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Computational identification of promoters is notoriously difficult as human genes often have unique promoter sequences that provide regulation of transcription and interaction with transcription initiation complex. While there are many…

基因组学 · 定量生物学 2018-10-04 Ramzan Umarov , Hiroyuki Kuwahara , Yu Li , Xin Gao , Victor Solovyev

Biologically-inspired methods such as evolutionary algorithms and neural networks are proving useful in the field of information fusion. Artificial Immune Systems (AISs) are a biologically-inspired approach which take inspiration from the…

人工智能 · 计算机科学 2010-07-05 Jamie Twycross , Uwe Aickelin

This paper proposes a comprehensive analysis of existing concepts coming from different disciplines tackling the notion of intelligence, namely psychology and engineering, and from disciplines aiming to regulate AI innovations, namely AI…

人工智能 · 计算机科学 2021-05-10 Gauthier Chassang , Mogens Thomsen , Pierre Rumeau , Florence Sèdes , Alejandra Delfin

Rapid development of modern sequencing platforms enabled an unprecedented growth of protein families databases. The abundance of sets composed of hundreds of thousands sequences is a great challenge for multiple sequence alignment…

基因组学 · 定量生物学 2017-03-03 Sebastin Deorowicz , Agnieszka Debudaj-Grabysz , Adam Gudys

As a potential non-invasive biomarker for ischaemic stroke, intracranial arterial calcification (IAC) could be used for stroke risk assessment on CT head scans routinely acquired for other reasons (e.g. trauma, confusion). Artificial…

The recent advancement of foundation models (FMs) has brought about a paradigm shift, revolutionizing various sectors worldwide. The popular optimizers used to train these models are stochastic gradient descent-based algorithms, which face…

机器学习 · 计算机科学 2026-01-06 Shenglong Zhou , Ouya Wang , Ziyan Luo , Yongxu Zhu , Geoffrey Ye Li

With the rapid development of high-throughput sequencing platforms, an increasing number of omics technologies, such as genomics, metabolomics, and transcriptomics, are being applied to disease genetics research. However, biological data…

基因组学 · 定量生物学 2024-12-18 Lei Xin , Caiyun Huang , Hao Li , Shihong Huang , Yuling Feng , Zhenglun Kong , Zicheng Liu , Siyuan Li , Chang Yu , Fei Shen , Hao Tang

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

计算机视觉与模式识别 · 计算机科学 2021-11-30 Simon Graham , Mostafa Jahanifar , Quoc Dang Vu , Giorgos Hadjigeorghiou , Thomas Leech , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Selecting an effective docking algorithm is highly context-dependent, and no single method performs reliably across structural, chemical, or protocol regimes. We introduce MolAS, a lightweight algorithm selection system that predicts…

定量方法 · 定量生物学 2025-12-03 Jiabao Brad Wang , Siyuan Cao , Hongxuan Wu , Yiliang Yuan , Mustafa Misir

Causal discovery is a crucial initial step in establishing causality from empirical data and background knowledge. Numerous algorithms have been developed for this purpose. Among them, the score-matching method has demonstrated superior…

机器学习 · 统计学 2026-04-14 Hao Chen , Kai Yi

This article discusses the integration of the Artificial Bee Colony (ABC) algorithm with two supervised learning methods, namely Artificial Neural Networks (ANNs) and Adaptive Network-based Fuzzy Inference System (ANFIS), for feature…

系统与控制 · 电气工程与系统科学 2025-01-14 Amir Pouya Masoumi , Leo Creedon , Ramen Ghosh , Nimra Munir , Ross McMorrow , Marion McAfee

Independent component analysis (ICA) has been used in many applications, including self-interference cancellation for in-band full-duplex wireless systems and anomaly detection in industrial internet of things. This paper presents a…

信号处理 · 电气工程与系统科学 2022-05-03 Hsi-Hung Lu , Chung-An Shen , Mohammed E. Fouda , Ahmed M. Eltawil

The robust PCA problem, wherein, given an input data matrix that is the superposition of a low-rank matrix and a sparse matrix, we aim to separate out the low-rank and sparse components, is a well-studied problem in machine learning. One…

机器学习 · 计算机科学 2017-07-06 U. N. Niranjan , Arun Rajkumar , Theja Tulabandhula

Melanoma, one of most dangerous types of skin cancer, re-sults in a very high mortality rate. Early detection and resection are two key points for a successful cure. Recent research has used artificial intelligence to classify melanoma and…

计算机视觉与模式识别 · 计算机科学 2020-08-31 Cong Tri Pham , Mai Chi Luong , Dung Van Hoang , Antoine Doucet

Network security has become the biggest concern in the area of cyber security because of the exponential growth in computer networks and applications. Intrusion detection plays an important role in the security of information systems or…

密码学与安全 · 计算机科学 2022-10-07 Zareen Fatima , Arshad Ali

In post genomic era with the advent of new technologies a huge amount of complex molecular data are generated with high throughput. The management of this biological data is definitely a challenging task due to complexity and heterogeneity…

数据库 · 计算机科学 2014-03-13 Ananya Bose , Suprativ Saha

The cell-free integrated sensing and communication (CF-ISAC) system, which effectively mitigates intra-cell interference and provides precise sensing accuracy, is a promising technology for future 6G networks. However, to fully capitalize…

信号处理 · 电气工程与系统科学 2025-08-28 Yue Xiu , Yang Zhao , Ran Yang , Wanting Lyu , Dusit Niyato , Dong In Kim , Guangyi Liu , Ning Wei

Locating the promoter region in DNA sequences is of paramount importance in the field of bioinformatics. This is a problem widely studied in the literature, however, not yet fully resolved. Some researchers have presented remarkable results…

机器学习 · 计算机科学 2021-12-08 Lauro Moraes , Pedro Silva , Eduardo Luz , Gladston Moreira

An important objective in computational biology is the efficient integration of multi-omics data. The task of integration comes with challenges: multi-omics data are most often unpaired (requiring diagonal integration), partially labeled…

机器学习 · 计算机科学 2025-09-16 Daniel Lepe-Soltero , Thierry Artières , Anaïs Baudot , Paul Villoutreix

Malicious activities in cyberspace have gone further than simply hacking machines and spreading viruses. It has become a challenge for a nations survival and hence has evolved to cyber warfare. Malware is a key component of cyber-crime, and…

密码学与安全 · 计算机科学 2021-07-09 Muhammad Asam , Saddam Hussain Khan , Tauseef Jamal , Umme Zahoora , Asifullah Khan