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We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal…

细胞行为 · 定量生物学 2009-11-10 Carlos Escudero

We study colonies of non-motile, rod-shaped bacteria growing on solid substrates. In our model, bacteria interact purely mechanically, by pushing each other away as they grow, and consume a diffusing nutrient. We show that mechanical…

生物物理 · 物理学 2015-06-15 F. D. C. Farrell , O. Hallatschek , D. Marenduzzo , B. Waclaw

A discrete chemotactic predator-prey model is proposed in which the prey secrets a diffusing chemical which is sensed by the predator and vice versa. Two dynamical states corresponding to catching and escaping are identified and it is shown…

种群与进化 · 定量生物学 2015-05-20 Ankush Sengupta , Tobias Kruppa , Hartmut Löwen

Chemotaxis, the movement of an organism in response to chemical stimuli, is a typical feature of many microbiological systems. In particular, the social amoeba \textit{Disctyostelium discoideum} is widely used as a model organism, but it is…

细胞行为 · 定量生物学 2025-08-04 Daniele Proverbio , Marco Maggiora

In modeling the inflammatory response to a lesion in an artery wall, there are a number of chemotactic mechanisms going on within the wall layer that lead to an arterial plaque. We introduce a rather reduced model of these dynamic…

偏微分方程分析 · 数学 2015-11-10 Jonathan Bell , Animikh Biswas

A large variety of microorganisms produce molecules to communicate via complex signaling mechanisms such as quorum sensing and chemotaxis. The biological diversity is enormous, but synthetic inanimate colloidal microswimmers mimic…

软凝聚态物质 · 物理学 2019-10-01 Jens Grauer , Hartmut Löwen , Avraham Be'er , Benno Liebchen

Lately, experimental research on microbial symbioses based on nutrient exchange and interdependence has yielded a number of interesting findings, however an in-depth mathematical description of the exact underlying dynamics of such…

种群与进化 · 定量生物学 2019-08-08 Matthias M. Fischer

The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can…

定量方法 · 定量生物学 2015-06-04 Vanni Bucci , Serena Bradde , Giulio Biroli , Joao B. Xavier

The striking variety of macroscopic morphologies displayed by bacterial colonies depends on microscopic environmental and behavioural details in a manner that is currently not well understood. A surprising example is sibling inhibition,…

细胞行为 · 定量生物学 2026-05-15 Dario Buonomo , Francesco Imperi , Fabio Bruni , Marco Polin , Barbara Capone

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

生物物理 · 物理学 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

To model the morphogenesis of rod-shaped bacterial micro-colony, several individual-based models have been proposed in the biophysical literature. When studying the shape of micro-colonies, most models present interaction forces such as…

细胞行为 · 定量生物学 2020-08-12 Marie Doumic , Sophie Hecht , Diane Peurichard

The present work was inspired by the recent developments in laboratory experiments made on chip, where culturing of multiple cell species was possible. The model is based on coupled reaction-diffusion-transport equations with chemotaxis,…

数值分析 · 数学 2020-07-22 E. C. Braun , G. Bretti , R. Natalini

Chemotaxis plays a crucial role in a variety of processes in biology and ecology. Quite often it acts to improve efficiency of biological reactions; one example is the immune system signalling, where infected tissues release chemokines…

偏微分方程分析 · 数学 2025-08-20 Jing An , Alexander Kiselev , Yao Yao

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

生物物理 · 物理学 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

We present a two-species population model in a well-mixed environment where the dynamics involves, in addition to birth and death, changes due to environmental factors and inter-species interactions. The novel dynamical components are…

生物物理 · 物理学 2020-09-17 J. J. Dong , J. D. Russo , K. Sampson

The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

细胞行为 · 定量生物学 2015-01-19 Anatolij Gelimson , Ramin Golestanian

Many bacterial species produce toxins that inhibit their competitors. We model this phenomenon by extending classic two-species Lotka-Volterra competition in one spatial dimension to incorporate toxin production by one species. Considering…

种群与进化 · 定量生物学 2019-09-23 Andrew D. Dean , Malcolm J. Horsburgh , Bakhti Vasiev

This paper studies a chemotaxis system where cells move in response to a chemical signal within a confined habitat. The model includes external source terms that combine local and nonlocal growth with dampening effects. The main focus is on…

偏微分方程分析 · 数学 2025-11-11 Rafael Diaz Fuentes , Fatma Gamze Duzgun , Silvia Frassu , Giuseppe Viglialoro

Microorganisms can preferentially orient and move along gradients of a chemo-attractant (i.e., chemotax) while colonies of many microorganisms can collectively undergo complex dynamics in response to chemo-attractants that they themselves…

生物物理 · 物理学 2013-10-30 Enkeleida Lushi , Raymond E. Goldstein , Michael J. Shelley

Advances in synthetic biology allow us to engineer bacterial collectives with pre-specified characteristics. However, the behavior of these collectives is difficult to understand, as cellular growth and division as well as extra-cellular…

细胞行为 · 定量生物学 2017-09-13 James J. Winkle , Oleg Igoshin , Matthew R. Bennett , Krešimir Josić , William Ott
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