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Uncertainty quantification is essential when dealing with ill-conditioned inverse problems due to the inherent nonuniqueness of the solution. Bayesian approaches allow us to determine how likely an estimation of the unknown parameters is…

机器学习 · 统计学 2020-01-16 Ali Siahkoohi , Gabrio Rizzuti , Felix J. Herrmann

Meta-analysis is a powerful tool to synthesize findings from multiple studies. The normal-normal random-effects model is widely used to account for between-study heterogeneity. However, meta-analysis of sparse data, which may arise when the…

统计方法学 · 统计学 2024-06-10 Taojun Hu , Yi Zhou , Satoshi Hattori

Matching is one of the most widely used study designs for adjusting for measured confounders in observational studies. However, unmeasured confounding may exist and cannot be removed by matching. Therefore, a sensitivity analysis is…

统计方法学 · 统计学 2024-01-17 Jeffrey Zhang , Dylan Small , Siyu Heng

When developing Bayesian hierarchical models, selecting the most appropriate hierarchical structure can be a challenging task, and visualisation remains an underutilised tool in this context. In this paper, we consider visualisations for…

统计方法学 · 统计学 2024-12-05 Oluwayomi Akinfenwa , Niamh Cahill , Catherine Hurley

Sensitivity analysis is an important tool used in many domains of computational science to either gain insight into the mathematical model and interaction of its parameters or study the uncertainty propagation through the input-output…

统计方法学 · 统计学 2023-06-02 Juraj Kardos , Wouter Edeling , Diana Suleimenova , Derek Groen , Olaf Schenk

The normal-normal hierarchical model (NNHM) constitutes a simple and widely used framework for meta-analysis. In the common case of only few studies contributing to the meta-analysis, standard approaches to inference tend to perform poorly,…

Causal inference relies on the untestable assumption of no unmeasured confounding. Sensitivity analysis can be used to quantify the impact of unmeasured confounding on causal estimates. Among sensitivity analysis methods proposed in the…

统计方法学 · 统计学 2026-03-12 Yushu Zou , Liangyuan Hu , Amanda Ricciuto , Mark Deneau , Kuan Liu

Inverse problems constrained by partial differential equations (PDEs) play a critical role in model development and calibration. In many applications, there are multiple uncertain parameters in a model which must be estimated. Although the…

Differential analysis is a routine procedure in the statistical analysis toolbox across many applied fields, including quantitative proteomics, the main illustration of the present paper. The state-of-the-art limma approach uses a…

统计方法学 · 统计学 2025-12-12 Marie Chion , Arthur Leroy

Many modern experiments, such as microarray gene expression and genome-wide association studies, present the problem of estimating a large number of parallel effects. Bayesian inference is a popular approach for analyzing such data by…

统计方法学 · 统计学 2018-10-26 J G Liao , Arthur Berg , Timothy L McMurry

To account for measurement error (ME) in explanatory variables, Bayesian approaches provide a flexible framework, as expert knowledge about unobserved covariates can be incorporated in the prior distributions. However, given the analytic…

统计方法学 · 统计学 2013-08-19 Stefanie Muff , Andrea Riebler , Havard Rue , Philippe Saner , Leonhard Held

We discuss Bayesian inference for parameters selected using the data. First, we provide a critical analysis of the existing positions in the literature regarding the correct Bayesian approach under selection. Second, we propose two types of…

统计理论 · 数学 2021-05-12 Daniel G. Rasines , G. Alastair Young

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

统计方法学 · 统计学 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

Bayesian synthetic likelihood (BSL) is a popular method for estimating the parameter posterior distribution for complex statistical models and stochastic processes that possess a computationally intractable likelihood function. Instead of…

统计计算 · 统计学 2019-07-26 Ziwen An , Leah F South , Christopher Drovandi

Bayesian statistics is an integral part of contemporary applied science. bayesics provides a single framework, unified in syntax and output, for performing the most commonly used statistical procedures, ranging from one- and two-sample…

统计方法学 · 统计学 2026-02-18 Daniel K. Sewell , Alan T. Arakkal

We revisit the problem of simultaneously testing the means of $n$ independent normal observations under sparsity. We take a Bayesian approach to this problem by introducing a scale-mixture prior known as the normal-beta prime (NBP) prior.…

统计方法学 · 统计学 2020-07-29 Ray Bai , Malay Ghosh

A central characteristic of Bayesian statistics is the ability to consistently incorporate prior knowledge into various modeling processes. In this paper, we focus on translating domain expert knowledge into corresponding prior…

统计方法学 · 统计学 2024-04-16 Florence Bockting , Stefan T. Radev , Paul-Christian Bürkner

Observational studies are often conducted to estimate causal effects of treatments or exposures on event-time outcomes. Since treatments are not randomized in observational studies, techniques from causal inference are required to adjust…

统计方法学 · 统计学 2023-10-23 Han Ji , Arman Oganisian

The accuracy of probability distributions inferred using machine-learning algorithms heavily depends on data availability and quality. In practical applications it is therefore fundamental to investigate the robustness of a statistical…

机器学习 · 统计学 2018-10-01 Christiane Goergen , Manuele Leonelli

Bayesian statistics has gained popularity in psychological research due to its intuitive uncertainty quantification and convenient information-updating rules. In many applications, however, prior distributions are introduced merely as…

统计方法学 · 统计学 2026-03-10 Yang Liu , Jonathan P. Williams , Jan Hannig