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The exponential growth of neuroscientific data necessitates platforms that facilitate data management and multidisciplinary collaboration. In this paper, we introduce Pennsieve - an open-source, cloud-based scientific data management…

Accurately estimating the wiring diagram of a brain, known as a connectome, at an ultrastructure level is an open research problem. Specifically, precisely tracking neural processes is difficult, especially across many image slices. Here,…

计算机视觉与模式识别 · 计算机科学 2014-05-09 Ayushi Sinha , William Gray Roncal , Narayanan Kasthuri , Jeff W. Lichtman , Randal Burns , Michael Kazhdan

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

定量方法 · 定量生物学 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

The rapid growth of data-intensive applications such as generative AI, scientific simulations, and large-scale analytics is driving modern supercomputers and data centers toward increasingly heterogeneous and tightly integrated…

A prominent goal of neuroimaging studies is mapping the human brain, in order to identify and delineate functionally-meaningful regions and elucidate their roles in cognitive behaviors. These brain regions are typically represented by…

人机交互 · 计算机科学 2020-09-04 Roza G. Bayrak , Nhung Hoang , Colin B. Hansen , Catie Chang , Matthew Berger

Clustering is a fundamental learning task widely used as a first step in data analysis. For example, biologists use cluster assignments to analyze genome sequences, medical records, or images. Since downstream analysis is typically…

机器学习 · 计算机科学 2024-06-11 Jonathan Svirsky , Ofir Lindenbaum

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

机器学习 · 统计学 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

统计方法学 · 统计学 2022-12-06 Arkaprava Roy

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Recently, a number of cloud platforms and services have been developed for data intensive computing, including Hadoop, Sector, CloudStore (formerly KFS), HBase, and Thrift. In order to benchmark the performance of these systems, to…

分布式、并行与集群计算 · 计算机科学 2009-07-29 Robert Grossman , Yunhong Gu , Michal Sabala , Collin Bennet , Jonathan Seidman , Joe Mambratti

Distributed dataflow systems enable data-parallel processing of large datasets on clusters. Public cloud providers offer a large variety and quantity of resources that can be used for such clusters. Yet, selecting appropriate cloud…

分布式、并行与集群计算 · 计算机科学 2021-12-03 Jonathan Will , Lauritz Thamsen , Dominik Scheinert , Jonathan Bader , Odej Kao

We discuss computing issues for data analysis and image reconstruction of PET-TOF medical scanner or other medical scanning devices producing large volumes of data. Service architecture based on the grid and cloud concepts for distributed…

Multi-view clustering has become a significant area of research, with numerous methods proposed over the past decades to enhance clustering accuracy. However, in many real-world applications, it is crucial to demonstrate a clear…

机器学习 · 计算机科学 2025-02-07 Mudi Jiang , Lianyu Hu , Zengyou He , Zhikui Chen

Today, the human brain can be studied as a whole. Electroencephalography, magnetoencephalography, or functional magnetic resonance imaging techniques provide functional connectivity patterns between different brain areas, and during…

数据分析、统计与概率 · 物理学 2011-01-21 Mario Chavez , Miguel Valencia , Vito Latora , Jacques Martinerie

For the past two decades, the DB community has devoted substantial research to take advantage of cheap clusters of machines for distributed data analytics -- we believe that we are at the beginning of a paradigm shift. The scaling laws and…

数据库 · 计算机科学 2025-08-05 Bowen Wu , Wei Cui , Carlo Curino , Matteo Interlandi , Rathijit Sen

Functional connectivity is a key approach to investigate oscillatory activities of the brain that provides important insights on the underlying dynamic of neuronal interactions and that is mostly applied for brain activity analysis.…

神经元与认知 · 定量生物学 2022-02-17 Marie-Constance Corsi , Sylvain Chevallier , Fabrizio De Vico Fallani , Florian Yger

Analyzing high-dimensional data and finding hidden patterns is a difficult problem and has attracted numerous research efforts. Automated methods can be useful to some extent but bringing the data analyst into the loop via interactive…

人机交互 · 计算机科学 2017-12-04 Bing Wang , Klaus Mueller

The connectomes of different human brains are pairwise distinct: we cannot talk about an abstract "graph of the brain". Two typical connectomes, however, have quite a few common graph edges that may describe the same connections between the…

神经元与认知 · 定量生物学 2015-01-07 Balazs Szalkai , Csaba Kerepesi , Balint Varga , Vince Grolmusz

Memory-compute disaggregation promises transparent elasticity, high utilization and balanced usage for resources in data centers by physically separating memory and compute into network-attached resource "blades". However, existing designs…

分布式、并行与集群计算 · 计算机科学 2021-10-22 Seung-seob Lee , Yanpeng Yu , Yupeng Tang , Anurag Khandelwal , Lin Zhong , Abhishek Bhattacharjee

High-performance computing (HPC) is essential for tackling complex computational problems across various domains. As the scale and complexity of HPC applications continue to grow, the need for scalable systems and software architectures…

分布式、并行与集群计算 · 计算机科学 2024-08-21 Risshab Srinivas Ramesh