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An important step for any causal inference study design is understanding the distribution of the treated and control subjects in terms of measured baseline covariates. However, not all baseline variation is equally important. In the…

统计方法学 · 统计学 2021-07-02 Rachael C. Aikens , Michael Baiocchi

Pattern extraction algorithms are enabling insights into the ever-growing amount of today's datasets by translating reoccurring data properties into compact representations. Yet, a practical problem arises: With increasing data volumes and…

信息检索 · 计算机科学 2018-07-05 Michael Behrisch , Robert Krueger , Fritz Lekschas , Tobias Schreck , Nils Gehlenborg , Hanspeter Pfister

Treatment recommendations within Clinical Practice Guidelines (CPGs) are largely based on findings from clinical trials and case studies, referred to here as research studies, that are often based on highly selective clinical populations,…

Using causal relations to guide decision making has become an essential analytical task across various domains, from marketing and medicine to education and social science. While powerful statistical models have been developed for inferring…

人机交互 · 计算机科学 2020-09-08 Xiao Xie , Fan Du , Yingcai Wu

Carotid artery plaques can cause arterial vascular diseases such as stroke and myocardial infarction, posing a severe threat to human life. However, the current clinical examination mainly relies on a direct assessment by physicians of…

人机交互 · 计算机科学 2023-08-15 Chaoqing Xu , Zhentao Zheng , Yiting Fu , Baofeng Chang , Legao Chen , Minghui Wu , Mingli Song , Jinsong Jiang

Real world observational data, together with causal inference, allow the estimation of causal effects when randomized controlled trials are not available. To be accepted into practice, such predictive models must be validated for the…

Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with…

医学物理 · 物理学 2020-03-25 Rongchen Guo , Takanori Fujiwara , Yiran Li , Kelly M. Lima , Soman Sen , Nam K. Tran , Kwan-Liu Ma

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Analysts often make visual causal inferences about possible data-generating models. However, visual analytics (VA) software tends to leave these models implicit in the mind of the analyst, which casts doubt on the statistical validity of…

人机交互 · 计算机科学 2021-07-29 Alex Kale , Yifan Wu , Jessica Hullman

In healthcare prediction tasks, it is essential to exploit the correlations between medical features and learn better patient health representations. Existing methods try to estimate feature correlations only from data, or increase the…

机器学习 · 计算机科学 2022-05-24 Xinyu Ma , Xu Chu , Yasha Wang , Hailong Yu , Liantao Ma , Wen Tang , Junfeng Zhao

Understanding the spread of any disease is a highly complex and interdisciplinary exercise as biological, social, geographic, economic, and medical factors may shape the way a disease moves through a population and options for its eventual…

种群与进化 · 定量生物学 2016-12-14 Aristides Moustakas

Modern epidemiology integrates knowledge from heterogeneous collections of data consisting of numerical, descriptive and imaging. Large-scale epidemiological studies use sophisticated statistical analysis, mathematical models using…

定量方法 · 定量生物学 2012-10-11 Arash Sangari , Adel Ardalan , Larry Lambe , Hamid Eghbalnia , Amir H. Assadi

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

种群与进化 · 定量生物学 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

Recent advances in types and extent of medical imaging technologies has led to proliferation of multimodal quantitative imaging data in cancer. Quantitative medical imaging data refer to numerical representations derived from medical…

Spatially-resolved omics-data enable researchers to precisely distinguish cell types in tissue and explore their spatial interactions, enabling deep understanding of tissue functionality. To understand what causes or deteriorates a disease…

Rapid advances in image processing capabilities have been seen across many domains, fostered by the application of machine learning algorithms to "big-data". However, within the realm of medical image analysis, advances have been curtailed,…

Visual statistical inference is a way to determine significance of patterns found while exploring data. It is dependent on the evaluation of a lineup, of a data plot among a sample of null plots, by human observers. Each individual is…

应用统计 · 统计学 2014-08-12 Mahbubul Majumder , Heike Hofmann , Dianne Cook

Background: Citation analysis has become an important tool for research performance assessment in the medical sciences. However, different areas of medical research may have considerably different citation practices, even within the same…

数字图书馆 · 计算机科学 2015-06-11 Nees Jan van Eck , Ludo Waltman , Anthony F. J. van Raan , Robert J. M. Klautz , Wilco C. Peul

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of…

图像与视频处理 · 电气工程与系统科学 2020-11-12 Naira Elazab , Hassan Soliman , Shaker El-Sappagh , S. M. Riazul Islam , Mohammed Elmogy

Set classification problems arise when classification tasks are based on sets of observations as opposed to individual observations. In set classification, a classification rule is trained with $N$ sets of observations, where each set is…

统计方法学 · 统计学 2016-03-08 Sungkyu Jung , Xingye Qiao