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A central problem of neuroscience involves uncovering the principles governing the organization of nervous systems which ensure robustness in brain development. The nematode Caenorhabditis elegans provides us with a model organism for…

神经元与认知 · 定量生物学 2020-07-01 Anand Pathak , Nivedita Chatterjee , Sitabhra Sinha

The dynamics of complex-valued fractional-order neuronal networks are investigated, focusing on stability, instability and Hopf bifurcations. Sufficient conditions for the asymptotic stability and instability of a steady state of the…

动力系统 · 数学 2017-03-21 Eva Kaslik , Ileana Rodica Radulescu

Probing the developing neural circuitry in Caenorhabditis elegans has enhanced our understanding of nervous systems. The C. elegans connectome, like those of other species, is characterized by a rich club of densely connected neurons…

神经元与认知 · 定量生物学 2021-08-26 Alec Helm , Ann S. Blevins , Danielle S. Bassett

We propose a dynamical neural network model with a hierarchical and modular structure. The network architecture can be derived by minimizing an energy function that is originally designed based on two kinds of neurons with quite different…

神经元与认知 · 定量生物学 2026-04-14 Kazuyoshi Tsutsumi , Ernst Niebur

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

适应与自组织系统 · 物理学 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

Recent efforts in neuroscience research seek to obtain detailed anatomical neuronal wiring maps as well as information on how neurons in these networks engage in dynamic activities. Although the entire connectivity map of the nervous system…

神经元与认知 · 定量生物学 2014-06-09 Tina Schrödel , Robert Prevedel , Karin Aumayr , Manuel Zimmer , Alipasha Vaziri

In the wake of recent advances in experimental methods in neuroscience, the ability to record in-vivo neuronal activity from awake animals has become feasible. The availability of such rich and detailed physiological measurements calls for…

定量方法 · 定量生物学 2016-11-03 Gal Mishne , Ronen Talmon , Ron Meir , Jackie Schiller , Uri Dubin , Ronald R. Coifman

This research report introduces ElegansNet, a neural network that mimics real-world neuronal network circuitry, with the goal of better understanding the interplay between connectome topology and deep learning systems. The proposed approach…

神经与进化计算 · 计算机科学 2024-04-01 Francesco Bardozzo , Andrea Terlizzi , Pietro Liò , Roberto Tagliaferri

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

神经元与认知 · 定量生物学 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

Advanced volumetric imaging methods and genetically encoded activity indicators have permitted a comprehensive characterization of whole brain activity at single neuron resolution in \textit{Caenorhabditis elegans}. The constant motion and…

定量方法 · 定量生物学 2022-10-12 Yuxiang Wu , Shang Wu , Xin Wang , Chengtian Lang , Quanshi Zhang , Quan Wen , Tianqi Xu

The objective of this paper is to study the dynamical behaviour systematically of an ecological system with Beddington-DeAngelis functional response which avoids the criticism occurred in the case of ratio-dependent functional response at…

动力系统 · 数学 2015-01-21 Sahabuddin Sarwardi , Md. Reduanur Mandal , Nurul Huda Gazi

The nervous system of the nematode soil worm Caenorhabditis elegans exhibits remarkable complexity despite the worm's small size. A general challenge is to better understand the relationship between neural organization and neural activity…

神经元与认知 · 定量生物学 2020-10-30 Alejandro Morales , Tom Froese

The small (1 mm) nematode $\textit{Caenorhabditis elegans}$ (Corsi [1], wormbook.org) has become widely used as a model organism; in particular, the $\textit{C. elegans}$ connectome has been completely mapped, and $\textit{C. elegans}$…

生物物理 · 物理学 2021-10-22 Anshul Singhvi , Harold M. Hastings , Jenny Magnes , Susannah G. Zhang

The dynamical responses of complex neuronal networks to external stimulus injected on a \emph{single} neuron are investigated. Stimulating the largest-degree neuron in the network, it is found that as the intensity of the stimulus…

混沌动力学 · 物理学 2016-04-13 Mengjiao Chen , Weijie Lin , Hengtong Wang , Wei Ren , Xingang Wang

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

神经元与认知 · 定量生物学 2016-11-28 Rahul Badhwar , Ganesh Bagler

Neural networks show a progressive increase in complexity during the time course of evolution. From diffuse nerve nets in Cnidaria to modular, hierarchical systems in macaque and humans, there is a gradual shift from simple processes…

神经元与认知 · 定量生物学 2011-12-23 Marcus Kaiser , Sreedevi Varier

One important question in neuroscience is how global behavior in a brain network emerges from the interplay between network connectivity and the neural dynamics of individual nodes. To better understand this theoretical relationship, we…

神经元与认知 · 定量生物学 2022-09-13 Anca Radulescu , Johan Nakuci , Simone Evans , Sarah Muldoon

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

神经元与认知 · 定量生物学 2021-04-08 R. Janaki , A. S. Vytheeswaran

In this paper, dynamical systems theory and bifurcation theory are applied to investi- gate the rich dynamical behaviours observed in three simple disease models. The 2- and 3-dimensional models we investigate have arisen in previous…

动力系统 · 数学 2015-04-22 Wenjing Zhang , Pei Yu , Lindi M. Wahl

We study the dynamics of a low-dimensional system of coupled model neurons as a step towards understanding the vastly complex network of neurons in the brain. We analyze the bifurcation structure of a system of two model neurons with…

动力系统 · 数学 2019-03-27 Elizabeth N. Davison , Zahra Aminzare , Biswadip Dey , Naomi Ehrich Leonard