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Small sample sizes in clinical studies arises from factors such as reduced costs, limited subject availability, and the rarity of studied conditions. This creates challenges for accurately calculating confidence intervals (CIs) using the…

统计方法学 · 统计学 2025-11-11 Mulan Wu , Mengyu Xu , Dongyun Kim

In this paper, we discuss causal inference on the efficacy of a treatment or medication on a time-to-event outcome with competing risks. Although the treatment group can be randomized, there can be confoundings between the compliance and…

统计方法学 · 统计学 2016-12-06 Cheng Zheng , Ran Dai , Parameswaran Hari , Mei-Jie Zhang

When constructing a model to estimate the causal effect of a treatment, it is necessary to control for other factors which may have confounding effects. Because the ignorability assumption is not testable, however, it is usually unclear…

统计方法学 · 统计学 2022-09-07 Spencer Woody , Carlos M. Carvalho , Jared S. Murray

This paper tackles a fundamental inference problem: given $n$ observations from a distribution $P$ over $\mathbb{R}^d$ with unknown mean $\boldsymbol{\mu}$, we must form a confidence set for the index (or indices) corresponding to the…

统计理论 · 数学 2025-09-23 Ilmun Kim , Aaditya Ramdas

Selecting between competing statistical models is a challenging problem especially when the competing models are non-nested. In this paper we offer a simple solution by devising an algorithm which combines MCMC and importance sampling to…

Recently the renormalization group predictions on the effect of disorder on pinning models have been put on mathematical grounds. The picture is particularly complete if the disorder is 'relevant' or 'irrelevant' in the Harris criterion…

数学物理 · 物理学 2009-06-11 Giambattista Giacomin , Hubert Lacoin , Fabio Lucio Toninelli

This paper examines the biases and performance of several uncertain inference systems: Mycin, a variant of Mycin. and a simplified version of probability using conditional independence assumptions. We present axiomatic arguments for using…

人工智能 · 计算机科学 2013-04-12 Ben P. Wise

Recently, several researchers have claimed that conclusions obtained from a Bayes factor (or the posterior odds) may contradict those obtained from Bayesian posterior estimation. In this short paper, we wish to point out that no such…

统计理论 · 数学 2022-10-24 Harlan Campbell , Paul Gustafson

Unmeasured confounding is a key threat to reliable causal inference based on observational studies. Motivated from two powerful natural experiment devices, the instrumental variables and difference-in-differences, we propose a new method…

统计方法学 · 统计学 2021-11-09 Ting Ye , Ashkan Ertefaie , James Flory , Sean Hennessy , Dylan S. Small

Some units from a population receive the same treatment that is different from treatments available for other reservoir populations. The minimal sufficient statistic $s$ for the pre-treatment $x$-covariates's distributions in the…

统计理论 · 数学 2014-08-05 Yannis G. Yatracos

Causal inference from observational data requires assumptions. These assumptions range from measuring confounders to identifying instruments. Traditionally, causal inference assumptions have focused on estimation of effects for a single…

机器学习 · 统计学 2019-03-04 Rajesh Ranganath , Adler Perotte

In this work, we consider causal inference in various high-dimensional treatment settings, including for single multi-valued treatments and vector treatments with binary or continuous components, when the number of treatments can be…

统计理论 · 数学 2026-02-26 Patrick Kramer , Edward H. Kennedy , Isaac M. Opper

We provide a simple distribution regression estimator for treatment effects in the difference-in-differences (DiD) design. Our procedure is particularly useful when the treatment effect differs across the distribution of the outcome…

计量经济学 · 经济学 2026-05-20 Iván Fernández-Val , Jonas Meier , Aico van Vuuren , Francis Vella

In mathematical finance, Levy processes are widely used for their ability to model both continuous variation and abrupt, discontinuous jumps. These jumps are practically relevant, so reliable inference on the feature that controls jump…

统计理论 · 数学 2021-09-21 Zhe Wang , Ryan Martin

The Minimum Covariance Determinant (MCD) method is a highly robust estimator of multivariate location and scatter, for which a fast algorithm is available. Since estimating the covariance matrix is the cornerstone of many multivariate…

统计方法学 · 统计学 2021-01-13 Mia Hubert , Michiel Debruyne , Peter J. Rousseeuw

Recent advances in Markov chain Monte Carlo (MCMC) extend the scope of Bayesian inference to models for which the likelihood function is intractable. Although these developments allow us to estimate model parameters, other basic problems…

统计计算 · 统计学 2019-12-12 Minh-Ngoc Tran , Marcel Scharth , David Gunawan , Robert Kohn , Scott D. Brown , Guy E. Hawkins

We examine a probabilistic model for the diagnosis of multiple diseases. In the model, diseases and findings are represented as binary variables. Also, diseases are marginally independent, features are conditionally independent given…

人工智能 · 计算机科学 2022-12-07 David Heckerman

Missing data are often dealt with multiple imputation. A crucial part of the multiple imputation process is selecting sensible models to generate plausible values for incomplete data. A method based on posterior predictive checking is…

统计计算 · 统计学 2026-05-14 Mingyang Cai , Stef van Buuren , Gerko Vink

Gibbs sampling methods are standard tools to perform posterior inference for mixture models. These have been broadly classified into two categories: marginal and conditional methods. While conditional samplers are more widely applicable…

统计方法学 · 统计学 2023-02-21 Pierpaolo De Blasi , María F. Gil-Leyva

Background: Although the missing covariate indicator method (MCIM) has been shown to be biased under extreme conditions, the degree and determinants of bias have not been formally assessed. We derived the formula for the relative bias in…

应用统计 · 统计学 2025-08-01 Gang Xu , Mingyang Song , Xin Zhou , Yilun Wu , Mathew Pazaris , Donna Spiegelman