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We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

概率论 · 数学 2011-01-21 Sylvie Méléard , Sylvie Roelly

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

组织与器官 · 定量生物学 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

An individual-based model of the infectious disease spread among the urban population is considered. A system of stochastic equations, which describes changes in quantities of four population groups, susceptible, exposed, infected…

种群与进化 · 定量生物学 2011-11-11 Vasiliy Leonenko

The Crump-Young model consists of two fully coupled stochastic processes modeling the substrate and microorganisms dynamics in a chemostat. Substrate evolves following an ordinary differential equation whose coefficients depend of…

概率论 · 数学 2022-05-12 Bertrand Cloez , Coralie Fritsch

Mathematical models have been widely used to describe the collective movement of bacteria by chemotaxis. In particular, bacterial concentration waves traveling in a narrow channel have been experimentally observed and can be precisely…

偏微分方程分析 · 数学 2016-04-15 Casimir Emako , Charlène Gayrard , Axel Buguin , Luís Neves de Almeida , Nicolas Vauchelet

We model the growth of a cell population using a piecewise deterministic Markov branching tree. In this model, each cell splits into two offspring at a division rate $B(x)$, which depends on its size $x$. The size of each cell increases…

概率论 · 数学 2024-09-06 Nathalie Krell

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

生物物理 · 物理学 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

We investigate some chemostat models incorporating wall growth, competition, random fluctuations on the dilution rate, and different consumption functions (Monod and Haldane). We analyze the asymptotic behavior of the solutions of the…

动力系统 · 数学 2026-03-23 Javier López-de-la-Cruz , Felipe Rivero , Carlos R. Takaessu

We consider the chemostat model with the substrate concentration as the single measurement. We propose a control strategy that drives the system at a steady state maximizing the gas production without the knowledge of the specific growth…

最优化与控制 · 数学 2013-05-14 Alain Rapaport , Jan Sieber , Serafim Rodrigues , Mathieu Desroches

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

种群与进化 · 定量生物学 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

Lately, experimental research on microbial symbioses based on nutrient exchange and interdependence has yielded a number of interesting findings, however an in-depth mathematical description of the exact underlying dynamics of such…

种群与进化 · 定量生物学 2019-08-08 Matthias M. Fischer

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian

This paper theoretically analyzes a phenomenological stochastic model for bacterial growth. This model comprises cell division and the linear growth of cells, where growth rates and cell cycles are drawn from lognormal distributions. We…

生物物理 · 物理学 2016-06-28 Ken Yamamoto , Jun-ichi Wakita

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

细胞行为 · 定量生物学 2015-12-09 Gabriele Micali , Robert G. Endres

We present a model for a biological reactor in which bacteria tend to aggregate in flocs, as encountered in wastewater treatment plants. The influence of this flocculation on the growth dynamics of the bacteria is studied. We argue that a…

种群与进化 · 定量生物学 2007-05-23 Bart Haegeman , Claude Lobry , Jerome Harmand

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

生物物理 · 物理学 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

Experiments have recently shown the feasibility of utilising bacteria as micro-scale robotic devices, with special attention paid to the development of bacteria-driven micro-swimmers taking advantage of built-in actuation and sensing…

软凝聚态物质 · 物理学 2019-02-14 Christian Esparza Lopez , Albane Thery , Eric Lauga

The rate at which individual bacterial cells grow depends on the concentrations of cellular components such as ribosomes and proteins. These concentrations continuously fluctuate over time and are inherited from mother to daughter cells,…

种群与进化 · 定量生物学 2024-08-21 Yaïr Hein , Farshid Jafarpour

Protein distributions measured under a broad set of conditions in bacteria and yeast were shown to exhibit a common skewed shape, with variances depending quadratically on means. For bacteria these properties were reproduced by temporal…

生物物理 · 物理学 2015-10-28 Naama Brenner , C. M. Newman , Dino Osmanovic , Yitzhak Rabin , Hanna Salman , D. L. Stein

Various bacterial strains exhibit colonial branching patterns during growth on poor substrates. These patterns reflect bacterial cooperative self-organization and cybernetic processes of communication, regulation and control employed during…

凝聚态物理 · 物理学 2015-06-25 Ido Golding , Yonathan Kozlovsky , Inon Cohen , Eshel Ben-Jacob