相关论文: Optimizing control of HIV in Kenya

We propose a population model for HIV-TB co-infection dynamics by considering treatments for HIV infection, active tuberculosis and co-infection. The HIV only and TB only models are analyzed separately, as well as full model. The basic…

Dynamic models have been successfully used in producing estimates of HIV epidemics at national level, due to their epidemiological nature and their ability to simultaneously estimate prevalence, incidence, and mortality rates. Recently, HIV…

The concentration of CD4 T-lymphocytes (CD4 count), in a person's plasma is widely used to decide when to start HIV-positive people on anti-retroviral therapy (ART) and to predict the impact of ART on the future course of HIV and…

The COVID-19 pandemic has plagued the world for months. The U.S. has taken measures to counter it. On a daily basis, newly confirmed cases have been reported. In the early days, these numbers showed an increasing trend. Recently, the…

The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the…

Small area estimation (SAE) entails estimating characteristics of interest for domains, often geographical areas, in which there may be few or no samples available. SAE has a long history and a wide variety of methods have been suggested,…

COVID-19 pandemic has affected each and every country's health service and plunged refugees into the most desperate conditions. The plight of Rohingya refugees is among the harshest. It has severely affected their existing HIV/STI…

Molecular HIV Surveillance (MHS) has been described as key to enabling rapid responses to HIV outbreaks. It operates by linking individuals with genetically similar viral sequences, which forms a network. A major limitation of MHS is that…

We revisit the SICA (Susceptible-Infectious-Chronic-AIDS) mathematical model for transmission dynamics of the human immunodeficiency virus (HIV) with varying population size in a homogeneously mixing population. We consider SICA models…

Since the early 2000s, evidence has accumulated for a significant differential effect of first-line antiretroviral therapy (ART) regimens on human immunodeficiency virus (HIV) viral load suppression. This finding was replicated in our data…

Despite its endemic nature as well as the recent outbreaks, information on the opportunistic DENV in Anambra state has been sparse. This study thus aimed to give seroepidemiological evidence of past dengue virus infection among HIV-infected…

Methods are lacking to handle the problem of survival analysis in the presence of an interval-censored covariate, specifically the case in which the conditional hazard of the primary event of interest depends on the occurrence of a…

Aim of this manuscript is to show a simple method to infer the time-course of new COVID-19 infections (the most important information in order to establish the effect of containment strategies) from available aggregated data, such as number…

This paper examines the pattern of HIV risk behaviors among male jail detainees. From multivariate analyses of baseline data from an HIV intervention study of ours, we find that: (1) cocaine use, heroin use and multiple sexual partners; and…

Voluntary medical male circumcision (VMMC) reduces the risk of male HIV acquisition by 60%. Programmes to provide male circumcision (MC) to prevent HIV infection have been introduced in sub-Saharan African countries with high HIV burden.…

The government's effort to alleviate HIV stigma has been justified by the suppression effect of stigma on the HIV testing rate. Nevertheless, the deterrence effect of stigma on undesirable sexual behaviours has long been overlooked. This…

Network scientists have proposed that infectious diseases involving person-to-person transmission may be effectively halted by targeting interventions at a minority of highly connected individuals. Can this strategy be effective in…

The epidemic spreading has been studied for years by applying the mean-field approach in both homogeneous case, where each node may get infected by an infected neighbor with the same rate, and heterogeneous case, where the infection rates…

Background As more regions approach malaria elimination, understanding how different interventions interact to reduce transmission becomes critical. The Lake Kariba area of Southern Province, Zambia, is part of a multi-country elimination…

At the time of this article, COVID-19 has been transmitted to more than 42 million people and resulted in more than 673,000 deaths across the United States. Throughout this pandemic, public health authorities have monitored the results of…