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Detecting associations between microbial compositions and sample characteristics is one of the most important tasks in microbiome studies. Most of the existing methods apply univariate models to single microbial species separately, with…

统计方法学 · 统计学 2021-03-18 Boyu Ren , Sergio Bacallado , Stefano Favaro , Tommi Vatanen , Curtis Huttenhower , Lorenzo Trippa

High-dimensional compositional data arise naturally in many applications such as metagenomic data analysis. The observed data lie in a high-dimensional simplex, and conventional statistical methods often fail to produce sensible results due…

统计方法学 · 统计学 2016-01-19 Yuanpei Cao , Wei Lin , Hongzhe Li

We propose a way to remove the bias of a Poisson regression when the subjects are partially observed. In this paper we address this issue under certain assumptions about the missing-data generating process. We fix the total number of…

统计理论 · 数学 2014-07-08 Seyed Jalil Kazemitabar

The Nested Dirichlet Distribution (NDD) provides a flexible alternative to the Dirichlet distribution for modeling compositional data, relaxing constraints on component variances and correlations through a hierarchical tree structure. While…

统计方法学 · 统计学 2026-01-16 Jacob A. Turner , Monnie McGee , Bianca A. Luedeker

Citations are increasingly used for research evaluations. It is therefore important to identify factors affecting citation scores that are unrelated to scholarly quality or usefulness so that these can be taken into account. Regression is…

数字图书馆 · 计算机科学 2015-11-02 Mike Thelwall , Paul Wilson

Count data take on non-negative integer values and are challenging to properly analyze using standard linear-Gaussian methods such as linear regression and principal components analysis. Generalized linear models enable direct modeling of…

统计方法学 · 统计学 2020-01-14 F. William Townes

This paper describes a compound Poisson-based random effects structure for modeling zero-inflated data. Data with large proportion of zeros are found in many fields of applied statistics, for example in ecology when trying to model and…

应用统计 · 统计学 2009-07-29 Marie-Pierre Etienne , Eric Parent , Benoit Hugues , Bernier Jacques

A shape optimization problem subject to an elliptic equation in the presence of missing data on the Dirichlet boundary condition is considered. It is formulated by optimizing the deformation field that varies the spatial domain where the…

最优化与控制 · 数学 2025-08-19 Karl Kunisch , John Sebastian H. Simon

In his 1986 book, Aitchison explains that compositional data is regularly mishandled in statistical analyses, a pattern that continues to this day. The Dirichlet Type I distribution is a multivariate distribution commonly used to model a…

统计理论 · 数学 2018-04-06 Sean van der Merwe , Daan de Waal

Multivariate categorical data nested within households often include reported values that fail edit constraints---for example, a participating household reports a child's age as older than his biological parent's age---as well as missing…

统计方法学 · 统计学 2018-09-21 Olanrewaju Akande , Andrés Barrientos , Jerome P. Reiter

One important problem in microbiome analysis is to identify the bacterial taxa that are associated with a response, where the microbiome data are summarized as the composition of the bacterial taxa at different taxonomic levels. This paper…

应用统计 · 统计学 2016-03-04 Pixu Shi , Anru Zhang , Hongzhe Li

Zero adjusted regression models are used to fit variables that are discrete at zero and continuous at some interval of the positive real numbers. Diagnostic analysis in these models is usually performed using the randomized quantile…

Regression with compositional response or covariates, or even regression between parts of a composition, is frequently employed in social sciences. Among other possible applications, it may help to reveal interesting features in time…

Compositional data arise when count observations are normalised into proportions adding up to unity. To allow use of standard statistical methods, compositional proportions can be mapped from the simplex into the Euclidean space through the…

统计方法学 · 统计学 2025-07-04 Noora Kartiosuo , Joni Virta , Jaakko Nevalainen , Olli Raitakari , Kari Auranen

We propose a method to distinguish causal influence from hidden confounding in the following scenario: given a target variable Y, potential causal drivers X, and a large number of background features, we propose a novel criterion for…

机器学习 · 统计学 2022-02-07 You-Lin Chen , Lenon Minorics , Dominik Janzing

Microbiome data are complex in nature, involving high dimensionality, compositionally, zero inflation, and taxonomic hierarchy. Compositional data reside in a simplex that does not admit the standard Euclidean geometry. Most existing…

统计方法学 · 统计学 2020-11-12 Gen Li , Yan Li , Kun Chen

We extend conformal prediction methodology beyond the case of exchangeable data. In particular, we show that a weighted version of conformal prediction can be used to compute distribution-free prediction intervals for problems in which the…

统计方法学 · 统计学 2020-07-08 Ryan J. Tibshirani , Rina Foygel Barber , Emmanuel J. Candes , Aaditya Ramdas

Simplicial-simplicial regression refers to the regression setting where both the responses and predictor variables lie within the simplex space, i.e. they are compositional. For this setting, constrained least squares, where the regression…

统计方法学 · 统计学 2024-12-24 Michail Tsagris

A compositional tree refers to a tree structure on a set of random variables where each random variable is a node and composition occurs at each non-leaf node of the tree. As a generalization of compositional data, compositional trees…

统计方法学 · 统计学 2021-04-20 Bingkai Wang , Brian S. Caffo , Xi Luo , Chin-Fu Liu , Andreia V. Faria , Michael I. Miller , Yi Zhao

In practice functional data are sampled on a discrete set of observation points and often susceptible to noise. We consider in this paper the setting where such data are used as explanatory variables in a regression problem. If the primary…

统计方法学 · 统计学 2021-12-14 Siegfried Hörmann , Fatima Jammoul