相关论文: Piggy-backing protein domains with Formal Concept …

Computational protein-protein interaction (PPI) prediction techniques can contribute greatly in reducing time, cost and false-positive interactions compared to experimental approaches. Sequence is one of the key and primary information of…

Formal Concept Analysis (FCA) is extensively used in knowledge extraction, cognitive concept learning, and data mining. However, its computational demands on large-scale datasets often require outsourcing to external computing services,…

Protein-Protein Interactions (PPIs) are fundamental in various biological processes and play a key role in life activities. The growing demand and cost of experimental PPI assays require computational methods for efficient PPI prediction.…

In this paper, a new method for PPI (proteinprotein interaction) prediction is proposed. In PPI prediction, a reliable and sufficient number of training samples is not available, but a large number of unlabeled samples is in hand. In the…

Federated domain adaptation (FDA) aims to collaboratively transfer knowledge from source clients (domains) to the related but different target client, without communicating the local data of any client. Moreover, the source clients have…

Disordered proteins play essential roles in myriad cellular processes, yet their structural characterization remains a major challenge due to their dynamic and heterogeneous nature. We here present a community-driven initiative to address…

Multiscale problems are challenging for neural network-based discretizations of differential equations, such as physics-informed neural networks (PINNs). This can be (partly) attributed to the so-called spectral bias of neural networks. To…

Domain adaptation (DA) enables knowledge transfer from a labeled source domain to an unlabeled target domain by reducing the cross-domain distribution discrepancy. Most prior DA approaches leverage complicated and powerful deep neural…

We relate two formerly independent areas: Formal concept analysis and logic of domains. We will establish a correspondene between contextual attribute logic on formal contexts resp. concept lattices and a clausal logic on coherent algebraic…

We present a simple, modular graph-based convolutional neural network that takes structural information from protein-ligand complexes as input to generate models for activity and binding mode prediction. Complex structures are generated by…

Domain generalization (DG) aims to learn a generalizable model from multiple training domains such that it can perform well on unseen target domains. A popular strategy is to augment training data to benefit generalization through methods…

Protein-protein interactions (PPIs) are fundamental to cellular function and disease mechanisms. Current learning-based PPI predictors focus on learning powerful protein representations but neglect designing specialized classification…

The strength or weakness of an algorithm is ultimately governed by the confidence of its result. When the domain of the problem is large (e.g. traversal of a high-dimensional space), a perfect solution cannot be obtained, so approximations…

In this paper we introduce domain detection as a new natural language processing task. We argue that the ability to detect textual segments which are domain-heavy, i.e., sentences or phrases which are representative of and provide evidence…

Protein domains are found on genomes with notable statistical distributions, which bear a high degree of similarity. Previous work has shown how these distributions can be accounted for by simple models, where the main ingredients are…

Computational prediction of enzymatic reactions represents a crucial challenge in sustainable chemical synthesis across various scientific domains, ranging from drug discovery to materials science and green chemistry. These syntheses rely…

Specific binding of proteins to DNA is one of the most common ways in which gene expression is controlled. Although general rules for the DNA-protein recognition can be derived, the ambiguous and complex nature of this mechanism precludes a…

The growing popularity of data mining catalyses the researchers to explore various exciting aspects of education. Early prediction of student performance is an emerging area among them. The researchers have used various predictors in…

Protein-protein interaction (PPI) extraction from published scientific literature provides additional support for precision medicine efforts. However, many of the current PPI extraction methods need extensive feature engineering and cannot…

Domain classification is the task of mapping spoken language utterances to one of the natural language understanding domains in intelligent personal digital assistants (IPDAs). This is a major component in mainstream IPDAs in industry.…