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相关论文: Voltage sensing in ion channels: Mesoscale simulat…

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Electrical signaling via voltage-gated ion channels depends upon the function of the voltage sensor (VS), identified with the S1-S4 domain of voltage-gated K channels. Here we investigate some physical aspects of the sliding-helix model of…

生物大分子 · 定量生物学 2015-03-13 Alexander Peyser , Wolfgang Nonner

Voltage-gated ion channels mediate electrical excitability of cellular membranes. Reduced models of the voltage sensor (VS) of Kv channels produce insight into the electrostatic physics underlying the response of the highly positively…

生物大分子 · 定量生物学 2015-03-13 Alexander Peyser

The physiology of voltage gated ion channels is complex and insights into their gating mechanism is incomplete. Their function is best represented by Markov models with relatively large number of distinct states that are connected by…

亚细胞过程 · 定量生物学 2013-12-17 Febe Francis , Míriam R. García , Oliver Mason , Richard H. Middleton

This paper proposes a network decoupling method based on Holomorphic Embedding (HE) for voltage stability analysis. Using the proposed HE method with a physical load scaling factor s, it develops a set of decoupled two-bus circuit channels…

系统与控制 · 电气工程与系统科学 2020-03-30 Qiupin Lai , Chengxi Liu , Kai Sun

We investigate the formation of the one-dimensional channels on the topological surface under the gate electrode. The energy dispersion of these channels is almost linear in the momentum with the velocity sensitively depending on the…

介观与纳米尺度物理 · 物理学 2015-05-18 Takehito Yokoyama , Alexander V. Balatsky , Naoto Nagaosa

The activation of a $K^+$ channel sensor in two sequential stages during a voltage clamp may be described as the translocation of a Brownian particle in an energy landscape with two large barriers between states. A solution of the…

生物物理 · 物理学 2015-06-22 Samuel R. Vaccaro

Voltage-gated ion channels are key molecules for the generation and propagation of electrical signals in excitable cell membranes. The voltage-dependent switching of these channels between conducting and nonconducting states is a major…

生物物理 · 物理学 2009-09-10 Riza Erdem , Ekrem Aydiner

In this work, the threshold voltage instability of normally-off p-GaN high electron mobility transistors (HEMTs) has been investigated by monitoring the gate current density during device on-state. The origin of the gate current variations…

In molecular charge transport, transition voltage spectroscopy (TVS) holds the promise that molecular energy levels can be explored at bias voltages lower than required for resonant tunneling. We investigate the theoretical basis of this…

介观与纳米尺度物理 · 物理学 2011-09-09 Fatemeh Mirjani , Joseph M. Thijssen , Sense Jan van der Molen

Quantum calculations on the voltage sensing domain (VSD) of the Kv1.2 potassium channel (pdb: 3Lut)have been carried out on a 904 atoms subset of the VSD, plus 24 water molecules. Side chains pointing away from the center of the VSD were…

生物大分子 · 定量生物学 2018-10-10 Alisher M. Kariev , Michael E. Green

The action potential signal of nerve and muscle is produced by voltage sensitive channels that include a specialized device to sense voltage. Gating currents of the voltage sensor are now known to depend on the back-and-forth movements of…

生物物理 · 物理学 2017-07-11 Tzyy-Leng Horng , Robert S. Eisenberg , Chun Liu , Francisco Bezanilla

We present transport measurements of electrons on the surface of liquid helium in a microchannel device in which a constriction may be formed by a split-gate electrode. The surface electron current passing through the microchannel first…

介观与纳米尺度物理 · 物理学 2015-05-28 David Rees , Isao Kuroda , Claire Marrache-Kikuchi , Moritz Hofer , Paul Leiderer , Kimitoshi Kono

Voltage-dependent ion channels determine the electric properties of axonal cell membranes. They not only allow the passage of ions through the cell membrane but also contribute to an additional charging of the cell membrane resulting in the…

神经元与认知 · 定量生物学 2009-11-13 G. Schmid , I. Goychuk , P. Hanggi

The methods of Nicholson and Shain and Randles-Sevcik are the paradigms of voltammetry of redox species. However, as they were originally developed for aqueous redox couples, they cannot be directly applied to solid redox films such as…

化学物理 · 物理学 2025-03-20 Keyvan Malaie

We present a simple one-dimensional trapping model prompted by the problem of ion current across biological membranes. The trap is modeled mimicking the ionic channel membrane behaviour. Such voltage-sensitive channels are open or closed…

统计力学 · 物理学 2009-10-31 Alejandro D. Sanchez , Jorge A. Revelli , Horacio S. Wio

The non-selective voltage activated cation channel from the human red cells, which is activated at depolarizing potentials, has been shown to exhibit counter-clockwise gating hysteresis. We have analyzed the phenomenon with the simplest…

统计力学 · 物理学 2009-11-11 Ewa Gudowska-Nowak , Bartlomiej Dybiec , Henrik Flyvbjerg

We propose and study a model of hypothetical magnetosensitive ionic channels which are long thought to be a possible candidate to explain the influence of weak magnetic fields on living organisms ranging from magnetotactic bacteria to…

生物物理 · 物理学 2016-03-07 Igor Goychuk

We measure transport through a Ga[Al]As heterostructure at temperatures between 0.1 K and 30 K. Increasing the temperature enhances the electron-electron scattering rate and viscous effects in the two-dimensional electron gas arise. To…

The transient behaviour of organic electrochemical transistors (OECT) is complex due to mixed ionic-electronic properties that play a central role in bioelectronics, sensing and neuromorphic applications. We investigate the impedance…

材料科学 · 物理学 2024-08-06 Juan Bisquert , Scott T. Keene

Integration of distributed energy resources has created a need for autonomous, dynamic voltage regulation. Decentralized Volt-VAr Control (VVC) of grid-connected inverters presents a unique opportunity for voltage management but, if…

系统与控制 · 电气工程与系统科学 2025-10-17 Daniel Russell , Dakota Hamilton , Mads R. Almassalkhi , Hamid R. Ossareh
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