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Rotors are functional reentry sources identified in clinically relevant cardiac arrhythmias, such as ventricular and atrial fibrillation. Ablation targeting rotor sites has resulted in arrhythmia termination. Recent clinical, experimental…

组织与器官 · 定量生物学 2019-03-06 Nele Vandersickel , Masaya Watanabe , Qian Tao , Jan Fostier , Katja Zeppenfeld , Alexander V Panfilov

Cardiac arrhythmias such as ventricular tachycardia (VT) or ventricular fibrillation (VF) are the leading cause of death in the industrialised world. There is a growing consensus that these arrhythmias arise because of the formation of…

斑图形成与孤子 · 物理学 2007-05-23 T. K. Shajahan , Sitabhra Sinha , Rahul Pandit

Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart makes it incapable of any…

混沌动力学 · 物理学 2009-11-07 Sitabhra Sinha , Ashwin Pande , Rahul Pandit

We develop a deep learning model, ABioSPATH, to predict the one-year risk of ischemic stroke (IS) in atrial fibrillation (AF) patients. The model integrates drug-protein-disease pathways and real-world clinical data of AF patients to…

定量方法 · 定量生物学 2024-08-27 Zhiheng Lyu , Jiannan Yang , Zhongzhi Xu , Weilan Wang , Weibin Cheng , Kwok-Leung Tsui , Gary Tse , Qingpeng Zhang

Atrial fibrillation (AF) is one of the most common arrhythmias with challenging public health implications. Therefore, automatic detection of AF episodes on ECG is one of the essential tasks in biomedical engineering. In this paper, we…

信号处理 · 电气工程与系统科学 2023-10-03 Nikita Markov , Konstantin Ushenin , Yakov Bozhko , Olga Solovyova

Detection of atrial fibrillation (AF), a type of cardiac arrhythmia, is difficult since many cases of AF are usually clinically silent and undiagnosed. In particular paroxysmal AF is a form of AF that occurs occasionally, and has a higher…

神经元与认知 · 定量生物学 2018-05-24 Supreeth P. Shashikumar , Amit J. Shah , Gari D. Clifford , Shamim Nemati

Objective: This work aims at providing a new method for the automatic detection of atrial fibrillation, other arrhythmia and noise on short single lead ECG signals, emphasizing the importance of the interpretability of the classification…

人工智能 · 计算机科学 2021-12-09 Tomás Teijeiro , Constantino A. García , Daniel Castro , Paulo Félix

It has become widely accepted that the most dangerous cardiac arrhythmias are due to re- entrant waves, i.e., electrical wave(s) that re-circulate repeatedly throughout the tissue at a higher frequency than the waves produced by the heart's…

斑图形成与孤子 · 物理学 2009-11-07 Flavio H Fenton , Elizabeth M Cherry , Harold M. Hastings , Steven J. Evans

Atrial Fibrillation is a common form of irregular heart rhythm that can be very dangerous. Our primary goal is to analyze Atrial Fibrillation data within ECGs to develop a model based only on RR-Intervals, or the length between heart-beats,…

定量方法 · 定量生物学 2023-02-16 Georgia Smith , Yishi Wang

The mechanism that maintains atrial fibrillation (AF) remains elusive. One approach to understanding and controlling the mechanism ("AF driver") is to quantify inter-scale information flow from macroscopic to microscopic behaviors of the…

斑图形成与孤子 · 物理学 2018-08-01 Hiroshi Ashikaga , Ryan G. James

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

流体动力学 · 物理学 2016-07-27 Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi , Matteo Anselmino

Atrial fibrillation (AF) is characterized by irregular electrical impulses originating in the atria, which can lead to severe complications and even death. Due to the intermittent nature of the AF, early and timely monitoring of AF is…

声音 · 计算机科学 2024-08-12 Xuanyu Liu , Haoxian Liu , Jiao Li , Zongqi Yang , Yi Huang , Jin Zhang

It has recently been observed that the occurrence of sudden cardiac death has a close statistical relationship with the time of day, viz., ventricular fibrillation is most likely to occur between 12 am-6 am, with 6 pm-12 am being the next…

组织与器官 · 定量生物学 2016-09-30 Pavithraa Seenivasan , Shakti N. Menon , S. Sridhar , Sitabhra Sinha

Atrial fibrillation (AF) is the most common arrhythmia, associated with significant burdens to patients and the healthcare system. The atrioventricular (AV) node plays a vital role in regulating heart rate during AF, but is often…

应用统计 · 统计学 2023-10-18 Mattias Karlsson , Pyotr G Platonov , Sara R. Ulimoen , Frida Sandberg , Mikael Wallman

Atrial fibrillation (AF) is the most prevalent heart arrhythmia. AF manifests on the electrocardiogram (ECG) though irregular beat-to-beat time interval variation, the absence of P-wave and the presence of fibrillatory waves (f-wave). We…

信号处理 · 电气工程与系统科学 2022-08-23 Noam Ben-Moshe , Shany Biton , Joachim A. Behar

Atrial fibrillation (AF) is a major complication following embolic stroke of undetermined source (ESUS), elevating the risk of recurrent stroke and mortality. Early identification is clinically important, yet existing tools face limitations…

机器学习 · 计算机科学 2026-03-18 Yuzhang Xie , Yuhua Wu , Ruiyu Wang , Fadi Nahab , Xiao Hu , Carl Yang

Atrial Fibrillation (AF) is an abnormal heart rhythm which can trigger cardiac arrest and sudden death. Nevertheless, its interpretation is mostly done by medical experts due to high error rates of computerized interpretation. One study…

信号处理 · 电气工程与系统科学 2019-08-20 Yuxi Zhou , Shenda Hong , Junyuan Shang , Meng Wu , Qingyun Wang , Hongyan Li , Junqing Xie

Background. Despite the routine prescription of rate control therapy for atrial fibrillation (AF), clinical evidence demonstrating a heart rate target is lacking. Aim of the present study was to run a mathematical model simulating AF…

Atrial fibrillation (AF) represents the most prevalent type of cardiac arrhythmia for which treatment may require patients to undergo ablation therapy. In this surgery cardiac tissues are locally scarred on purpose to prevent electrical…

图像与视频处理 · 电气工程与系统科学 2025-08-07 Franz Thaler , Darko Stern , Gernot Plank , Martin Urschler

Background: Despite the recent advances in computational fluid dynamics (CFD) techniques applied to blood flow within the left atrium (LA), the relationship between atrial geometry, flow patterns, and blood stasis within the left atrial…