intrinsic components, one part being due to fluctuations caused by the birth and death of protein or mRNA molecules which are often present in small numbers and the other part arising from…

分子网络 · 定量生物学 2015-11-17 Davit A. Potoyan , Peter G. Wolynes

The paradigm of stochastic resonance (SR)---the idea that signal detection and transmission may benefit from noise---has met with great interest in both physics and the neurosciences. We investigate here the consequences of reducing the…

生物物理 · 物理学 2009-11-06 Hans E. Plesser , Theo Geisel

In this paper we present a general framework in which one can rigorously study the effect of spatio-temporal noise on traveling waves, stationary patterns and oscillations that are invariant under the action of a finite-dimensional set of…

动力系统 · 数学 2020-06-24 James MacLaurin

We show how one may analytically compute the stationary density of the distribution of molecular constituents in populations of cells in the presence of noise arising from either bursting transcription or translation, or noise in…

分子网络 · 定量生物学 2015-10-15 Michael C. Mackey , Marta Tyran-Kamińska , Romain Yvinec

Noise appears in the brain due to various sources, such as ionic channel fluctuations and synaptic events. They affect the activities of the brain and influence neuron action potentials. Stochastic differential equations have been used to…

A comparative stochastic and deterministic study of a family of SEIRS epidemic dynamic models for malaria is presented. The family type is determined by the qualitative behavior of the nonlinear incidence rates of the disease. Furthermore,…

种群与进化 · 定量生物学 2018-09-12 Divine Wanduku

While noise is generally associated with uncertainties and often has a negative connotation in engineering, living organisms have evolved to adapt to (and even exploit) such uncertainty to ensure the survival of a species or implement…

分子网络 · 定量生物学 2022-09-29 Corentin Briat , Mustafa Khammash

The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule…

生物物理 · 物理学 2014-06-12 Jay Newby

Unidirectionally coupled dynamical system is studied by focusing on the input (or boundary) dependence. Due to convective instability, noise at an up-flow is spatially amplified to form an oscillation. The response, given by the down-flow…

chao-dyn · 物理学 2009-10-31 Koichi Fujimoto , Kunihiko Kaneko