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Graph spanners are sparse subgraphs that faithfully preserve the distances in the original graph up to small stretch. Spanner have been studied extensively as they have a wide range of applications ranging from distance oracles, labeling…

数据结构与算法 · 计算机科学 2018-05-16 Merav Parter , Eylon Yogev

The unsupervised learning of community structure, in particular the partitioning vertices into clusters or communities, is a canonical and well-studied problem in exploratory graph analysis. However, like most graph analyses the…

机器学习 · 计算机科学 2020-07-27 Benjamin W. Priest , Alec Dunton , Geoffrey Sanders

We present Meraculous2, an update to the Meraculous short-read assembler that includes (1) handling of allelic variation using "bubble" structures within the de Bruijn graph, (2) improved gap closing, and (3) an improved scaffolding…

数据结构与算法 · 计算机科学 2017-11-09 Jarrod A. Chapman , Isaac Y. Ho , Eugene Goltsman , Daniel S. Rokhsar

Computational methods for discovering patterns of local correlations in sequences are important in computational biology. Here we show how to determine the optimal partitioning of aligned sequences into non-overlapping segments such that…

计算工程、金融与科学 · 计算机科学 2012-06-26 Joseph Bockhorst , Nebojsa Jojic

Frequent pattern mining is a flagship problem in data mining. In its most basic form, it asks for the set of substrings of a given string $S$ of length $n$ that occur at least $\tau$ times in $S$, for some integer $\tau\in[1,n]$. We…

All traditional methods of computing shortest paths depend upon edge-relaxation where the cost of reaching a vertex from a source vertex is possibly decreased if that edge is used. We introduce a method which maintains lower bounds as well…

分布式、并行与集群计算 · 计算机科学 2018-12-31 Vijay K. Garg

Subgraph counting aims to count the occurrences of a subgraph template T in a given network G. The basic problem of computing structural properties such as counting triangles and other subgraphs has found applications in diverse domains.…

分布式、并行与集群计算 · 计算机科学 2019-03-12 Langshi Chen , Jiayu Li , Ariful Azad , Lei Jiang , Madhav Marathe , Anil Vullikanti , Andrey Nikolaev , Egor Smirnov , Ruslan Israfilov , Judy Qiu

The paper investigates the computational problem of predicting RNA secondary structures. The general belief is that allowing pseudoknots makes the problem hard. Existing polynomial-time algorithms are heuristic algorithms with no…

计算工程、金融与科学 · 计算机科学 2007-05-23 Samuel Ieong , Ming-Yang Kao , Tak-Wah Lam , Wing-Kin Sung , Siu-Ming Yiu

The paper addresses challenges in storing and retrieving sequences in contexts like anomaly detection, behavior prediction, and genetic information analysis. Associative Knowledge Graphs (AKGs) offer a promising approach by leveraging…

人工智能 · 计算机科学 2025-09-11 Przemysław Stokłosa , Janusz A. Starzyk , Paweł Raif , Adrian Horzyk , Marcin Kowalik

Dual graphs have been applied to model RNA secondary structures with pseudoknots, or intertwined base pairs. In previous works, a linear-time algorithm was introduced to partition dual graphs into maximally connected components called…

生物大分子 · 定量生物学 2021-09-09 Louis Petingi

A de Bruijn sequence of order n over a k-symbol alphabet is a circular sequence where each length-n sequence occurs exactly once. We present a way of extending de Bruijn sequences by adding a new symbol to the alphabet: the extension is…

离散数学 · 计算机科学 2020-11-23 Verónica Becher , Lucas Cortés

Characterizing the differential excision of mRNA is critical for understanding the functional complexity of a cell or tissue, from normal developmental processes to disease pathogenesis. Most transcript reconstruction methods infer…

定量方法 · 定量生物学 2022-11-15 Marjan Hosseini , Devin McConnell , Derek Aguiar

Images conveniently capture the result of physical processes, representing rich source of information for data driven medicine, engineering, and science. The modeling of an image as a graph allows the application of graph-based algorithms…

数据结构与算法 · 计算机科学 2022-10-28 Diego Ulisse Pizzagalli , Rolf Krause

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

定量方法 · 定量生物学 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

Event-based cameras are attracting significant interest as they provide rich edge information, high dynamic range, and high temporal resolution. Many state-of-the-art event-based algorithms rely on splitting the events into fixed groups,…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Jiahang Cao , Mingyuan Sun , Ziqing Wang , Hao Cheng , Qiang Zhang , Shibo Zhou , Renjing Xu

Achieving optimal semantic segmentation with frame-based vision sensors poses significant challenges for real-time systems like UAVs and self-driving cars, which require rapid and precise processing. Traditional frame-based methods often…

计算机视觉与模式识别 · 计算机科学 2025-02-27 D. Hareb , J. Martinet , B. Miramond

Research on Graph Structure Learning (GSL) provides key insights for graph-based clustering, yet current methods like Graph Neural Networks (GNNs), Graph Attention Networks (GATs), and contrastive learning often rely heavily on the original…

机器学习 · 计算机科学 2025-05-21 Jingyun Zhang , Hao Peng , Li Sun , Guanlin Wu , Chunyang Liu , Zhengtao Yu

The problem of identifying the maximum edge biclique in bipartite graphs has attracted considerable attention in bipartite graph analysis, with numerous real-world applications such as fraud detection, community detection, and online…

数据结构与算法 · 计算机科学 2025-06-23 Donghang Cui , Ronghua Li , Qiangqiang Dai , Hongchao Qin , Guoren Wang

Sampling-based algorithms are classical approaches to perform Bayesian inference in inverse problems. They provide estimators with the associated credibility intervals to quantify the uncertainty on the estimators. Although these methods…

统计方法学 · 统计学 2023-11-28 Pierre-Antoine Thouvenin , Audrey Repetti , Pierre Chainais

This work addresses the challenge of using a deep learning model to prune graphs and the ability of this method to integrate explainability into spatio-temporal problems through a new approach. Instead of applying explainability to the…

机器学习 · 计算机科学 2025-10-14 Javier García-Sigüenza , Mirco Nanni , Faraón Llorens-Largo , José F. Vicent