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Finding optimal evolutionary trees from sequence data is typically an intractable problem, and there is usually no way of knowing how close to optimal the best tree from some search truly is. The problem would seem to be particularly acute…

种群与进化 · 定量生物学 2013-06-07 Dietrich Radel , Andreas Sand , Mike Steel

As an alternative to parsimony analyses, stochastic models have been proposed (Lewis, 2001), (Nylander, et al., 2004) for morphological characters, so that maximum likelihood or Bayesian analyses may be used for phylogenetic inference. A…

种群与进化 · 定量生物学 2009-12-20 Elizabeth S. Allman , Mark T. Holder , John A. Rhodes

In phylogenetic analysis, for non-molecular data, particularly morphology, parsimony optimization is the most commonly employed approach. In the past and present application of the parsimony principle, extra step numbers have been added…

种群与进化 · 定量生物学 2016-10-12 Yue Zhang

Applying a method to reconstruct a phylogenetic tree from random data provides a way to detect whether that method has an inherent bias towards certain tree `shapes'. For maximum parsimony, applied to a sequence of random 2-state data, each…

种群与进化 · 定量生物学 2014-06-03 Mareike Fischer , Michelle Galla , Lina Herbst , Mike Steel

One of the main aims of phylogenetics is the reconstruction of the correct evolutionary tree when data concerning the underlying species set are given. These data typically come in the form of DNA, RNA or protein alignments, which consist…

种群与进化 · 定量生物学 2019-03-22 Mareike Fischer

How do phylogenetic reconstruction algorithms go astray when they return incorrect trees? This simple question has not been answered in detail, even for maximum parsimony (MP), the simplest phylogenetic criterion. Understanding MP has…

In phylogenetic studies, biologists often wish to estimate the ancestral discrete character state at an interior vertex $v$ of an evolutionary tree $T$ from the states that are observed at the leaves of the tree. A simple and fast…

种群与进化 · 定量生物学 2018-05-03 Lina Herbst , Thomas Li , Mike Steel

One of the main aims in phylogenetics is the estimation of ancestral sequences based on present-day data like, for instance, DNA alignments. One way to estimate the data of the last common ancestor of a given set of species is to first…

种群与进化 · 定量生物学 2017-02-07 Lina Herbst , Mareike Fischer

Tuffley and Steel (1997) proved that Maximum Likelihood and Maximum Parsimony methods in phylogenetics are equivalent for sequences of characters under a simple symmetric model of substitution with no common mechanism. This result has been…

种群与进化 · 定量生物学 2009-07-06 Mareike Fischer , Bhalchandra D. Thatte

Estimating phylogenetic trees, which depict the relationships between different species, from aligned sequence data (such as DNA, RNA, or proteins) is one of the main aims of evolutionary biology. However, tree reconstruction criteria like…

种群与进化 · 定量生物学 2024-10-02 Mareike Fischer

The so-called binary perfect phylogeny with persistent characters has recently been thoroughly studied in computational biology as it is less restrictive than the well known binary perfect phylogeny. Here, we focus on the notion of (binary)…

种群与进化 · 定量生物学 2020-03-30 Kristina Wicke , Mareike Fischer

Phylogenetic mixture models are statistical models of character evolution allowing for heterogeneity. Each of the classes in some unknown partition of the characters may evolve by different processes, or even along different trees. The…

种群与进化 · 定量生物学 2010-11-19 John A. Rhodes , Seth Sullivant

Phylogenetic (i.e. leaf-labeled) trees play a fundamental role in evolutionary research. A typical problem is to reconstruct such trees from data like DNA alignments (whose columns are often referred to as characters), and a simple…

种群与进化 · 定量生物学 2022-09-08 Mareike Fischer

Evolution is a process that is influenced by various environmental factors, e.g. the interactions between different species, genes, and biogeographical properties. Hence, it is interesting to study the combined evolutionary history of…

定量方法 · 定量生物学 2013-08-02 Nicolas Wieseke , Matthias Bernt , Martin Middendorf

Phylogenetic trees are leaf-labelled trees used to model the evolution of species. In practice it is not uncommon to obtain two topologically distinct trees for the same set of species, and this motivates the use of distance measures to…

数据结构与算法 · 计算机科学 2026-03-24 David Mestel , Steven Chaplick , Steven Kelk , Ruben Meuwese

Phylogenetic networks are used to display the relationship of different species whose evolution is not treelike, which is the case, for instance, in the presence of hybridization events or horizontal gene transfers. Tree inference methods…

种群与进化 · 定量生物学 2014-05-02 Mareike Fischer , Leo van Iersel , Steven Kelk , Celine Scornavacca

Maximum parsimony is one of the most frequently-discussed tree reconstruction methods in phylogenetic estimation. However, in recent years it has become more and more apparent that phylogenetic trees are often not sufficient to describe…

种群与进化 · 定量生物学 2016-10-25 Christopher Bryant , Mareike Fischer , Simone Linz , Charles Semple

In this paper, we investigate a conjecture by von Haeseler concerning the Maximum Parsimony method for phylogenetic estimation, which was published by the Newton Institute in Cambridge on a list of open phylogenetic problems in 2007. This…

种群与进化 · 定量生物学 2010-07-30 Mareike Fischer

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

种群与进化 · 定量生物学 2012-12-11 Yun Yu , Luay Nakhleh

Deciding whether there is a single tree -a supertree- that summarizes the evolutionary information in a collection of unrooted trees is a fundamental problem in phylogenetics. We consider two versions of this question: agreement and…

离散数学 · 计算机科学 2013-08-02 Sudheer Vakati , David Fernández-Baca
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