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In this paper, a contrastive evaluation of massively parallel implementations of suffix tree and suffix array to accelerate genome sequence matching are proposed based on Intel Core i7 3770K quad-core and NVIDIA GeForce GTX680 GPU. Besides…

数据结构与算法 · 计算机科学 2015-05-05 Gang Liao , Qi Sun , Longfei Ma , Sha Ding , Wen Xie

Early hardware limitations of GPU (lack of synchronization primitives and limited memory caching mechanisms) can make GPU-based computation inefficient. Now Bio-technologies bring more chances to Bioinformatics and Biological Engineering.…

分布式、并行与集群计算 · 计算机科学 2014-10-29 YuKun Zhong , BaoQiu Wang , JianBiao Lin , Chen Tao , Che Nian , Xie Wen

Since the release of human genome sequences, one of the most important research issues is about indexing the genome sequences, and the suffix tree is most widely adopted for that purpose. The traditional suffix tree construction algorithms…

数据库 · 计算机科学 2015-05-20 Woong-Kee Loh , Yang-Sae Moon , Wookey Lee

Analysis of DNA samples is an important step in forensics, and the speed of analysis can impact investigations. Comparison of DNA sequences is based on the analysis of short tandem repeats (STRs), which are short DNA sequences of 2-5 base…

性能 · 计算机科学 2018-03-07 Siddharth Samsi , Brian Helfer , Jeremy Kepner , Albert Reuther , Darrell O. Ricke

The prevalent technique for DNA sequencing consists of two main steps: shotgun sequencing, where many randomly located fragments, called reads, are extracted from the overall sequence, followed by an assembly algorithm that aims to…

基因组学 · 定量生物学 2016-01-28 Shirshendu Ganguly , Elchanan Mossel , Miklos Z. Racz

The cost of DNA sequencing has dropped exponentially over the past decade, making genomic data accessible to a growing number of scientists. In bioinformatics, localization of short DNA sequences (reads) within large genomic sequences is…

基因组学 · 定量生物学 2021-06-16 Robin Kobus , André Müller , Daniel Jünger , Christian Hundt , Bertil Schmidt

DNA sequencing is the basic workhorse of modern day biology and medicine. Shotgun sequencing is the dominant technique used: many randomly located short fragments called reads are extracted from the DNA sequence, and these reads are…

信息论 · 计算机科学 2013-02-15 Abolfazl Motahari , Guy Bresler , David Tse

The Laue diffraction microscopy experiment uses the polychromatic Laue micro-diffraction technique to examine the structure of materials with sub-micron spatial resolution in all three dimensions. During this experiment, local…

数据分析、统计与概率 · 物理学 2022-02-01 Ke Yue , Schwarz Nicholas , Tischler Jonathan Z

Genomics is changing our understanding of humans, evolution, diseases, and medicines to name but a few. As sequencing technology is developed collecting DNA sequences takes less time thereby generating more genetic data every day. Today the…

定量方法 · 定量生物学 2020-07-29 Sahand Salamat , Tajana Rosing

The suffix array is a data structure that finds numerous applications in string processing problems for both linguistic texts and biological data. It has been introduced as a memory efficient alternative for suffix trees. The suffix array…

数据结构与算法 · 计算机科学 2013-07-05 Sanguthevar Rajasekaran , Marius Nicolae

Analysis of processing time and similarity of images generated between CPU and GPU architectures and sequential and parallel programming. For image processing a computer with AMD FX-8350 processor and an Nvidia GTX 960 Maxwell GPU was used,…

In array-based DNA synthesis, multiple strands of DNA are synthesized in parallel to reduce the time cost from the sum of their lengths to the length their shortest common supersequences. To maximize the amount of information that can be…

信息论 · 计算机科学 2024-05-29 Hsin-Po Wang , Chi-Wei Chin

Given natural limitations on the length DNA sequences, designing phylogenetic reconstruction methods which are reliable under limited information is a crucial endeavor. There have been two approaches to this problem: reconstructing partial…

数据结构与算法 · 计算机科学 2008-12-10 Radu Mihaescu , Cameron Hill , Satish Rao

The suffix tree is a data structure for indexing strings. It is used in a variety of applications such as bioinformatics, time series analysis, clustering, text editing and data compression. However, when the string and the resulting suffix…

数据库 · 计算机科学 2011-10-03 Essam Mansour , Amin Allam , Spiros Skiadopoulos , Panos Kalnis

Rapid analysis of DNA sequences is important in preventing the evolution of different viruses and bacteria during an early phase, early diagnosis of genetic predispositions to certain diseases (cancer, cardiovascular diseases), and in DNA…

分布式、并行与集群计算 · 计算机科学 2015-09-07 Suejb Memeti , Sabri Pllana

The synthesis of DNA strands remains the most costly part of the DNA storage system. Thus, to make DNA storage system more practical, the time and materials used in the synthesis process have to be optimized. We consider the most common…

信息论 · 计算机科学 2023-05-15 Johan Chrisnata , Han Mao Kiah , Van Long Phuoc Pham

In this paper we will describe a new approach on the well-known suffix-array algorithm using Big Table Data Technology. We will demonstrate how it is possible to refactor a well-known algorithm coupled by taking advantage of an…

数据库 · 计算机科学 2020-03-26 Piero Giacomelli

We introduce a parallel algorithmic architecture for metagenomic sequence assembly, termed MetaPar, which allows for significant reductions in assembly time and consequently enables the processing of large genomic datasets on computers with…

定量方法 · 定量生物学 2013-11-18 Minji Kim , Jonathan G. Ligo , Amin Emad , Farzad Farnoud , Olgica Milenkovic , Venugopal V. Veeravalli

Optimizing deep learning models is generally performed in two steps: (i) high-level graph optimizations such as kernel fusion and (ii) low level kernel optimizations such as those found in vendor libraries. This approach often leaves…

机器学习 · 计算机科学 2021-03-08 Pratik Fegade , Tianqi Chen , Phillip B. Gibbons , Todd C. Mowry

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

硬件体系结构 · 计算机科学 2021-11-04 Damla Senol Cali
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