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We have developed a mathematical model for in-host virus dynamics that includes spatial chemotaxis and diffusion across a two dimensional surface representing the vaginal or rectal epithelium at primary HIV infection. A linear stability…

定量方法 · 定量生物学 2016-03-07 Ognjen Stancevic , Christopher Angstmann , John M. Murray , Bruce I. Henry

Planning, implementation and evaluation of public health policies to control the human immunodeficiency virus (HIV) epidemic require regular monitoring of disease burden. This includes the proportion living with HIV, whether diagnosed or…

统计方法学 · 统计学 2014-05-20 Daniela De Angelis , Anne M. Presanis , Stefano Conti , A. E. Ades

The structure of sexual contacts, its contacts network and its temporal interactions, play an important role in the spread of sexually transmitted infections. Unfortunately, that kind of data is very hard to obtain. One of the few…

物理与社会 · 物理学 2015-06-11 Alexsandro M. Carvalho , Sebastian Goncalves

Amsterdam and other UNAIDS Fast-Track cities aim for zero new HIV infections. Utilising molecular and clinical data of the ATHENA observational HIV cohort, our primary aims are to estimate the proportion of undiagnosed HIV infections and…

Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy…

应用统计 · 统计学 2020-09-03 Zhou Lan , Le Bao

The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models, such as the Susceptible-Infected-Recovered model, Belief…

物理与社会 · 物理学 2017-07-05 Jacopo Bindi , Alfredo Braunstein , Luca Dall'Asta

We present a thorough inspection of the dynamical behavior of epidemic phenomena in populations with complex and heterogeneous connectivity patterns. We show that the growth of the epidemic prevalence is virtually instantaneous in all…

无序系统与神经网络 · 物理学 2007-05-23 Marc Barthelemy , Alain Barrat , Romualdo Pastor-Satorras , Alessandro Vespignani

Most infectious diseases spread on a dynamic network of human interactions. Recent studies of social dynamics have provided evidence that spreading patterns may depend strongly on detailed micro-dynamics of the social system. We have…

物理与社会 · 物理学 2015-09-23 Arkadiusz Stopczynski , Alex Sandy Pentland , Sune Lehmann

A central challenge in Human Immunodeficiency Virus (HIV) public health policy lies in determining whether to universally expand treatment access, despite the risk of sub-optimal adherence and consequent drug resistance, or to adopt a more…

定量方法 · 定量生物学 2025-07-16 Ashish Poonia , Siddhartha P. Chakrabarty

Dynamic models have been successfully used in producing estimates of HIV epidemics at national level, due to their epidemiological nature and their ability to simultaneously estimate prevalence, incidence, and mortality rates. Recently, HIV…

统计方法学 · 统计学 2016-02-19 Le Bao , Ben Sheng , Xiaoyue Niu , Yuan Tang , Tim Brown , Peter D. Ghys , Jeff W. Eaton

Real epidemic spreading networks often composed of several kinds of networks interconnected with each other, and the interrelated networks have the different topologies and epidemic dynamics. Moreover, most human diseases are derived from…

物理与社会 · 物理学 2017-06-21 Zhongpu Xu , Xinchu Fu

It has recently become established that the spread of infectious diseases between humans is affected not only by the pathogen itself but also by changes in behavior as the population becomes aware of the epidemic; for example, social…

物理与社会 · 物理学 2013-10-09 Yilei Bu , Steve Gregory , Harriet L. Mills

Improved mobility not only contributes to more intensive human activities but also facilitates the spread of communicable disease, thus constituting a major threat to billions of urban commuters. In this study, we present a multi-city…

物理与社会 · 物理学 2020-02-11 Xinwu Qian , Lijun Sun , Satish V. Ukkusuri

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

社会与信息网络 · 计算机科学 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

We are interested in the spread of an epidemic between two communities that have higher connectivity within than between them. We model the two communities as independent Erdos-Renyi random graphs, each with n vertices and edge probability…

概率论 · 数学 2012-10-15 David Sivakoff

Background: Men and women with a migration background comprise an increasing proportion of incident HIV cases across Western Europe. Several studies indicate a substantial proportion acquire HIV post-migration. Methods: We used partial HIV…

Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the world. Persistent oncogenic Human papillomavirus infection has been a leading threat to global health and can lead to serious complications such…

种群与进化 · 定量生物学 2024-11-13 Weiyi Wang , Shailendra Sawleshwarkar , Mahendra Piraveenan

An investigation was conducted to study the robustness of the results obtained from the cellular automata model which describes the spread of the HIV infection within lymphoid tissues [R. M. Zorzenon dos Santos and S. Coutinho, Phys. Rev.…

生物物理 · 物理学 2008-07-21 P. H. Figueirêdo , S. Coutinho , R. M. Zorzenon dos Santos

Recently, some studies have revealed that non-Poissonian statistics of human behaviors stem from the hierarchical geographical network structure. On this view, we focus on epidemic spreading in the hierarchical geographical networks, and…

物理与社会 · 物理学 2015-06-04 Zhi-Dan Zhao , Ying Liu , Ming Tang

Contact patterns in populations fundamentally influence the spread of infectious diseases. Current mathematical methods for epidemiological forecasting on networks largely assume that contacts between individuals are fixed, at least for the…

种群与进化 · 定量生物学 2007-05-23 Erik Volz , Lauren Ancel Meyers