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Detection limit (DL) has become an increasingly ubiquitous issue in statistical analyses of biomedical studies, such as cytokine, metabolite and protein analysis. In regression analysis, if an explanatory variable is left-censored due to…

Detection limits are common in biomedical and environmental studies, where key covariates or outcomes are censored below an assay-specific threshold. Standard approaches such as complete-case analysis, single-value substitution, and…

统计方法学 · 统计学 2025-12-12 Y. Xu , S. Tu L. Shao , T. Lin , X. M. Tu

We consider linear regression model estimation where the covariate of interest is randomly censored. Under a non-informative censoring mechanism, one may obtain valid estimates by deleting censored observations. However, this comes at a…

应用统计 · 统计学 2017-10-24 Folefac Atem , Roland A. Matsouaka

Interval censoring arises frequently in clinical, epidemiological, financial, and sociological studies, where the event or failure of interest is known only to occur within an interval induced by periodic monitoring. We formulate the…

统计方法学 · 统计学 2016-03-01 Donglin Zeng , Lu Mao , D. Y. Lin

Missing covariates are not uncommon in capture-recapture studies. When covariate information is missing at random in capture-recapture data, an empirical full likelihood method has been demonstrated to outperform…

统计方法学 · 统计学 2025-07-15 Yang Liu , Yukun Liu , Pengfei Li , Riquan Zhang

Cohort studies of the onset of a disease often encounter left-truncation on the event time of interest in addition to right-censoring due to variable enrollment times of study participants. Analysis of such event time data can be biased if…

统计方法学 · 统计学 2025-04-11 Spencer Matthews , Bin Nan

Regression method has been widely used to explore relationship between dependent and independent variables. In practice, data issues such as censoring and missing data often exist. When the response variable is (fixed) censored, Tobit…

统计方法学 · 统计学 2021-07-06 Hailin Huang

The paper deals with generalized functional regression. The aim is to estimate the influence of covariates on observations, drawn from an exponential distribution. The link considered has a semiparametric expression: if we are interested in…

统计理论 · 数学 2013-09-20 Irène Gannaz

We propose a novel estimation approach for a general class of semi-parametric time series models where the conditional expectation is modeled through a parametric function. The proposed class of estimators is based on a Gaussian…

统计方法学 · 统计学 2025-07-21 Mirko Armillotta , Paolo Gorgi

We propose new parametric frameworks of regression analysis with the conditional mode of a bounded response as the focal point of interest. Covariate effects estimation and prediction based on the maximum likelihood method under two new…

统计方法学 · 统计学 2020-06-22 Haiming Zhou , Xianzheng Huang

During the past few decades, missing-data problems have been studied extensively, with a focus on the ignorable missing case, where the missing probability depends only on observable quantities. By contrast, research into non-ignorable…

统计方法学 · 统计学 2019-08-06 Yukun Liu , Pengfei Li , Jing Qin

The cause of failure in cohort studies that involve competing risks is frequently incompletely observed. To address this, several methods have been proposed for the semiparametric proportional cause-specific hazards model under a missing at…

统计方法学 · 统计学 2020-02-24 Giorgos Bakoyannis , Ying Zhang , Constantin T. Yiannoutsos

Model averaging has demonstrated superior performance for ensemble forecasting in high-dimensional framework, its extension to incomplete datasets remains a critical but underexplored challenge. Moreover, identifying the parsimonious model…

统计方法学 · 统计学 2025-09-03 Wei Xiong , Dianliang Deng , Dehui Wang

In many public health problems, an important goal is to identify the effect of some treatment/intervention on the risk of failure for the whole population. A marginal proportional hazards regression model is often used to analyze such an…

统计理论 · 数学 2007-06-13 Donglin Zeng

Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional…

统计理论 · 数学 2018-10-05 Francis K. C. Hui , Chong You , Han Lin Shang , Samuel Müller

Interval-censored multi-state data arise in many studies of chronic diseases, where the health status of a subject can be characterized by a finite number of disease states and the transition between any two states is only known to occur…

统计方法学 · 统计学 2022-09-19 Yu Gu , Donglin Zeng , Gerardo Heiss , D. Y. Lin

When facing multivariate covariates, general semiparametric regression techniques come at hand to propose flexible models that are unexposed to the curse of dimensionality. In this work a semiparametric copula-based estimator for…

统计方法学 · 统计学 2016-03-25 Mickael De Backer , Anouar El Ghouch , Ingrid Van Keilegom

In this paper, we propose a new semiparametric regression estimator by using a hybrid technique of a parametric approach and a nonparametric penalized spline method. The overall shape of the true regression function is captured by the…

统计理论 · 数学 2012-02-17 Takuma Yoshida , Kanta Naito

We consider a class of semiparametric regression models which are one-parameter extensions of the Cox [J. Roy. Statist. Soc. Ser. B 34 (1972) 187-220] model for right-censored univariate failure times. These models assume that the hazard…

统计理论 · 数学 2007-06-13 Michael R. Kosorok , Bee Leng Lee , Jason P. Fine

This paper considers the problem of semi-parametric proportional hazards model fitting for interval, left and right censored survival times. We adopt a more versatile penalized likelihood method to estimate the baseline hazard and the…

统计方法学 · 统计学 2019-04-16 Jun Ma , Dominique-Laurent Couturier , Stephane Heritier , Ian Marschner
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