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Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation through a nanochannel embedded in two dimensions under an applied external field. We examine the translocation time for…

软凝聚态物质 · 物理学 2012-03-26 Huaisong Yong , Yilin Wang , Shichen Yuan , Bi Xu , Kaifu Luo

Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a narrow channel of width $R$ embedded in two dimensions, driven by a force proportional to the number of monomers in…

软凝聚态物质 · 物理学 2011-08-26 Kaifu Luo , Ralf Metzler

Polymer translocation through a nanopore in a membrane investigated theoretically. Recent experiments on voltage-driven DNA and RNA translocations through a nanopore indicate that the size and geometry of the pore are important factors in…

统计力学 · 物理学 2009-11-07 Elena Slonkina , Anatoly B. Kolomeisky

The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

统计力学 · 物理学 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

We show that the injection of polymer chains into nanochannels becomes easier as the channel becomes narrower. This counter intuitive result arises because of a decrease in the diffusive time scale of the chains with increasing confinement.…

软凝聚态物质 · 物理学 2012-07-16 Rodrigo Ledesma-Aguilar , Takahiro Sakaue , Julia M. Yeomans

Using two dimensional Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a fluidic channel with diameter $R$ through a nanopore under a driving force $F$. Due to the crowding effect induced by the…

软凝聚态物质 · 物理学 2010-08-30 Kaifu Luo , Ralf Metzler

The motion of polymers with inhomogeneous structure through nanopores is discussed theoretically. Specifically, we consider the translocation dynamics of polymers consisting of double-stranded and single-stranded blocks. Since only the…

统计力学 · 物理学 2009-11-11 Stanislav Kotsev , Anatoly B. Kolomeisky

The transport of biomolecules across a cell membrane is an important phenomena that plays a pivotal role in the functioning of biological cells. In this paper, we investigate such processes by modeling the translocation of polymers through…

软凝聚态物质 · 物理学 2022-11-01 Andri Sharma

We consider the dynamics of pore-driven polymer translocation through a nanopore to semi-infinite space when the chain is initially confined and equilibrated in a narrow channel. To this end, we use Langevin dynamics (LD) simulations and…

软凝聚态物质 · 物理学 2025-03-11 Soheila Emamyari , Jalal Sarabadani , Ralf Metzler , Tapio Ala-Nissila

We suggest a theoretical description of the force-induced translocation dynamics of a polymer chain through a nanopore. Our consideration is based on the tensile (Pincus) blob picture of a pulled chain and the notion of propagating front of…

软凝聚态物质 · 物理学 2012-04-17 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

Most of the theoretical models describing the translocation of a polymer chain through a nanopore use the hypothesis that the polymer is always relaxed during the complete process. In other words, models generally assume that the…

生物大分子 · 定量生物学 2009-11-13 Michel G. Gauthier , Gary W. Slater

We study the translocation of polymers across varying-section channels. Using systematic approximations, we derive a simplified model that reduces the problem of polymer translocation through varying-section channels to that of a point-like…

软凝聚态物质 · 物理学 2017-07-13 Valentino Bianco , Paolo Malgaretti

We investigate the influence of varying confinement on the dynamics of polymer translocation through a cone shaped channel. For this, a linear polymer chain is modeled by a self voiding walks (SAWs) on a square lattice. The cis-side of a…

软凝聚态物质 · 物理学 2024-01-10 Manish Dwivedi , Sumitra Rudra , Sanjay Kumar

We investigate polymer translocation through a nanopore under a pulling force using Langevin dynamics simulations. We concentrate on the influence of the chain length $N$ and the pulling force $F$ on the translocation time $\tau$. The…

软凝聚态物质 · 物理学 2007-06-27 Ilkka Huopaniemi , Kaifu luo , Tapio Ala-Nissila , See-Chen Ying

We examine pressure-driven non-equilibrium transport of linear, circular and star polymers through a nanochannel containing a rectangular pit with full hydrodynamic interactions and thermal fluctuations. We demonstrate that with…

软凝聚态物质 · 物理学 2015-06-18 Santtu T. T. Ollila , Colin Denniston , Mikko Karttunen , Tapio Ala-Nissila

The translocation time of a polymer chain through an interaction energy gradient nanopore was studied by Monte Carlo simulations and the Fokker-Planck equation with double-absorbing boundary conditions. Both the simulation and calculation…

软凝聚态物质 · 物理学 2017-01-04 Meng-Bo Luo , Shuang Zhang , Fan Wu , Li-Zhen Sun

We investigate the dynamics of polymer translocation through a nanopore using two-dimensional Langevin dynamics simulations. In the absence of external driving force, we consider a polymer which is initially placed in the middle of the pore…

软凝聚态物质 · 物理学 2007-05-23 Ilkka Huopaniemi , Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying

We investigate the translocation dynamics of heteropolymers driven through a nanopore using a constant temperature Langevin thermostat. Specifically, we consider heteropolymers consisting of two types of monomers labeled A and B, which are…

软凝聚态物质 · 物理学 2007-05-23 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Aniket Bhattacharya

We expand the blob theory for freely-jointed chains and perform molecular dynamics simulations to study the behavior of polymers confined in cylindrical channels. From weak to strong confinement, five scaling regimes, de Gennes, extended de…

软凝聚态物质 · 物理学 2018-06-18 Yu-Lin Lee , Pai-Yi Hsiao

We consider the passage of long polymers of length N through a hole in a membrane. If the process is slow, it is in principle possible to focus on the dynamics of the number of monomers s on one side of the membrane, assuming that the two…

软凝聚态物质 · 物理学 2009-11-10 Yacov Kantor , Mehran Kardar
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