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Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

计算机视觉与模式识别 · 计算机科学 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

Parkinson's disease (PD) is debilitating, progressive, and clinically marked by motor symptoms. As the second most common neurodegenerative disease in the world, it affects over 10 million lives globally. Existing diagnoses methods have…

机器学习 · 计算机科学 2021-11-30 Riya Tyagi , Tanish Tyagi , Ming Wang , Lujin Zhang

Parkinson disease is a very common neurodegenerative disorder. Patients usually undergo destruction of substantia nigra to develop typical symptoms such as resting tremor, hypokinesia, and rigidity. However, the exact mechanism of Parkinson…

其他定量生物学 · 定量生物学 2014-03-14 Wan-Chung Hu

Parkinson's Disease (PD) is associated with gait movement disorders, such as bradykinesia, stiffness, tremors and postural instability, caused by progressive dopamine deficiency. Today, some approaches have implemented learning…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Edgar Rangel , Fabio Martinez

The assessment of Parkinson's disease (PD) poses a significant challenge as it is influenced by various factors which lead to a complex and fluctuating symptom manifestation. Thus, a frequent and objective PD assessment is highly valuable…

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction and abnormal neural oscillations. These symptoms can be modulated through electrical stimulation. Traditional neural activity analysis in PD has…

神经元与认知 · 定量生物学 2025-02-19 Jibum Kim , Hanseul Choi , Gaeun Kim , Sunggu Yang , Eunha Baeg , Donggue Kim , Seongwon Jin , Sangwon Byun

Parkinson's disease (PD) is a neurodegenerative disease affecting about 1% of people over the age of 60, causing motor impairments that impede hand coordination activities such as writing and drawing. Many approaches have tried to support…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Mhd Adnan Albani , Riad Sonbol

Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide, yet there is no disease-modifying therapy up to this date. The biological complexity underlying PD hampers the investigation of the principal…

动力系统 · 数学 2022-12-22 Elena Righetti , Alice Antonello , Luca Marchetti , Enrico Domenici , Federico Reali

Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early…

人工智能 · 计算机科学 2022-11-29 Jingwei Li , Ruitian Wu , Tzu-liang Huang , Zian Pan , Ming-chun Huang

The temporal and spatial development of Parkinson's disease has been characterised as the progressive formation of {\alpha}-synuclein aggregations through susceptible neuronal pathways. This article describes a new model for this…

神经元与认知 · 定量生物学 2017-02-20 Míriam R. García , Mathieu Cloutier , Peter Wellstead

Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

信号处理 · 电气工程与系统科学 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

Suppression of excessively synchronous beta-band oscillatory activity in the brain is believed to suppress hypokinetic motor symptoms of Parkinson's disease. Recently, a lot of interest has been devoted to desynchronizing delayed feedback…

神经元与认知 · 定量生物学 2013-03-05 Andrey Dovzhenok , Choongseok Park , Robert M. Worth , Leonid L. Rubchinsky

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder where motor dysfunction gradually increases as the disease progress. In addition to administering dopaminergic PD-specific drugs, attending neurologists strongly…

计算机与社会 · 计算机科学 2015-11-10 Ioannis Pachoulakis , Nikolaos Papadopoulos , Cleanthe Spanaki

Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such as changes in structural disorders like DNA and chromatin,…

Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…

医学物理 · 物理学 2021-11-25 Simoni Mishra

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

音频与语音处理 · 电气工程与系统科学 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani

Parkinsons disease, PD, is a chronic condition that affects motor skills and includes symptoms like tremors and rigidity. The current diagnostic procedure uses patient assessments to evaluate symptoms and sometimes a magnetic resonance…

图像与视频处理 · 电气工程与系统科学 2022-01-14 Sabrina Zhu

As one of the most prevalent neurodegenerative disorders, Parkinson's disease (PD) has a significant impact on the fine motor skills of patients. The complex interplay of different articulators during speech production and realization of…

Parkinson's disease is a neuro-degenerative disorder affecting tens of millions of people worldwide. Lately, there has been considerable interest in systems for at-home monitoring of patients, using wearable devices which contain inertial…

应用统计 · 统计学 2017-02-08 Avishai Wagner , Naama Fixler , Yehezkel S. Resheff

A particular challenge for disease progression modeling is the heterogeneity of a disease and its manifestations in the patients. Existing approaches often assume the presence of a single disease progression characteristics which is…

机器学习 · 计算机科学 2022-07-26 Taha Ceritli , Andrew P. Creagh , David A. Clifton