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Binary coagulation is an important process in aerosol dynamics by which two particles merge to form a larger one. The distribution of particle sizes over time may be described by the so-called Smoluchowski's coagulation equation. This…

数学物理 · 物理学 2021-06-25 Marina A. Ferreira

By discretising space into compartments and letting system dynamics be governed by the reaction-diffusion master equation, it is possible to derive and simulate a stochastic model of reaction and diffusion on an arbitrary domain. However,…

计算物理 · 物理学 2019-11-27 Bartosz J. Bartmanski , Ruth E. Baker

Most biochemical reactions in living cells rely on diffusive search for target molecules or regions in a heterogeneous overcrowded cytoplasmic medium. Rapid re-arrangements of the medium constantly change the effective diffusivity felt…

统计力学 · 物理学 2019-11-13 Yann Lanoiselée , Nicolas Moutal , Denis S. Grebenkov

We study the steady state of a stochastic particle system on a two-dimensional lattice, with particle influx, diffusion and desorption, and the formation of a dimer when particles meet. Surface processes are thermally activated, with…

统计力学 · 物理学 2015-05-30 A. Wolff , I. Lohmar , J. Krug , O. Biham

Dynamical systems theory provides powerful methods to extract effective macroscopic dynamics from complex systems with slow modes and fast modes. Here we derive and theoretically support a macroscopic, spatially discrete, model for a class…

偏微分方程分析 · 数学 2010-03-12 Wei Wang , A. J. Roberts

In this paper, we investigate the effects of stochastic resetting on diffusion in $\R^d\backslash \calU$, where $\calU$ is a bounded obstacle with a partially absorbing surface $\partial \calU$. We begin by considering a Robin boundary…

统计力学 · 物理学 2022-06-29 Paul C. Bressloff

Particle-based stochastic reaction-diffusion (PBSRD) models are a popular approach for studying biological systems involving both noise in the reaction process and diffusive transport. In this work we derive coarse-grained deterministic…

概率论 · 数学 2021-09-02 Samuel A. Isaacson , Jingwei Ma , Konstantinos Spiliopoulos

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

概率论 · 数学 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston

The reaction-diffusion master equation is a stochastic model often utilized in the study of biochemical reaction networks in living cells. It is applied when the spatial distribution of molecules is important to the dynamics of the system.…

数值分析 · 数学 2017-03-08 Stefan Hellander , Linda Petzold

The stochastic reaction-diffusion model driven by a multiplicative noise is examined. We construct the gradient discretisation method (GDM), an abstract framework combining several numerical method families. The paper provides the…

数值分析 · 数学 2024-07-11 Yahya Alnashri , Hasan Alzubaidi

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

分子网络 · 定量生物学 2025-12-03 Thomas P. Steele , David J. Warne

A considerable number of systems have recently been reported in which Brownian yet non-Gaussian dynamics was observed. These are processes characterised by a linear growth in time of the mean squared displacement, yet the probability…

统计力学 · 物理学 2018-11-26 V. Sposini , A. V. Chechkin , F. Seno , G. Pagnini , R. Metzler

In this paper I show that, for a class of reaction networks, the discrete stochastic nature of the reacting species and reactions results in qualitative and quantitative differences between the mean of exact stochastic simulations and the…

其他定量生物学 · 定量生物学 2008-01-03 Chetan J Gadgil

We study the well-posedness of a nonlinear reaction diffusion partial differential equation system on the half-line coupled with a stochastic dynamical boundary condition, a random system arising from the description of the chemical…

概率论 · 数学 2025-05-12 Mario Maurelli , Daniela Morale , Stefania Ugolini

Biochemical reaction networks are widely applied across scientific disciplines to model complex dynamic systems. We investigate the diffusion approximation of reaction networks with mass-action kinetics, focusing on the identifiability of…

概率论 · 数学 2026-04-29 Louis Faul , Linard Hoessly , Panqiu Xia

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

概率论 · 数学 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

Heterogeneity in gene expression across isogenic cell populations can give rise to phenotypic diversity, even when cells are in homogenous environments. This diversity arises from the discrete, stochastic nature of biochemical reactions,…

定量方法 · 定量生物学 2017-08-31 Zachary Fox , Brian Munsky

A review of the recent applications of the dispersive optical model (DOM) is presented. Emphasis is on the nonlocal implementation of the DOM that is capable of describing ground-state properties accurately when data like the nuclear charge…

核理论 · 物理学 2016-07-20 W. H. Dickhoff

We study a diffusion approximation for a model of stochastic motion of a particle in one spatial dimension. The velocity of the particle is constant but the direction of the motion undergoes random changes with a Poisson clock. Moreover,…

泛函分析 · 数学 2022-04-21 Adam Bobrowski , Tomasz Komorowski

Stochastic reaction-diffusion models are now a popular tool for studying physical systems in which both the explicit diffusion of molecules and noise in the chemical reaction process play important roles. The Smoluchowski diffusion-limited…