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The influences of blood vessels and focused location on temperature distribution during high-intensity focused ultrasound (HIFU) ablation of liver tumors is studied. A three-dimensional acoustics-thermal-fluid coupling model is employed to…

流体动力学 · 物理学 2011-11-15 Maxim A. Solovchuk , Tony W. H. Sheu , Marc Thiriet , Win-Li Lin

High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…

医学物理 · 物理学 2020-07-14 Gajendra Singh , Anup Paul , Himanshu Shekhar , Abhijit Paul

Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…

医学物理 · 物理学 2021-09-14 Yuchan Wang , Yuening Wang , Yuan Jie , Paul Carson

High-Intensity Focused Ultrasound (HIFU) waves are known to induce localized heat to a targeted area during medical treatments. In turn, the rise in temperature influences their speed of propagation. This coupling affects the position of…

偏微分方程分析 · 数学 2022-10-26 Vanja Nikolić , Belkacem Said-Houari

Heat enhancement at the target in a High Intensity Focused Ultrasound (HIFU) field is investigated by considering the effects of the injection of microbubbles in the vicinity of the tumor to be ablated. The interaction between the bubble…

流体动力学 · 物理学 2025-11-27 Aswin Gnanaskandan , Chao-Tsung Hsiao , Georges Chahine

Heating generated by high-intensity focused ultrasound waves is central to many emerging medical applications, including non-invasive cancer therapy and targeted drug delivery. In this study, we aim to gain a fundamental understanding of…

数值分析 · 数学 2025-10-03 Julio Careaga , Benjamin Dörich , Vanja Nikolić

Contactless ultrasound power transfer (UPT) has emerged as one of the promising techniques for wireless power transfer. Physical processes supporting UPT include the vibrations at a transmitting/acoustic source element, acoustic wave…

应用物理 · 物理学 2020-10-09 Aarushi Bhargava , Shima Shahab

A clinical case study of high-intensity focused ultrasound (HIFU) treatment in the uterine fibroid was conducted. During the therapy, poor heating efficacy was observed which could be attributed to several factors such as the local…

医学物理 · 物理学 2019-10-29 Visa Suomi , Antti Viitala , Teija Sainio , Gaber Komar , Roberto Blanco Sequeiros

Model-based treatment planning and exposimetry for high-intensity focused ultrasound (HIFU) requires the numerical simulation of nonlinear ultrasound propagation through heterogeneous and absorbing media. This is a computationally demanding…

医学物理 · 物理学 2014-08-21 Jiri Jaros , Alistair P. Rendell , Bradley E. Treeby

In outside the body HIFU treatment that focused ultrasound beams hit severely with cancer tissue layer especially the soft one, at the time of passage of the body different layers as long as they want to reach tumor, put their own way…

High-intensity focused ultrasound (HIFU) is a promising treatment modality for the non-invasive ablation of pathogenic tissue in many organs. Optimal treatment planning strategies based on high-performance computing methods are expected to…

医学物理 · 物理学 2019-10-03 S. R. Haqshenas , P. Gélat , E. van 't Wout , T. Betcke , N. Saffari

Thermoacoustics, the interaction between heat and acoustic waves, is used in a wide range of advanced technological applications. Conversion of ultrasound waves into heat is employed in medical applications, including tumor ablation.…

Starting from the linear flow of homogeneous fluid, five modes are defined as eigenvectors of the basic system of conservation laws. Quasi-plane geometry is considered. Projectors that separate overall perturbation of the fluid into…

流体动力学 · 物理学 2016-09-08 Anna Perelomova

Standing acoustic waves have been known to generate Eulerian time-mean 'streaming' flows at least since the seminal investigation of Lord Rayleigh in the 1880s. Nevertheless, a recent body of numerical and experimental evidence has shown…

流体动力学 · 物理学 2024-10-10 Jacques Abdul Massih , Remil Mushthaq , Guillaume Michel , Gregory P. Chini

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

医学物理 · 物理学 2020-07-29 Abhijit Paul , Anup Paul

We investigate a nonlinear multiphysics model motivated by ultrasound-enhanced drug delivery. The acoustic pressure field is modeled by Westervelt's quasilinear wave equation to adequately capture the nonlinear effects in ultrasound…

偏微分方程分析 · 数学 2024-12-11 Julio Careaga , Vanja Nikolić , Belkacem Said-Houari

In high intensity focused ultrasound (HIFU) systems using non-ionizing methods in cancer treatment, if the device is applied to the body externally, the HIFU beam can damage nearby healthy tissues and burn skin due to lack of knowledge…

We are interested in shape sensitivity analysis for an optimization problem arising in medical applications of high intensity focused ultrasound. The goal is to find the optimal shape of a focusing acoustic lens so that the desired acoustic…

最优化与控制 · 数学 2015-06-10 Vanja Nikolic , Barbara Kaltenbacher

In various biomedical applications, precise focusing of nonlinear ultrasonic waves is crucial for efficiency and safety of the involved procedures. This work analyzes a class of shape optimization problems constrained by general…

最优化与控制 · 数学 2022-06-08 Mostafa Meliani , Vanja Nikolić

We study the emission and dissipation of acoustic waves from cool dense clouds in pressure equilibrium with a hot, volume-filling dilute gas component. In our model, the clouds are exposed to a source of ionizing radiation whose flux level…

天体物理学 · 物理学 2011-02-11 Doron Chelouche
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