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This study presents a collection of physical devices and software services that fully automate Raman spectra measurements for liquid samples within a robotic facility. This method is applicable to various fields, with demonstrated efficacy…

Urea and creatinine are two important diagnostic components of urine. The study of creatinine in liquid phase is difficult due to its feeble concentration in urine. To bring down the detection limit, Raman spectroscopy of dried urine…

医学物理 · 物理学 2014-12-24 S. Kumar , S. K. Majumdar

Raman spectroscopy is a promising technique used for noninvasive analysis of samples in various fields of application due to its ability for fingerprint probing of samples at the molecular level. Chemometrics methods are widely used…

定量方法 · 定量生物学 2022-10-20 Yulia Khristoforova , Lyudmila Bratchenko , Ivan Bratchenko

Raman spectroscopy is a widely used, powerful, and nondestructive tool for studying the vibrational properties of bulk and low-dimensional materials. Raman spectra can be simulated using first-principles methods, but due to the high…

材料科学 · 物理学 2019-03-06 Arsalan Hashemi , Arkady V. Krasheninnikov , Martti Puska , Hannu-Pekka Komsa

In chemical processing and bioprocessing, conventional online sensors are limited to measure only basic process variables like pressure and temperature, pH, dissolved O and CO$_2$ and viable cell density (VCD). The concentration of other…

定量方法 · 定量生物学 2020-05-07 Semion Rozov

Raman spectroscopy is an important tool in the study of vibrational properties and composition of molecules, peptides and even proteins. Raman spectra can be simulated based on the change of the electronic polarizability with vibrations,…

计算物理 · 物理学 2024-04-30 Ethan Berger , Juha Niemelä , Outi Lampela , André H. Juffer , Hannu-Pekka Komsa

We introduce a scheme based on machine learning and deep neural networks to model the environmental dependence of the electronic polarizability in insulating materials. Application to liquid water shows that training the network with a…

化学物理 · 物理学 2020-06-24 Grace M. Sommers , Marcos F. Calegari Andrade , Linfeng Zhang , Han Wang , Roberto Car

Raman spectroscopy's capability to provide meaningful composition predictions is heavily reliant on a pre-processing step to remove insignificant spectral variation. This is crucial in biofluid analysis. Widespread adoption of diagnostics…

信号处理 · 电气工程与系统科学 2019-04-05 Emily E Storey , Amr S. Helmy

Accurate detection and analysis of traces of persistent organic pollutants in water is important in many areas, including environmental monitoring and food quality control, due to their long environmental stability and potential…

机器学习 · 计算机科学 2024-02-02 Vishnu Jayaprakash , Jae Bem You , Chiranjeevi Kanike , Jinfeng Liu , Christopher McCallum , Xuehua Zhang

Raman spectroscopy is a label-free, chemically specific optical technique which provides detailed information about the chemical composition and structure of the excited analyte. Because of this, there is growing research interest in…

A machine learning method for prediction of Raman gain and noise spectra is presented: it guarantees high-accuracy (RMSE < 0.4 dB) and low computational complexity making it suitable for real-time implementation in future optical networks…

信号处理 · 电气工程与系统科学 2019-05-03 Ann Margareth Rosa Brusin , Vittorio Curri , Darko Zibar , Andrea Carena

Raman spectroscopy is widely applied to detect different chemical compounds in organic matter and create label-free high-resolution maps on the level of separate cells. The main advantage of this technique is the possibility to study…

应用物理 · 物理学 2025-01-15 Petr Shvets , Aleksandr Goikhman

Strain engineering in semiconductor transistor devices has become vital in the semiconductor industry due to the ever increasing need for performance enhancement at the nanoscale. Raman spectroscopy is a non-invasive measurement technique…

光学 · 物理学 2021-06-17 V. Prabhakara , T. Nuytten , H. Bender , W. Vandervorst , S. Bals , J. Verbeeck

We demonstrate low-frequency interferometric impulsive stimulated Raman scattering (ISRS) imaging with high robustness to distortions by optical scattering. ISRS is a pump-probe coherent Raman spectroscopy that can capture Raman vibrational…

We demonstrate a method to double the collection efficiency in Laser Tweezers Raman Spectroscopy (LTRS) by collecting both the forward and back-scattered light in a single-shot multitrack measurement. Our method can collect signals at…

光学 · 物理学 2021-06-09 Tobias Dahlberg , Magnus Andersson

Raman spectroscopy has attracted interest as a non-invasive optical technique to study the composition and structure of a wide range of materials at the microscopic level. The intrinsic fluorescence background can be orders of magnitude…

材料科学 · 物理学 2015-10-28 P. J. Cadusch , M. M. Hlaing , S. A. Wade , S. L. McArthur , P. R. Stoddart

We revisit laser intensity noise in the context of stimulated Raman scattering (SRS), which has recently proved to be a key technique to provide label free images of chemical bonds in biological and medical samples. Contrary to most…

仪器与探测器 · 物理学 2019-10-29 Xavier Audier , Sandro Heuke , Peter Volz , Ingo Rimke , Hervé Rigneault

In general, most of the substances in nature exist in mixtures, and the noninvasive identification of mixture composition with high speed and accuracy remains a difficult task. However, the development of Raman spectroscopy, machine…

信号处理 · 电气工程与系统科学 2022-02-02 Liangrui Pan , Peng Zhang , Chalongrat Daengngam , Mitchai Chongcheawchamnan

We introduce the first method to enable an optical amplification of a coherent Raman spectroscopy signal called radio frequency Doppler Raman spectroscopy. Doppler Raman measurements amplify the optical signals in coherent Raman…

An emerging application of Raman spectroscopy is monitoring the state of chemical reactors during biologic drug production. Raman shift intensities scale linearly with the concentrations of chemical species and thus can be used to…

信号处理 · 电气工程与系统科学 2023-06-30 Dexter Antonio , Hannah O'Toole , Randy Carney , Ambarish Kulkarni , Ahmet Palazoglu
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