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Modeling stochasticity in gene regulatory networks is an important and complex problem in molecular systems biology. To elucidate intrinsic noise, several modeling strategies such as the Gillespie algorithm have been used successfully. This…

分子网络 · 定量生物学 2013-01-18 David Murrugarra , Alan Veliz-Cuba , Boris Aguilar , Seda Arat , Reinhard Laubenbacher

The effect of external fluctuations on the formation of spatial patterns is analysed by means of a stochastic Swift-Hohenberg model with multiplicative space-correlated noise. Numerical simulations in two dimensions show a shift of the…

凝聚态物理 · 物理学 2009-10-28 J. Garcia-Ojalvo , J. M. Sancho

This paper formulates two 3D stochastic differential equations (SDEs) of two microbial populations in a chemostat competing over a single substrate. The two models have two distinct noise sources. One is general noise whereas the other is…

动力系统 · 数学 2017-06-23 Dimitrios Voulgarelis , Ajoy Valayudhan , Frank Smith

In an experimental study of single enzyme reactions, it has been proposed that the rate constants of the enzymatic reactions fluctuate randomly, according to a given distribution. To quantify the uncertainty arising from random rate…

定量方法 · 定量生物学 2012-02-07 Chia Ying Lee

Spatial and temporal noise power spectra of stripe patterns are investigated, using as a model a Swift-Hohenberg equation with a stochastic term. In particular, the analytical and numerical investigations show: 1) the temporal noise spectra…

软凝聚态物质 · 物理学 2009-11-07 K. Staliunas

Stochastic exponential growth is observed in a variety of contexts, including molecular autocatalysis, nuclear fission, population growth, inflation of the universe, viral social media posts, and financial markets. Yet literature on…

统计力学 · 物理学 2017-06-14 Dan Pirjol , Farshid Jafarpour , Srividya Iyer-Biswas

Moving boundary problems allow to model systems with phase transition at an inner boundary. Driven by problems in economics and finance, in particular modeling of limit order books, we consider a stochastic and non-linear extension of the…

概率论 · 数学 2018-10-31 Marvin S. Mueller

Enzyme kinetics has historically been described by deterministic models, with the Michaelis-Menten (MM) equation serving as a paradigm. However, recent experimental and theoretical advances have made it clear that stochastic fluctuations,…

分子网络 · 定量生物学 2025-04-08 Jiaji Qu , Malini Rajbhandari

We study stochastic evolution equations driven by Gaussian noise. The key features of the model are that the operators in the deterministic and stochastic parts can have the same order and the noise can be time-only, space-only, or…

概率论 · 数学 2007-09-20 S. V. Lototsky , B. L. Rozovskii

System-environment interactions are intrinsically nonlinear and dependent on the interplay between many degrees of freedom. The complexity may be even more pronounced when one aims to describe biologically motivated systems. In that case,…

统计力学 · 物理学 2014-07-07 L. A. da Silva , E. H. Colombo , C. Anteneodo

We study generalised rock-paper-scissors models with an arbitrary odd number N \geq 5 of species, among which n are weak, with 2 \leq n \leq (N-1)/2. Because of the species' weakness, the probability of individuals conquering territory in…

种群与进化 · 定量生物学 2023-06-06 J. Menezes , R. Barbalho

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

动力系统 · 数学 2025-10-03 Abdallah Alsammani

Fluctuating environments pose tremendous challenges to bacterial populations. It is observed in numerous bacterial species that individual cells can stochastically switch among multiple phenotypes for the population to survive in rapidly…

分子网络 · 定量生物学 2015-01-20 Chen Jia , Min-Ping Qian , Yu Kang , Da-Quan Jiang

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

统计力学 · 物理学 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

This paper considers the behavior of discrete and continuous mathematical models for gene expression in the presence of transcriptional/translational bursting. We treat this problem in generality with respect to the distribution of the…

概率论 · 数学 2015-10-15 M. C. Mackey , M. Tyran-Kamińska , R. Yvinec

Numerical studies of the May-Leonard model for cyclically competing species exhibit spontaneous spatial structures in the form of spirals. It is desirable to obtain a simple coarse-grained evolution equation describing spatio-temporal…

统计力学 · 物理学 2017-09-08 Shannon R. Serrao , Uwe C. Täuber

Inspired by recent studies on deterministic oscillator models, we introduce a stochastic one-dimensional model for a chain of interacting particles. The model consists of $N$ oscillators performing continuous-time random walks on the…

统计力学 · 物理学 2026-02-04 Emilio N. M. Cirillo , Matteo Colangeli , Claudio Giberti , Lamberto Rondoni

Stochastic reaction-diffusion equations are a popular modelling approach for studying interacting populations in a heterogeneous environment under the influence of environmental fluctuations. Although the theoretical basis of alternative…

种群与进化 · 定量生物学 2017-02-16 Ivo Siekmann , Michael Bengfort , Horst Malchow

Under normal operations, memristive devices undergo variability in time and space and have internal dynamics. Interplay of memory and stochastic signal processing in memristive devices makes them candidates for performing bio-inspired tasks…

新兴技术 · 计算机科学 2024-08-01 P. F. Gora , Ewa Gudowska-Nowak

Unlike macroscopic multistable mechanical systems such as snap bracelets or elastic shells that must be physically manipulated into various conformations, microscopic systems can undergo spontaneous conformation switching between…

统计力学 · 物理学 2013-08-29 Ee Hou Yong , L. Mahadevan