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The responses of synapses in the neocortex show highly stochastic and nonlinear behavior. The microscopic dynamics underlying this behavior, and its computational consequences during natural patterns of synaptic input, are not explained by…

神经元与认知 · 定量生物学 2007-05-23 Ingo C. Kleppe , Hugh P. C. Robinson

When brain signals are recorded in an electroencephalogram or some similar large-scale record of brain activity, oscillatory patterns are typically observed that are thought to reflect the aggregate electrical activity of the underlying…

神经元与认知 · 定量生物学 2013-06-04 Andre Nathan , Valmir C. Barbosa

A rigorous understanding of brain dynamics and function requires a conceptual bridge between multiple levels of organization, including neural spiking and network-level population activity. Mounting evidence suggests that neural networks of…

神经元与认知 · 定量生物学 2016-10-11 Yahya Karimipanah , Zhengyu Ma , Ralf Wessel

The collective dynamics of neural populations are often characterized in terms of correlations in the spike activity of different neurons. Open questions surround the basic nature of these correlations. In particular, what leads to…

神经元与认知 · 定量生物学 2013-06-25 David Leen , Eric Shea-Brown

We study the characteristics of weak signal detection by a recurrent neuronal network with plastic synaptic coupling. It is shown that in the presence of an asynchronous component in synaptic transmission, the network acquires selectivity…

神经元与认知 · 定量生物学 2015-05-13 Vladislav Volman , Herbert Levine

A given neural network in the brain is involved in many different tasks. This implies that, when considering a specific task, the network's connectivity contains a component which is related to the task and another component which can be…

神经元与认知 · 定量生物学 2021-03-17 Friedrich Schuessler , Alexis Dubreuil , Francesca Mastrogiuseppe , Srdjan Ostojic , Omri Barak

Non-reciprocal interactions are a defining feature of many complex systems, biological, ecological, and technological, often pushing them far from equilibrium and enabling rich dynamical responses. These asymmetries can arise at multiple…

生物物理 · 物理学 2026-02-17 Anna Poggialini , Serena Di Santo , Pablo Villegas , Andrea Gabrielli , Miguel A. Muñoz

We use a biophysical model of a local neuronal circuit to study the implications of synaptic plasticity for the detection of weak sensory stimuli. Networks with fast plastic coupling show behavior consistent with stochastic resonance.…

神经元与认知 · 定量生物学 2009-11-13 Vladislav Volman , Herbert Levine

The population activity of random networks of excitatory and inhibitory leaky integrate-and-fire (LIF) neurons has been studied extensively. In particular, a state of asynchronous activity with low firing rates and low pairwise correlations…

神经元与认知 · 定量生物学 2015-06-03 Volker Pernice , Benjamin Staude , Stefano Cardanobile , Stefan Rotter

In this report trial-to-trial variations in the synchronized responses of neural networks are offered as evidence for excitation-inhibition ratio being a dynamic variable over time scales of minutes. Synchronized network responses to…

神经元与认知 · 定量生物学 2015-01-05 Netta Haroush , Shimon Marom

We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a generalized linear model (kinetic Ising model), study their functional…

神经元与认知 · 定量生物学 2015-06-19 Benjamin Dunn , Maria Mørreaunet , Yasser Roudi

Massively parallel recordings of spiking activity in cortical networks show that covariances vary widely across pairs of neurons. Their low average is well understood, but an explanation for the wide distribution in relation to the static…

无序系统与神经网络 · 物理学 2019-08-13 David Dahmen , Markus Diesmann , Moritz Helias

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

The dynamics of local cortical networks are irregular, but correlated. Dynamic excitatory--inhibitory balance is a plausible mechanism that generates such irregular activity, but it remains unclear how balance is achieved and maintained in…

神经元与认知 · 定量生物学 2020-04-28 Alan Eric Akil , Robert Rosenbaum , Krešimir Josić

Even when driven by the same stimulus, neuronal responses are well-known to exhibit a striking level of spiking variability. In-vivo electrophysiological recordings also reveal a surprisingly large degree of variability at the subthreshold…

神经元与认知 · 定量生物学 2025-03-19 Logan A. Becker , Francois Baccelli , Thibaud Taillefumier

A perturbative method is developed for calculating the effects of recurrent synaptic interactions between neurons embedded in a network. A series expansion is constructed that converges for networks with noisy membrane potential and weak…

无序系统与神经网络 · 物理学 2009-11-10 Patrick D. Roberts

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

神经元与认知 · 定量生物学 2014-03-05 Mathieu Galtier , Jonathan Touboul

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

神经元与认知 · 定量生物学 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

Neurons in the visual cortex are correlated in their variability. The presence of correlation impacts cortical processing because noise cannot be averaged out over many neurons. In an effort to understand the functional purpose of…

机器学习 · 计算机科学 2018-04-04 Shamak Dutta , Bryan Tripp , Graham Taylor

Our understanding of neural computation is founded on the assumption that neurons fire in response to a linear summation of inputs. Yet experiments demonstrate that some neurons are capable of complex functions that require interactions…

生物物理 · 物理学 2026-03-23 Christopher W. Lynn