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Cryogenic Electron Tomography (CryoET) combined with sub-volume averaging (SVA) is the only imaging modality capable of resolving protein structures inside cells at molecular resolution. Particle picking, the task of localizing and…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Linhan Wang , Jianwen Dou , Wang Li , Shengkun Wang , Zhiwu Xie , Chang-Tien Lu , Yinlin Chen

With the increasing diversity in material systems, ever-expanding number of analysis techniques, and the large capital costs of next generation instruments the ability to quickly and efficiently collect data in the electron microscope has…

材料科学 · 物理学 2022-05-10 Matthew Olszta , Kevin Fiedler

Computed tomography (CT) can capture volumes large enough to measure a statistically meaningful number of micron-sized particles with a sufficiently good resolution to allow for the analysis of individual particles. However, the development…

Low-electron-dose observation is indispensable for observing various samples using a transmission electron microscope; consequently, image processing has been used to improve transmission electron microscopy (TEM) images. To apply such…

图像与视频处理 · 电气工程与系统科学 2022-03-02 Hiroyasu Katsuno , Yuki Kimura , Tomoya Yamazaki , Ichigaku Takigawa

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

计算机视觉与模式识别 · 计算机科学 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

Fine-grained visual categorization is a classification task for distinguishing categories with high intra-class and small inter-class variance. While global approaches aim at using the whole image for performing the classification,…

计算机视觉与模式识别 · 计算机科学 2020-07-07 Dimitri Korsch , Paul Bodesheim , Joachim Denzler

Multislice electron ptychography (MEP) is an inverse imaging technique that computationally reconstructs the highest-resolution images of atomic crystal structures from diffraction patterns. Available algorithms often solve this inverse…

图像与视频处理 · 电气工程与系统科学 2025-07-28 Christian K. Belardi , Chia-Hao Lee , Yingheng Wang , Justin Lovelace , Kilian Q. Weinberger , David A. Muller , Carla P. Gomes

Transmission electron diffraction is a powerful and versatile structural probe for the characterization of a broad range of materials, from nanocrystalline thin films to single crystals. With recent developments in fast electron detectors…

Cryo-electron tomography (cryo-ET) has emerged as a powerful technique for imaging macromolecular complexes in their near-native states. However, the localization of 3D particles in cellular environments still presents a significant…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Gokul Adethya , Bhanu Pratyush Mantha , Tianyang Wang , Xingjian Li , Min Xu

Automated recognition and classification of bacteria species from microscopic images have significant importance in clinical microbiology. Bacteria classification is usually carried out manually by biologists using different shapes and…

定量方法 · 定量生物学 2019-12-19 Muhammed Talo

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

This paper presents a systematic solution for the intelligent recognition and automatic analysis of microscopy images. We developed a data engine that generates high-quality annotated datasets through a combination of the collection of…

图像与视频处理 · 电气工程与系统科学 2025-08-27 Yanhui Hong , Nan Wang , Zhiyi Xia , Haoyi Tao , Xi Fang , Yiming Li , Jiankun Wang , Peng Jin , Xiaochen Cai , Shengyu Li , Ziqi Chen , Zezhong Zhang , Guolin Ke , Linfeng Zhang

In this paper, 3D image data of ore particle systems is investigated. By combining X-ray micro tomography (XMT) with scanning electron microscope (SEM) based image analysis additional information about the mineralogical composition from…

图像与视频处理 · 电气工程与系统科学 2018-06-11 Orkun Furat , Thomas Leißner , Ralf Ditscherlein , Ondřej Šedivý , Matthias Weber , Kai Bachmann , Jens Gutzmer , Urs Peuker , Volker Schmidt

Motivation: Cellular Electron CryoTomography (CECT) enables 3D visualization of cellular organization at near-native state and in sub-molecular resolution, making it a powerful tool for analyzing structures of macromolecular complexes and…

定量方法 · 定量生物学 2017-04-14 Min Xu , Xiaoqi Chai , Hariank Muthakana , Xiaodan Liang , Ge Yang , Tzviya Zeev-Ben-Mordehai , Eric Xing

Classification of rocks is one of the fundamental tasks in a geological study. The process requires a human expert to examine sampled thin section images under a microscope. In this study, we propose a method that uses microscope…

计算机视觉与模式识别 · 计算机科学 2021-06-24 S. Joseph , H. Ujir , I. Hipiny

Automated experiments in scanning transmission electron microscopy (STEM) require rapid image segmentation to optimize data representation for human interpretation, decision-making, site-selective spectroscopies, and atomic manipulation.…

Scanning Electron Microscopy (SEM) is pivotal in revealing intricate micro- and nanoscale features across various research fields. However, obtaining high-resolution SEM images presents challenges, including prolonged scanning durations and…

图像与视频处理 · 电气工程与系统科学 2024-10-08 Tom Reclik , Setareh Medghalchi , Philipp Schumacher , Maximilian Wollenweber , Talal Al-Samman , Sandra Korte-Kerzel , Ulrich Kerzel

The most established method of reconstructing neural circuits from animals involves slicing tissue very thin, then taking mosaics of electron microscope (EM) images. To trace neurons across different images and through different sections,…

定量方法 · 定量生物学 2013-04-23 Louis K. Scheffer , Bill Karsh , Shiv Vitaladevun

Microscopy is the workhorse of the physical and life sciences, producing crisp images of everything from atoms to cells well beyond the capabilities of the human eye. However, the analysis of these images is frequently little better than…

软凝聚态物质 · 物理学 2017-10-18 Matthew Bierbaum , Brian D. Leahy , Alexander A. Alemi , Itai Cohen , James P. Sethna

Cryo-electron microscopy (cryo-EM) enables the atomic-resolution visualization of biomolecules; however, modern direct detectors generate data volumes that far exceed the available storage and transfer bandwidth, thereby constraining…

图像与视频处理 · 电气工程与系统科学 2026-03-31 Zain Shabeeb , Daniel Saeedi , Darin Tsui , Vida Jamali , Amirali Aghazadeh