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Using a sample from a population to estimate the proportion of the population with a certain category label is a broadly important problem. In the context of microbiome studies, this problem arises when researchers wish to use a sample from…

统计方法学 · 统计学 2019-02-08 Bryan D. Martin , Daniela Witten , Amy D. Willis

We study the problem of efficient exploration in order to learn an accurate model of an environment, modeled as a Markov decision process (MDP). Efficient exploration in this problem requires the agent to identify the regions in which…

Microbial biomass carbon (MBC), a crucial soil labile carbon fraction, is the most active component of the soil organic carbon (SOC) that regulates bio-geochemical processes in terrestrial ecosystems. Some studies in the literature ignore…

In Part I of this article we have developed a novel mechanobiological model of a Tissue Engineering process that accounts for the mechanisms through which an isotropic or anisotropic adherence condition regulates the active functions of the…

数值分析 · 数学 2015-12-14 Chiara Lelli , Riccardo Sacco , Paola Causin , Manuela T. Raimondi

Ecosystems dynamics is often considered as driven by a coupling of species' resource consumption and its population size dynamics. Such resource-population dynamics is captured by MacArthur-type models. One biologically relevant feature…

种群与进化 · 定量生物学 2023-07-10 Elena Bellavere , Christian H. S. Hamster , Joshua A. Dijksman

Biofilm infections on medical implants are difficult to eradicate because insufficient nutrient availability promotes antibiotic-tolerant persister cells that survive treatment and reseed growth. Existing mathematical models usually omit…

种群与进化 · 定量生物学 2025-09-23 Parna Mandal , Nigel J. Mottram , Sean McGinty

Gut microbial composition has been linked to multiple health outcomes. Yet, temporal analysis of this composition had been limited to deterministic models. In this paper, we introduce a probabilistic model for the dynamics of intestinal…

定量方法 · 定量生物学 2018-09-03 Ruiqi Zhong , Tyler Joseph , Joao B Xavier , Itsik Pe'er

Neural mass models are used to simulate cortical dynamics and to explain the electrical and magnetic fields measured using electro- and magnetoencephalography. Simulations evince a complex phase-space structure for these kinds of models;…

神经元与认知 · 定量生物学 2022-08-25 Gerald Cooray , Richard Rosch , Karl Friston

Monod's model describes the growth of microorganisms using a hyperbolic function of extracellular resource concentration. Under fluctuating or limited resource concentrations this model performs poorly against experimental data, motivating…

种群与进化 · 定量生物学 2022-12-29 Mohammad M. Amirian , Andrew J. Irwin , Zoe V. Finkel

To model the morphogenesis of rod-shaped bacterial micro-colony, several individual-based models have been proposed in the biophysical literature. When studying the shape of micro-colonies, most models present interaction forces such as…

细胞行为 · 定量生物学 2020-08-12 Marie Doumic , Sophie Hecht , Diane Peurichard

This paper aims to introduce a concept of an equilibrium point of a dynamical system which will call it almost global asymptotically stable. A biological prey-predator model is also analyzed with a modification function growth in prey…

最优化与控制 · 数学 2020-05-27 Sadiq Al-Nassir

While noise is generally associated with uncertainties and often has a negative connotation in engineering, living organisms have evolved to adapt to (and even exploit) such uncertainty to ensure the survival of a species or implement…

分子网络 · 定量生物学 2022-09-29 Corentin Briat , Mustafa Khammash

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian

Understanding how species persist under interacting stressors is a central challenge in ecology. We develop a spatially explicit reaction-diffusion framework to investigate competing species in landscapes shaped by climate variability,…

种群与进化 · 定量生物学 2026-02-02 Ton Viet Ta

Host-microbe interactions play crucial roles in marine ecosystems, but we still have very little understanding of the mechanisms that govern these relationships, the evolutionary processes that shape them, and their ecological consequences.…

We introduce and study a stochastic model for the dynamics of colonial species, which reproduce through fission or fragmentation. The fission rate depends on the relative sizes of colonies in the population, and the growth rate of colonies…

概率论 · 数学 2025-01-30 Sylvain Billiard , Charles Medous , Charline Smadi

A canonical foraging task is the patch-leaving problem, in which a forager must decide to leave a current resource in search for another. Theoretical work has derived optimal strategies for when to leave a patch, and experiments have tested…

神经元与认知 · 定量生物学 2019-12-03 Jacob D. Davidson , Ahmed El Hady

From a purely operational standpoint, the existence of microbes that can grow under extreme conditions, or "extremophiles", leads to the question of how the molecules making up these microbes can maintain both their structure and function.…

软凝聚态物质 · 物理学 2016-03-23 Q. Huang , K. N. Tran , J. M. Rodgers , D. H. Bartlett , R. J. Hemley , T. Ichiye

We study analytically and numerically a model metabolic cycle composed of an arbitrary number of species of catalytically active particles. Each species converts a substrate into a product, the latter being used as the substrate by the next…

软凝聚态物质 · 物理学 2023-09-29 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

Understanding functional diversity, the range and variability of species' roles and actions within their communities, is key to predicting and preserving the functions that sustain both nature and human well-being. In this paper, we provide…

种群与进化 · 定量生物学 2025-07-16 Ines Meraoumia , Adji Bousso Dieng