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A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

种群与进化 · 定量生物学 2017-09-05 Kristoffer Spricer , Pieter Trapman

Human pathogens transmitted through environmental pathways are subject to stress and pressures outside of the host. These pressures may cause pathogen pathovars to diverge in their environmental persistence and their infectivity on an…

种群与进化 · 定量生物学 2018-02-16 Andrew F. Brouwer , Marisa C. Eisenberg , Nancy G. Love , Joseph N. S. Eisenberg

Infectious disease outbreaks have precipitated a profusion of mathematical models. Epidemic curves predicted by these models are typically qualitatively similar, despite distinct model assumptions, but there is no theoretical explanation…

种群与进化 · 定量生物学 2026-02-23 David J. D. Earn , Todd L. Parsons

A key scientific challenge during the outbreak of novel infectious diseases is to predict how the course of the epidemic changes under different countermeasures that limit interaction in the population. Most epidemiological models do not…

The time variation of contacts in a networked system may fundamentally alter the properties of spreading processes and affect the condition for large-scale propagation, as encoded in the epidemic threshold. Despite the great interest in the…

物理与社会 · 物理学 2015-04-14 Eugenio Valdano , Luca Ferreri , Chiara Poletto , Vittoria Colizza

The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…

种群与进化 · 定量生物学 2020-04-15 Laurent Hébert-Dufresne , Benjamin M. Althouse , Samuel V. Scarpino , Antoine Allard

The study of epidemic spreading on populations of networked individuals has seen recently a great deal of significant progresses. A common point of all past studies is, however, that there is only one peak of infected density in each single…

物理与社会 · 物理学 2018-05-09 Muhua Zheng , Wei Wang , Ming Tang , Jie Zhou , S. Boccaletti , Zonghua Liu

The mathematical model of the spread of the epidemic is developed, which considers fluctuations in the number of human social contacts. The model is based on the logistic equation. The oscillation in the number of social contacts within one…

物理与社会 · 物理学 2021-06-01 S. P. Fisenko , P. S. Grinchuk

In the study of infectious diseases on networks, researchers calculate epidemic thresholds to help forecast whether a disease will eventually infect a large fraction of a population. Because network structure typically changes in time,…

社会与信息网络 · 计算机科学 2021-08-11 Qinyi Chen , Mason A. Porter

The dynamical evolution of many economic, sociological, biological and physical systems tends to be dominated by a relatively small number of unexpected, large changes (`extreme events'). We study the large, internal changes produced in a…

无序系统与神经网络 · 物理学 2009-11-07 D. Lamper , S. Howison , N. F. Johnson

Forecasting disease spread is a critical tool to help public health officials design and plan public health interventions. However, the expected future state of an epidemic is not necessarily well defined as disease spread is inherently…

种群与进化 · 定量生物学 2026-05-05 Mariah C. Boudreau , Andrea J. Allen , Nicholas J. Roberts , Antoine Allard , Laurent Hébert-Dufresne

We study the problem of estimating the origin of an epidemic outbreak -- given a contact network and a snapshot of epidemic spread at a certain time, determine the infection source. Finding the source is important in different contexts of…

物理与社会 · 物理学 2014-11-20 Andrey Y. Lokhov , Marc Mézard , Hiroki Ohta , Lenka Zdeborová

Although there is always an interplay between the dynamics of information diffusion and disease spreading, the empirical research on the systemic coevolution mechanisms connecting these two spreading dynamics is still lacking. Here we…

物理与社会 · 物理学 2016-07-07 Wei Wang , Quan-Hui Liu , Shi-Min Cai , Ming Tang , Lidia A. Braunstein , H. Eugene Stanley

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

种群与进化 · 定量生物学 2010-11-25 Christel Kamp

Upon an outbreak of a dangerous infectious disease, people generally tend to reduce their contacts with others in fear of getting infected. Such typical actions apparently help slow down the spreading of infection. Thanks to today's broad…

物理与社会 · 物理学 2011-12-26 Yubo Wang , Gaoxi Xiao , Limsoon Wong , Xiuju Fu , Stefan Ma , Tee Hiang Cheng

Weak ties play a significant role in the structures and the dynamics of community networks. Based on the susceptible-infected model in contact process, we study numerically how weak ties influence the predictability of epidemic dynamics. We…

物理与社会 · 物理学 2012-07-05 Panpan Shu , Ming Tang , Kai Gong , Ying Liu

Nowadays, one of the challenges we face when carrying out modeling of epidemic spreading is to develop methods to control disease transmission. In this article we study how the spreading of knowledge of a disease affects the propagation of…

Contacts between individuals serve as pathways where infections may propagate. These contact patterns can be represented by network structures. Static structures have been the common modeling paradigm but recent results suggest that…

种群与进化 · 定量生物学 2012-04-25 Luis Enrique Correa Rocha , Adeline Decuyper , Vincent D Blondel

The dynamics of epidemic spreading is often reduced to the single control parameter $R_0$, whose value, above or below unity, determines the state of the contagion. If, however, the pathogen evolves as it spreads, $R_0$ may change over…

种群与进化 · 定量生物学 2022-11-07 Xiyun Zhang , Zhongyuan Ruan , Muhua Zheng , Jie Zhou , Stefano Boccaletti , Baruch Barzel

Despite the advanced stage of epidemic modeling, there is a major demand for methods to incorporate behavioral responses to the spread of a disease such as social distancing and adoption of prevention methods. Mobility plays an important…

物理与社会 · 物理学 2022-03-14 Paulo Cesar Ventura , Alberto Aleta , Francisco A. Rodrigues , Yamir Moreno